Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital (original) (raw)
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Assessment of quality of life of cancer patients in a tertiary carehospital of South India
2012
Background: Quality of Life (QOL) measures have now become a vital part of health outcome appraisal and an effective way of capturing the personal and social context of patients. Aim: To assess the QOL of cancer patients by using a validated questionnaire. Settings and Design: A prospective study in the medical oncology clinic of a tertiary care hospital of South India. Materials and Methods: Patients receiving chemotherapy for different types of cancer were subjected to a validated questionnaire and their responses to the factors of the questionnaire were scored and analyzed. A Chi-square test was performed to assess the effect of age and type of cancer on the QOL of patients. Pearson′s correlation was done to assess the factors that had greater influence on the QOL. Results: A total of 32 (15 males; 17 females) patients were included and majority were in the age range of 61-80 years. Eleven types of cancer were identified. About 56% of the patients were assessed to have average QO...
A Review on Quality of Life in Cancer Patients: An Indian Scenario
International Journal of Current Research and Review, 2017
Cancer is a major public health concern among million of people worldwide and claims thousands of life. The main aim of this review article was to assess the Quality of life (QOL) in Indian cancer patients. QOL is a vital health outcome measure that can only be described in individual terms. It integrates several aspects of life and takes into account impact of illness and treatment. According to the available articles and literature reviews it is found that most of the patients were leading unsatisfactory QOL. Various domains such as physical, psychological, social dimensions etc are affected which in turn influenced the QOL of the patient. Factors such as pain, reduced working capability, and disturbed sleep pattern were significantly found to be affecting the QOL of cancer patients.
2016
Objective: To compare the Quality of Life (QOL) of cancer patients at different chemotherapy (CT) cycles.Study Design: Cross sectional analytical.Place and Duration of Study: Tertiary Care Hospital, Rawalpindi.Material and Methods: Study was conducted in a Tertiary Care Hospital in Rawalpindi. Non-probability purposive sampling technique was used to select a sample of 50 cancer patients undergoing chemotherapy. The patients were grouped in two on the basis of number of chemotherapy cycles, those having ≤ 2 CT cycles and those undergoing >2 CT cycles. After taking informed consent the data was collected using the European Quality of Life Questionnaire (EORTC QLQ-C30) to measure QOL in the patients. Data was entered and analyzed using SPSS version 21. Baseline distinctiveness (demographic and HRQOL) was summarized by descriptive statistics. Mean and standard deviation of individual items in the two scales was calculated in two groups and statistical inference was drawn using Indepe...
35-44 of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital
2020
This research entitled "Quality of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan" was conducted to assess the quality of life of cancer patients. It was carried out among patients attending B. P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan. Background: In patients with different type of cancers and the quality of life (QoL) improvement is the main goal, since survival can be prolonged marginally. A diagnosis is very stressful for people, affecting all aspects of their being and quality of life. Up to date, knowledge on QoL impairments throughout the entire treatment process, often including several treatment modalities is scarce. One objective of this study was to assess the quality of life of cancer patient undergoing cancer treatment. Methods: A quantitative, cross-sectional, descriptive, design was adapted. A total of 245 cancer patients above 20 years old, were enrolled in the studies during August-Se...
https://ijshr.com/IJSHR\_Vol.7\_Issue.1\_Jan2022/IJSHR-Abstract.031.html, 2022
The global cancer burden is estimated to have risen to 18.1 million new cases and 9.6 million deaths in 2018. One in 5 men and one in 6 women worldwide develop cancer during their lifetime, and one in 8 men and one in 11 women die from the disease. Worldwide, the total number of people who are alive within 5 years of a cancer diagnosis, called the 5-year prevalence, is estimated to be 43.8 million. The increasing cancer burden is due to several factors, including population growth and ageing as well as the changing prevalence of certain causes of cancer linked to social and economic development. Methods: The research approach adopted in this present study is quantitative non experimental approach and the research design Descriptive Cross sectional Explorative design. 