Review Article Hemangiopericytoma: A Case Report and Mini-Review (original) (raw)

Hemangiopericytoma– Rarest of the rare at uncommon site

IP Innovative Publication Pvt. Ltd., 2017

Hemangiopericytoma are vascular lesions are more commonly reported in the soft tissues when compared to reports in the hard tissues. These are considered to originate from the pericytes in the blood capillaries and hence can occur anywhere in the human body. The incidence of this entity among the other vascular lesion is only 0.1%. The most common locations reported are the brain, lower extremities, pelvic area, head, and neck. Hemangiopericytoma is most commonly located in the nasal cavity and paranasal sinuses in the head and neck region. Hemangiopericytoma are painless masses and may not have any associated symptoms but may turn symptomatic when other adjacent structures are affected. Though rare, their prognosis is better. This is because of the tendency to be less aggressive and not metastasizing. Here we attempt to report this pathology at zygomatic bone which is the rarest site of the occurrence of the vascular lesions as seen in literature.

Hemangiopericytoma of the neck

Head & face medicine, 2010

Hemangiopericytoma (HPC) is an exceedingly rare tumor of uncertain malignant potential. Approximately 300 cases of HPC have been reported since Stout and Murray described HPCs as "vascular tumors arising from Zimmerman's pericytes" in 1942. After further characterization, the WHO reclassified HPC as a fibroblastic/myofibroblastic tumor. Long term follow up is mandatory because the histologic criteria for prediction of biologic behavior are imprecise. There are reports of recurrence and metastasis many years after radical resection. The head and neck incidence is less than 20%, mostly in adults. We report herein a case of HPC resected from the neck of a 74-year-old woman, who presented in our department with a painless right-sided neck mass. The mass was well circumscribed, mobile and soft during the palpation. The skin over the tumor was intact and normal. Clinical diagnosis at this time was lipoma. A neck computer tomography scan showed a large submucosal mass in the ...

Clinical and Histopathological Aspects in Hemangiopericytoma

Acta Medica Transilvanica, 2021

Described as a type of soft-tissue tumour with malignant potential, hemangiopericytoma originates at the level of the pericytes, cells located in the walls of the capillaries. Although the etiology is not completely elucidated, it seems that the genetic factor plays an important role in the appearance of this type of tumour. Several cases with autosomal recessive transmission have been described in the literature. It is a formation that can occur at any age, but is more common after the age of 40. In fact, following multiple scientific studies, it has been concluded that the average age of affected people is somewhere around 45 years, while the survival rate at 10 years is 70%. Several cases have also been described in childhood (the percentage of occurrence at this age is between 5 and 10%). The sex incidence is equal. In what follows, I thought of presenting the case of a 90-year-old male person, diagnosed with an infiltrative and vegetative tumour formation located in the cavum, ...

Sinonasal hemangiopericytoma: A rare case report with review of literature

Journal of Oral and Maxillofacial Pathology, 2015

Hemangiopericytoma (HPC) is a rare tumor of uncertain malignant potential. Stout and Murray described HPC as "vascular tumor arising from Zimmerman's pericyte" in 1942.The World Health Organization (WHO) reclassified HPC as a fibroblastic/myofibroblastic tumor, after further characterization. HPC is found mostly wherever there is increased vascularity seen. The incidence of the tumor in head and neck area is only 15%, mostly seen in adults. We report here a case of HPC of a 22-year-old female, who presented to our department with a tender swelling in maxillary anterior region and the mass was well-circumscribed, sessile and soft on palpation. The skin over the tumor was intact and normal. The tumor was completely removed with wide surgical resection. The histopathological staining supported the diagnosis of HPC, this was further confirmed by immunohistochemistry (IHC) in which CD99 showed strong positivity.

Hemangiopericytoma like tumor - a diagnostic challenge

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2006

Haemangjopericytoma is a vascular tumour rarely seen in common practice, especially in head & neck. Hemangjopericytoma - like tumor is an even more rare entity and only 70 cases have been described arising from the nose & paranasal sinuses. The aim of this paper is to review the literature and highlight the ability of the tumor to masquerade as a less ominous, more commonly occurring benign growth of the region thereby making the diagnosis even more elusive.

