Antioxidant activity and phytochemical screening of stem bark extracts of Grewia optiva Drummond ex Burret (original) (raw)
Related papers
Screening of antioxidant activity and phenolic content of 24 medicinal plant extracts
DARU Journal of Pharmaceutical …, 2008
Background: Antioxidants are vital substances which possess the ability to protect the body from damages caused by free radical-induced oxidative stress. A variety of free radical scavenging antioxidants are found in dietary sources like fruits, vegetables and tea. The purpose of this study was to evaluate the antioxidant activity of methanolic extracts of 24 selected plant materials (seeds or fruits), which are used by Iranian people as folk remedies and/or food supplements. Methods: The antioxidant activity was evaluated against linoleic acid peroxidation using 1,3-diethyl-2-thiobarbituric acid as reagent. At the same time the phenolic content of the extracts was determined using Folin-Ciocalteau reagent to evaluate their contribution to total antioxidant activity. Results: The antioxidant activity expressed as IC 50 ranged from 1.25 µg/ml in cucumber to 167.29 µg/ml in cardamom. Phenolic contents, expressed as gallic acid equivalents, varied from 21.76 mg/100g of the dried weight in linseed to 919.12 mg/100 g of the dried weight in Bishop's weed. No significant correlation was observed between antioxidant activity and phenolic content in the studied plant materials. Conclusion: The results of this study showed that there is no significant correlation between antioxidant activity and phenolic content of the studied plant materials and phenolic content could not be a good indicator of antioxidant capacity.
International Journal of Biosciences, 2024
Medicinal plants have been explored for the presence of phytochemicals and natural antioxidants for research and commercial utilization potentials. However, few studies were conducted on the selected medicinal plants' phytochemical profile and antioxidant contents. This study investigated the phytochemical profile, total phenolic, and total flavonoid contents of five methanolic leaf extracts of C. igneus, A. bilimbi, M. charantia, A. esculentus, and B. glabra. All five plants indicated the presence of carbohydrates, saponins, and alkaloids. A. bilimbi, M. charantia, A. esculentus, and B. glabra are potential sources of tannins. The total phenolic content of the extracts varied from 10.17±0.23 to 27.90±0.50 GAE/g. Whereas, the total flavonoid content of these plants ranges from 8.40±0.52 to 87.48±2.42 QE/g. The M. charantia leaves revealed the highest TPC while A. bilimbi yielded the highest TFC among the plants. The selected medicinal plants can be considered good sources of phytochemicals and natural antioxidants, phenolics, and flavonoids, which are the basis for the development and utilization of these plant leaves. The phytochemicals, phenolics, and flavonoids of these plants could be further isolated, purified, characterized, and utilized as antioxidants.
Applied Sciences
Given the important role of antioxidants in the cellular degeneration process, as well as the increased interest in recent years related to the use of natural antioxidants in therapy, the present study aims to investigate the antioxidant activity of a new pharmaceutical product containing natural antioxidants extracted from plant raw materials. In a first step, the product conventionally named “CILTAG”, containing a mixture in equal proportions of 10% hydroalcoholic extractive solutions of dried plant raw materials from Medicaginis herba, Trifolii pratense flores, Ginkgo bilobae folium, Myrtilli fructus, and Cynosbati fructus, was obtained. In the second stage, the antioxidant activity of the hydroalcoholic extractive solutions included in the pharmaceutical product was tested by chemiluminescence and electrochemical methods and by the superoxide dismutase (SOD) method. The electrochemical determination of the antioxidant capacity of hydroalcoholic extractive solutions was based on ...