50 samples of cancer patients who are receiving chemotherapy at selected hospitals of bagalkot, were selected by disproportionate stratified random sampling technique. A structured questionnaire was developed to collect the demographic information, a structured questionnaire was developed to assess the level of quality of life, Pain, Nausea and Vomiting, Stress and Anxiety. The level of pain will be assessed with the use of a numeric pain scale. The nausea and vomiting will be measured by Standardised MASCC Antiemesis Tool (MAT), Stress will be measured by Cohen’s perceived stress scale. The degree of anxiety will be measured by Zung self-rating anxiety scale (SAS). The data collected and analyzed using descriptive and inferential statistics. Results: The level of knowledge regarding cancer among cancer patients reveals that, Most of patients (34%) had moderate QOL knowledge, 22% of them had high QOL knowledge, 40% of them had power QOL knowledge. The level of knowledge regarding cancer among cancer patients reveals that, Most of patients (44%) had worst possible pain, 40% of them had moderate pain, 16% of them had mild pain, 0% them had no pain. The level of nausea and vomiting of cancer among cancer patients reveals that, Most of patients (64%) had high nausea and vomiting, 26% of them had moderate nausea and vomiting, 6% had low nausea and vomiting, 4% of them had minimal nausea and vomiting. The level of stress level among cancer patients reveals that, Most of patients (58%) had high stress level, 28% of them had moderate stress level, 14% of them had low stress level. The level of anxiety regarding cancer among cancer patients reveals that, Most of patients (40%) had mild to moderate anxiety level, 30% of them had moderate to severe anxiety level, 24% of them had extreme anxiety level, 6% of them had normal range level. Assessment of the level of Quality of life of the cancer patients reveals that majority The level of knowledge regarding cancer among cancer patients reveals that, Most of patients (38%) had moderate QOL knowledge, 22% of them had high QOL knowledge, 40% of them had power QOL knowledge. The level of quality of life of cancer among cancer patients reveals that, Most of patients (44%) had worst possible pain, 40% of them had moderate pain, 16% of them had mild pain, 0% them had no pain. The level of quality of life of cancer among cancer patients reveals that, Most of patients (64%) had high nausea and vomiting, 26% of them had moderate nausea and vomiting, 6% had low nausea and vomiting, 4% of them had minimal nausea and vomiting. The level of quality of life of cancer among cancer patients reveals that, Most of patients (58%) had high stress level, 28% of them had moderate stress level, 14% of them had low stress level. The level of knowledge regarding cancer among cancer patients reveals that, Most of patients (40%) had mild to moderate anxiety level, 30% of them had moderate to severe anxiety level, 24% of them had extreme anxiety level, 6% of them had normal range level. The mean, SD, and mean percentage of knowledge scores of cancer patients reveals that, The total mean percentage of Physical well being was 20.6%, mean 103.71 and SD 38.25. The total mean percentage of social well being was 21.2%, mean 106.28 and SD 33.50. The total mean percentage of emotional well being was 22%, mean 110.66 and SD 34.45. The total mean percentage of functional well being was 22.2%, mean 111.28 and SD 37.05. The mean, SD, and mean percentage of knowledge scores of cancer patients reveals that, The total mean percentage of numeric pain scale was 30.2%, mean 151 and SD 42.05. The mean, SD, and mean percentage of knowledge scores of cancer patients reveals that, The total mean percentage of MASCC antiemesis scale was 91.1%, mean 45.5 and SD 8.33. The mean, SD, and mean percentage of knowledge scores of cancer patients reveals that, The total mean percentage of Perceived stress scale was 11.2%, mean 56 and SD 14.75. The mean, SD, and mean percentage of knowledge scores of cancer patients reveals that, The total mean percentage of Zung-self rating scale was 20.4%, mean 102.78 and SD 44.12. Conclusion: Finding shows that, there is significant difference in knowledge especially cancer patient who are fighting with cancer cells in their body showing maximum symptoms related to adverse effects of treatment.
Quality of Life Assessment in Cancer Patients of Regional Centre of Hyderabad City
Journal of Applied Pharmaceutical Science, 2018
The present study was carried out to determine the quality of life in regional cancer patients of Hyderabad city with an objective to create awareness about the various health related issues and financial problems underlying the disease. So that possible measures can be taken by the society and the government in advance to improve the quality of life in cancer patients. The complete data for the present study has been collected for a period of 2 months from Mehdi Nawaz Jung Institute of Oncology and Regional Cancer Centre, Red Hills, Hyderabad, Telangana, India from 192 Females and 32 Males in the age group between 18-70 years. The quality of life of the cancer subjects was assessed using EORTC QLQ-C-30 questionnaire. The observations have shown that the cancer patients in spite of having better functioning and minimum symptoms, their perception was that they had poor quality of life. It is concluded that the therapy should be individualized for each patient not just based upon the type or stage of cancer but also based on the patient's priorities, concerns and symptoms along with treating the disease. In simple words it can be said that the therapy should be patient oriented rather than disease oriented.
