A case report: a renal squamous cell carcinoma presenting as a nephrocutaneous fistula (original) (raw)
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International Surgery Journal
Squamous cell carcinoma (SCC) of the kidney is a rare entity. Often it is confused with Xanthogranulomatous Pyelonephritis (XGP), which is a chronic inflammatory disorder of the kidney, associated with the destruction of the renal parenchyma usually in the setting of an infectious process. A 76 year old male presented with right flank pain and vomiting. On examination, was found to have tenderness with localized guarding in the right flank. Investigations revealed a mass arising from the lower pole of the right kidney which was hydronephrotic and had features suggestive of stage III xanthogranulomatous pyelonephritis (XGP) with pyonephrosis and the presence of multiple calculi. Patient initially underwent a drainage of the pyonephrosis and subsequent nephrectomy. Histopathology revealed the presence of both XGP and SCC in the resected kidney specimen. Chronic nephrolithiasis is a predisposing factor for both XGP and SCC. XGP shares many characteristics with SCC in terms of both it...
National Journal of Laboratory Medicine, 2018
Primary squamous cell carcinoma of renal pelvis is a rare tumour associated with long standing renal calculi. We report here a case in which patient presented with pain abdomen and renal calculus with left pelvi ureteric junction obstruction and final diagnosis of primary squamous cell carcinoma of kidney was made only on histopathological examination. This case has been reported to highlight the silent and unusual presentation of common tumour at an uncommon site. Hence, a high degree of suspicion of squamous cell carcinoma should be made and considered as a differential diagnosis in patients presenting with history of renal stones.
2020
Background: Squamous cell carcinoma (SCC) which originated in the urothelium of the urological system is not uncommon; however, it is rare in the renal pelvis. Additionally, it is hard to be diagnosed without high clinical suspicion. Case summary: A-66-years old female presented with left loin pain for 6 years, hematuria, and fever for months. Examination revealed no abnormality apart from pallor and bimanually palpable left kidney. Her investigations showed normal renal function and anemia, Computer Topography for Kidney, Ureter, and Bladder (CT-KUB) revealed a large left renal pelvic stone with a hugely enlarged kidney with suspicion of xanthogranulomatous pyelonephritis (XGPN), with almost absent function of the left kidney in DTPA. She underwent Left trans-peritoneal radical nephrectomy. Post-operative histopathology result was moderately differentiated squamous cell carcinoma (T3, N0, M0). To our knowledge this was the first reported case in our hospital, we think that the trea...
Journal of Medical Case Reports
Background: Until now, few cases of pelvis squamous cell carcinoma in various renal anomalies have been reported. To our knowledge, primary squamous cell carcinoma arising from a pelvic ectopic kidney has never been described. In this report, we describe a case of renal pyelocalyceal squamous cell carcinoma in a patient with an ectopic kidney presenting with chronic pyelonephritis. Case summary: A 73-year-old Caucasian woman presented to our hospital with pyelonephritis symptoms. Abdominopelvic computed tomography revealed heterogeneous and irregular minimal contrast enhancement in the pelvic ectopic kidney parenchyma. Radiologists reported that the images were consistent with chronic pyelonephritis. A Tc-99m dimercaptosuccinic acid renal scan demonstrated a nonfunctioning right pelvic ectopic kidney. The patient underwent open simple nephrectomy via modified Gibson incision. The whole mass was a distended, saclike structure without any grossly visible renal tissue. Pathological examination showed renal pelvis squamous cell carcinoma 8 cm in diameter infiltrating into the renal capsule and perinephritic fatty tissue. The patient was staged as T4N0M1 renal pelvis squamous cell carcinoma. The patient was being treated in the intensive care unit for respiratory distress on the seventh day after the operation. By the first-month follow-up visit, the patient had died of acute respiratory distress syndrome. Conclusions: Although rare, renal pelvis squamous cell carcinoma should be considered in the differential diagnosis of a renal mass in patients who have renal anomalies and chronic pyelonephritis.