A comparative study on the antioxidant activity of selected medicinal plant extracts
European Journal of Biotechnology and Bioscience, 2016
The ethanol and methanol extracts of, Prunus dulkis (Almond), Ficus racemosa (Audumbar), Kalanchoe pinnata (Panphutti), Ocimum gratissimum (Tulsi) were screened for their free radical scavenging property using ascorbic acid as standard antioxidant. Free radical sacvanging activity was studied using DPPH method. Highest antioxidant activity observed in Kalanchoe pinnata with 69.841% and 78.56% in ethanol and methanol extract respectively. In case of ethanol extract Ficus racemosa, and Ocimum gratissimum showed higher antioxidant activity as compared to other. In case of methanol extract Kalanchoe pinnata is at top. This present study proves that the plant extracts have considerable antioxidant property and further detailed studies and characterization of these plant extracts can contribute to their medicinal and pharmaceutical applications.
2014
The study was conducted to investigate the phenol, flavonoid content and antioxidant activity in some selected, traditionally used Indian medicinal plants in ethyl acetate, and screened for their antioxidant and free radical scavenging properties using Ascorbic acid and α-tocopherol as standard antioxidants. Antioxidant was determined using spectrophotometric methods. Antioxidant activities of extracts were expressed as percentage of DPPH radicals inhibition and IC50 values. The total phenolic content ranged from 35.25 to 224.49 mg/100g of dry weight of extract, expressed as Gallic acid equivalents.The total Flavonoids concentration varied from 6.86 to 126.24 mg /100g of dry weight expressed as rutin equivalents. Results suggested a good potential of phenolic and flavonoid compounds and antioxidant activity in Strychnosnux-vomica (IC50value42.60),SalaciaOblonga(IC50 value 42.94) Indigofera inctoria (IC50 value 40.64) Melothria maderaspatana(IC50 value 38.21 ) and Enicostemma littora...
International Journal of Nutrition and Metabolism, 2012
The objective of the present study was to find out the antioxidant potential of some wild edible plants, traditionally used by the local people of Meghalaya state in India and also to investigate the effect of solvent extraction system (aq. methanol and acetone) on the total phenolic, flavonoids and flavonols content, reducing power and antioxidant activity of the plants. The total phenol content varied from 3.31±0.10 to 27.67±0.16 mg/g in the aqueous methanol extract and 2.61±0.13 to 6.85±0.13 mg/g in the acetone extract of the plants. Flavonoids content were between 8.11±0.071 and 52.14±0.004 mg/g in aqueous methanol extract and varied from 1.22± 0.01 to 52.17± 0.01 mg/g in the acetone extract. 1,1diphenyl-2-picryl hydrazyl (DPPH) radical scavenging effect of the extracts were determined spectrophotometrically. The highest radical scavenging was observed in the aq. methanol extract of Gentiana pedicellata with IC 50 = 0.23±0.0007 mg dry material. The greater amount of phenolic compounds, flavonoids and flavonol content leads to more potent radical scavenging effect as shown by the aq. methanol extract of G. pedicellata. Flavonol content was observed highest in the aq. methanol extract of G. pedicellata (23.12 ±0.006 mg/g) and least in the acetone extract of Gynocardia odorata (0.09±0.008 mg/g). The reducing power of the extracts of the plants were also evaluated as mg AAE (ascorbic acid equivalent)/g dry material and highest reducing power (16.11 ± 0.03) observed in the aq. methanol extract of Bauhinia purpurea, which contain maximum amount of phenolic compounds (27.67±0.16 mg/g GAE). The results indicate that the type of extragent significantly influenced the antioxidant activity of these wild edible plants and could be utilized as potential source of natural antioxidant in the food or in pharmaceutical industry.
2018
Antioxidant properties of medicinal plants of Kandhamal district of Odisha have not reported, while these plants such as Nyctanthes arbor-tristis L. (NA), Tinospora cordifolia (Thunb.) Miers (TC), Phyllanthus niruri L. (PN), Andrographis paniculata (Burm.f.) Wall. ex Nees (AP), Lantana camara L. (LC), Mimosa pudica L. (MP), Justicia adhatoda L. (JA), Cuscuta reflexa Roxb. (CR), Cyperus rotundus L. (CyR), Piper nigrum L. (PiN), Ocimum sanctum Linn. (OS), Catharanthus roseus (L.) G.Don (CaR) and Clitoria ternatea L. (CT) are used to treat different ailments like malaria, rheumatoid, cold and cough, piles, diarrhoea and tooth ache etc. The present work aimed to evaluate the total phenolic and flavonoid contents as well as in vitro antioxidant properties of methanolic extract of medicinal plants. The total phenolic and flavonoid contents were determined by FolinCiocalteu and, aluminium chloride method with standard gallic acid and rutin respectively. Antioxidant activity was determined ...