Abstract This research entitled “Quality of Life of Patients Undergoing Cancer Treatment in B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan” was conducted to assess the quality of life of cancer patients. It was carried out among patients attending B. P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan. Background: In patients with different type of cancers and the quality of life (QoL) improvement is the main goal, since survival can be prolonged marginally. A diagnosis is very stressful for people, affecting all aspects of their being and quality of life. Up to date, knowledge on QoL impairments throughout the entire treatment process, often including several treatment modalities is scarce. One objective of this study was to assess the quality of life of cancer patient undergoing cancer treatment. Methods: A quantitative, cross-sectional, descriptive, design was adapted. A total of 245 cancer patients above 20 years old, were enrolled in the studies during August-September, 2013. Inclusion criteria were patients who had already received at least one type of cancer treatment and had attended the hospital for receiving the same or next type of treatment again. Exclusion criteria were any other chronic co-morbidity condition that could be influenced their QoL. The most commonly listed medical co-morbidities were: diabetes mellitus, hypertension, coronary artery disease. Cancer patients who have Eastern Co-operative Oncology Group (ECOG) performance status of 4 (i.e. fully bed-ridden) were excluded from the study. The data was collected by interview, using modified, structured scale of European Organization for Research and Treatment of Cancer Quality of life Questionnaire (EORTC QLQ- C30), prepared by the EORTC group. Information about the patient’s disease condition and treatment were obtained from the patient’s medical records. The collected data was analyzed by using SPSS version 16. Descriptive and inferential statistics were used to describe the respondent’s quality of life (QoL) scores and to identify the factors affecting it respectively. Results: The study findings revealed the quality of life of cancer patients to be influenced by many factors such as: site of cancer, stage of cancer, time elapsed since diagnosis and Eastern Co-operative Oncology Group (ECOG) performance status. The average QoL scores (out of 100) for different scales were 85.54 (global health/QoL), 77.03 (functional), and 16.14 (symptom). Loss of appetite was the most frequent complaint (mean = 20.27) and was present in almost all the patients. As the overall QoL of the patients was significantly correlated with different QoL scales as-, cognitive, emotional, physical, social, role functioning, pain, fatigue, dyspnoea, loss of appetite and nausea/vomiting and financial problem. Conclusion: Hence, in average, the quality of life of cancer patients was found to be relatively better, although there were higher ratings for some (as: cognitive, physical, role and emotional functioning) and lower for others (like social functioning). Additional research should be done in this area for improving the quality of life of specific type of cancer patients in Nepal, though the findings of this study are expected to provide the baseline knowledge regarding it. Keywords: quality of life, cancer patient, EORTC QLQ- C30
Indian Journal of Pharmaceutical Sciences , 2014
Over the last decade, quality of life investigations of cancer patients' have became a critical evaluation parameter in the clinical cancer research and treatment evaluation programs. This study was carried out in a 1200 bed tertiary care teaching hospital, MGM Hospital, located at Warangal, India. Present study assessed the overall quality of life, symptoms of patients affected by breast, head and neck, cervical and stomach cancers by using guidelines and modules of The European Organisation for Research and Treatment of Cancer. The assessment was carried out in two phases, as review I at ≤2 cycles and review II at ≥5 cycles of treatment. Data were analyzed for 104 individuals with the mean age of 46.111.2 years. The evaluation was characterised as functional scale and symptom scale. In the functional scale physical, and role functions were significant (P<0.05) in all the 4 types of cancers studied. Additional, future perspective, social and emotional functions were observed to be significant in breast cancer, head and neck cancer and cervical cancer, respectively. Where as in symptom scale pain was observed to be significant for all cancers studied. Individually, breast cancer patient also showed significant parameters like fatigue, arm symptoms, and upset by hair loss. Head and neck cancer patients had insomnia and diarrhoea as additional significant symptom scale parameters. In cervical cancer patients, fatigue, insomnia, menopausal symptoms, and in stomach cancer patients, nausea and vomiting, dysphagia, reflex symptoms and eating restrictions were significantly affected. Most of the findings are similar to past studies in the respective type of cancer patients which shows that, quality of life was mostly influenced by the above mentioned factors and have some interesting implications for management and treatment of cancer.
Health and quality of life outcomes, 2024
Background Cancer survivors experience a decrement in health-related quality of life (HRQoL) resulting from the disease as well as adverse effects of therapy. We evaluated the HRQoL of cancer patients, stratified by primary cancer site, stage, treatment response and associated adverse events, along with its determinants. Methods Data were collected from 12,148 patients, sampled from seven purposively chosen leading cancer hospitals in India, to elicit HRQoL using the EuroQol questionnaire comprising of 5-dimensions and 5-levels (EQ-5D-5L). Multiple linear regression was used to determine the association between HRQoL and various sociodemographic as well as clinical characteristics. Results Majority outpatients (78.4%) and inpatients (81.2%) had solid cancers. The disease was found to be more prevalent among outpatients (37.5%) and inpatients (40.5%) aged 45-60 years and females (49.3-58.3%). Most patients were found to be in stage III (40-40.6%) or stage IV (29.4-37.3%) at the time of recruitment. The mean EQ-5D-5 L utility score was significantly higher among outpatients [0.630 (95% CI: 0.623, 0.637)] as compared to inpatients [0.553 (95% CI: 0.539, 0.567)]. The HRQoL decreased with advancing cancer stage among both inpatients and outpatients, respectively [stage IV: (0.516 & 0.557); stage III (0.609 & 0.689); stage II (0.677 & 0.713); stage I (0.638 & 0.748), p value < 0.001]. The outpatients on hormone therapy (B = 0.076) showed significantly better HRQoL in comparison to patients on chemotherapy. However, palliative care (B=-0.137) and surgery (B=-0.110) were found to be associated with significantly with poorer HRQoL paralleled to chemotherapy. The utility scores among outpatients ranged from 0.305 (bone cancer) to 0.782 (Leukemia). Among hospitalized cases, the utility score was lowest for multiple myeloma (0.255) and highest for testicular cancer (0.771).