F1000Research, 2013
We present a case of Xanthogranulomatous pyelonephritis mimicking as a renal cell carcinoma. This was an elderly lady who presented with pyonephrosis due to urolithiasis. On evaluation she was found to have a space occupying mass in the right kidney. Further investigations revealed an enhancing tumor with renal vein thrombus and paracaval lymphadenopathy. Subsequent histopathology showed evidence of XGPN with no malignancy. This case report highlights the fact there are a number of imaging and clinical overlaps in the diagnosis, assessment and management of this entity.
Squamous cell carcinoma of kidney co-existing with renal calculi: a rare tumour
BMJ case reports, 2011
Squamous cell carcinoma (SCC) of urinary tract is a very rare tumour known to be associated with chronic renal calculi and infection. This tumour is highly aggressive and often detected at advanced stage with poor outcome. The authors describe a case report of a 62-year-old male patient who was diagnosed with right nephrolithiasis with non-functioning kidney. Histopathology revealed an unexpected co-existing SCC in renal pelvis. The present case highlights the careful search and use of newer imaging modalities in cases of long-standing renal calculi as they may have co-existing hidden malignancy which may change the treatment plan and prognosis.
Annals of African Medical Research, 2021
Squamous cell carcinoma of the kidney is a rare malignancy of the upper urothelium usually seen at advanced stage due to delay in diagnosis and or presentation. Mostly seen in patients with history of untreated chronic urolithiasis, chronic renal infection or analgesic abuse. A 46-years-old man who presented with right recurrent loin pain that radiates to the right groin of 10 years duration which worsened 2 weeks prior to presentation, he had history of recent haematuria, right loin pain, significant weight lost with associated history of untreated right renal calculi. General examination was not remarkable, ultrasound scan revealed a huge right renal mass with calculi. Intravenous urogram showed a non-functioning right kidney. Right radical nephrectomy was done, cut surface showed replacement of the renal parenchyma with greyish white tumour with stones in some blind calyxes. Histology revealed moderately differentiated squamous cell carcinoma of the right kidney. We report a case...
Squamous cell carcinoma of the kidney in a patient with staghorn calculi
Indian Journal of Case Reports, 2019
Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. The insidious onset of symptom and lack of any pathognomonic sign leads to delay in the diagnosis and subsequent treatment, resulting in grave prognosis for these patients. Here, we present a case of incidentally detected renal squamous cell carcinoma in a 71-year-old male with a staghorn calculus and Xanthogranulomatous pyelonephritis. The patient was treated with radical nephrectomy.
2021
Introduction: ChRCC is an uncommon type of renal carcinoma classified into typical and the less met eosinophilic variant. The latter is likely to be mistaken for other renal eosinophilic tumors, needing an extended immunohistochemical investigation, in order to exclude other oncocytic renal tumors. XGP is an unusual benign condition which may mimic renal cell carcinoma grossly and microscopically, being a rare chronic inflammatory disorder forming masses in the renal parenchyma.In this report we present a rare case of coexisting ChRCC and XGP in the same kidney. Case Presentation: A 51-year-old woman presented at the emergency unit with history of upper urinary tract infections, complaining about urinary frequency, and loin pain. An abdominal CT scan revealed lesion near the renal pelvis of the left kidney and the patient underwent left nephrectomy on a regular basis. The specimen we received included a brown and partially yellow tumor. The microscopical examination of the brown are...
Unusual case of nephrocutaneous fistula – our experience
Asian Journal of Urology, 2016
A rare case of nephrococutaneous fistula due to spontaneous expulsion of renal calculi is described. A 45-year-old man presented with urinary leakage from an ulcer over the left lumbar region for the last 3 months after a history of spontaneous expulsion of stones from this area. Ultrasonography abdomen revealed a small contracted kidney with multiple calculi in the kidney and renal pelvis, sinus tract from the lower pole of the left kidney with a ruptured calyceal calculus in the sinus tract. CT urography revealed a non excreting left kidney with multiple renal calculi, with hyperdense collection in the renal parenchyma extending to the subcutaneous tissue and left lung suggesting a xenthogranulomatous pyelonephritis (XGP). We performed a left-sided simple nephrectomy with excision of the fistulous tract. Histopathological examination revealed XGP. There have been a few case reports of XGP forming nephrocutaneous fistula in the back.