Phytochemical Evaluation and Antioxidant Properties of Three Medicinal Plants Extracts
Medicinal & Analytical Chemistry International Journal
Objective: Medicinal plant over the years has been used to treat many diseases such as Diabetic, cancer, tumour, ulcers and bacterial. This study aimed at conducting the phytochemical analysis and in vitro antioxidant activities of the stembark extracts of selected medicinal plants (Leptadenia hastata, Barringtonia asiatica and Barringtonia racemosa). Material and Methods: All the plants were extracted by solvent maceration extraction methods. The Phytochemical analysis for alkaloids, phenolic compounds, tannins, flavonoids, coumarins, steroids, terpenoids, cardiac glycosides, essential oils, saponins and resins by using the standard methods. The in vitro antioxidant property was evaluated by assessing the DPPH˙ radical scavenging ability. Results: The preliminary Phytochemical evaluation of these plant species exhibited that the Dichloromethane extracts of Leptadenia hastata, Barringtonia asiatica and Barringtonia racemosa (Stem-bark) contain alkaloids, Sterols, Phenols, Flavonoids, Essential oil, Tannins, Terpenoid, Carbon hydrate, Cardiac glycosides, Saponins, Proathocyanidins, Coumarins, with Sterol and essential oil absent in the Leptadenia hastata and Coumarin in the Barringtonia asiatica and Barringtonia racemosa. The in vitro antioxidant activity of the species of Leptadenia hastata, Barringtonia asiatica and Barringtonia racemosa from five solvent extract of stem-barks have prominent antioxidant activities. Conclusion: This study suggests the potential source of natural antioxidant in Leptadenia hastata, Barringtonia asiatica and Barringtonia racemosa. Further research is highly recommended on the isolation of the bioactive compounds from these species and also to understand their mode of action in controlling various dreadful diseases.
The ancient use of the authors to search out for its inherent chemical characteristics responsible for such activity. The present study encompasses a complete analysis of the leaf portion moisture, vitamin C, minerals, phytochemicals and in ABTS + a comparative analysis w.r.t. the correspo already established. The principal components in general and the carotenoids in particular of the dioica deficiency. Although comparison to the fruits, but phytate content anaemic. The higher oxalate (+401.57%) and lower calcium (make it unsuitable for consumption for the people suffering with Ca leaf extract of and flavonoids (+664.84%) than the corresponding contents in the fruit part. Result showed that, the extract exhibited significant DPPH (16% more effective than the fruits) scavenging activities.
Screening of plant extracts for antioxidant properties
2011
Antioxidant properties of total methanol extracts from 54 species of 30 families were studied. DPPH (1,1-diphenyl-2-picryl hydrazyl) radical was used for evaluation of free radical scavenging. Among tested species, the extracts of Rumex crispus (radix), Rubus occidentalis (folia), Rumex alpinus (radix), Euphorbia helioscopia (herba) and Rubus idaeus (folia), exhibited the strongest activity. Signifi cant radical scavenging activity was found also in the extracts of Echium vulgare (herba), Plantago arenaria (herba), Viola tricolor (folia), Pyrus communis (folia), Sideritis montana (folia), Betula pendula (folia), Achillea critmifolia (herba), Santolina rosmarinifolia (herba), Morus alba (folia) and Erigeron canadensis (herba). Moderate activity was shown by extracts of Forsythia (folia), Bryonia alba (folia), Hepatica nobilis (folia), Plantago cornuti (folia), Maclura cochinchinensis (folia), Cihorium inhybus (herba) and Caltha palustris (herba).