An Approach to Parallel Algorithms for Long DNA Sequences Alignment on Manycore Architecture (original) (raw)

Journal of Computational Biology, 2020

Abstract

The DNA sequencing process has evolved rapidly due to the development of new technologies and equipment capable of producing large amounts of sequencing data. Among these methods, PacBio stands out. The PacBio method uses single molecule real-time, generating sequence files composed by long reads. Storage and analysis of the data generated became a challenge ushering in the development of bioinformatic tools. One of these challenges is the alignment of these sequences. This article describes techniques and processes developed for long DNA sequence alignment using manycore architecture.

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