Head and neck hemangiopericytoma in a child: case report

Sao Paulo Medical Journal, 2004

CONTEXT: Hemangiopericytoma is a relatively rare tumor, first described in 1942, with approximately 300 cases described in the literature to date. In most cases, it affects the trunk and lower extremities. The head and neck incidence is less than 20%, mostly in adults. We describe a case of malignant head and neck hemangiopericytoma in a child. TYPE OF STUDY: Case report. CASE REPORT: A twelve-year-old male patient noted the presence of a firm painless right-side retroauricular lymph node of 1 cm in diameter, which at first remained unchanged for six months, but subsequently enlarged progressively. He denied having had previous trauma at that site. In November 2000, he presented nasal obstruction and voluminous epistaxis that required hospitalization and blood transfusion. During dental treatment one month later, a cranial x-ray revealed bone alterations. A subsequent computed tomography scan showed an extensive lesion of soft tissue density that had invaded the maxillary fossa, eroding the skull base and middle and nasal fossa. The child was then referred to our service, where biopsy was performed, giving a diagnosis of hemangiopericytoma. Shortly afterwards, magnetic resonance imaging revealed that this lesion had undergone significant growth, while maintaining the same invasion pattern. The patient was submitted to conservative surgery in April 2001, with only partial resection of the tumor because of its extent. Histopathological examination of the specimen confirmed the presence of malignant hemangiopericytoma. Following the surgery, the patient presented fast regrowth of the lesion, with partial response to chemotherapy and radiotherapy.

Large hemangiopericytoma of the shoulder: A case report

Vojnosanitetski pregled, 2020

Introduction: Hemangiopericytoma is a rare tumor arised from the pericytes, contractile spindle cells that surround the capillaries and post-capillary venules. The tumor was found equally among males and females. Case report: We report a case of a 63-year-old female who presented a giant painful mass on her right shoulder that occurred one year before admission. Limited range of motion and a sense of tingling along the affected arm was present also. An irregular, oval-shaped mass, colored dark-red, with signs of necrosis was the maximal diameter of 14cm. Routine laboratory analyzes showed results within the range of referenced values. Lung X-ray and ultrasonographic examination of the abdomen showed no signs of secondary tumor deposits, and no osteo-muscular lesions in the affected region. Ultrasonographic examination of the neck and right axillary region showed no signs of regional metastases. The surgical excision of the entire tumor was performed, with the associated subcutaneous tissue and a part of fascia underneath. Results of the histopathological analysis confirmed the diagnosis of hemangiopericytoma. The specimen showed no signs or elements of the neoplastic tissue on the edges of the resection lines. 3 years after the operation, there was found no signs of tumor relapses, regional or systemic metastases. Conclusion: Considering that there are no official clinical guides and protocols for hemangiopericytoma management, as well as the occurrence of cutaneous and subcutaneous hemangiopericytomas is exceptionally rare, more extensive research in this field and more described cases are need to gain a better understanding of that issue.

Conventional Hemangiopericytoma: Modern Analysis of Outcome

Cancer, 2002

BACKGROUNDHemangiopericytoma (HPC) is a rare vascular tumor, and pathologic distinction from synovial sarcoma and solitary fibrous tumor is a significant problem due to shared histologic features. In the current report the authors defined the clinical behavior and prognosis for patients with HPC.Hemangiopericytoma (HPC) is a rare vascular tumor, and pathologic distinction from synovial sarcoma and solitary fibrous tumor is a significant problem due to shared histologic features. In the current report the authors defined the clinical behavior and prognosis for patients with HPC.METHODSBetween July 1982 and February 1998, 62 patients with a diagnosis of primary, recurrent, or metastatic HPC were identified from a prospectively maintained database. The pathology of all cases for which material was available (57 cases) was re-reviewed for histologic confirmation of the HPC diagnosis. Using strict pathologic criteria, including immunohistochemistry and electron microscopy, tumors from 25 of 57 patients qualified for the diagnosis of conventional hemangiopericytoma; those tumors formed the basis of the current report. Survival was determined by the Kaplan-Meier method.Between July 1982 and February 1998, 62 patients with a diagnosis of primary, recurrent, or metastatic HPC were identified from a prospectively maintained database. The pathology of all cases for which material was available (57 cases) was re-reviewed for histologic confirmation of the HPC diagnosis. Using strict pathologic criteria, including immunohistochemistry and electron microscopy, tumors from 25 of 57 patients qualified for the diagnosis of conventional hemangiopericytoma; those tumors formed the basis of the current report. Survival was determined by the Kaplan-Meier method.RESULTSAt the time of initial presentation, 19 patients had primary tumors, 3 had locally recurrent disease, and 3 had metastatic disease. The most frequent anatomic sites for HPC were the extremities, the pelvis, and the head and neck, accounting for 80% of the total cases. The median followup (n = 25) was 49 months (range, 1 to 160 months). The two and five year overall survival rates (n = 25) were 93% and 86% respectively. The disease-specific survival was 86% at last followup. Patients undergoing complete resection (n = 16) showed a 100% median survival at 60 months.At the time of initial presentation, 19 patients had primary tumors, 3 had locally recurrent disease, and 3 had metastatic disease. The most frequent anatomic sites for HPC were the extremities, the pelvis, and the head and neck, accounting for 80% of the total cases. The median followup (n = 25) was 49 months (range, 1 to 160 months). The two and five year overall survival rates (n = 25) were 93% and 86% respectively. The disease-specific survival was 86% at last followup. Patients undergoing complete resection (n = 16) showed a 100% median survival at 60 months.CONCLUSIONSAt present, complete tumor resection for patients with conventional HPC is recommended. However, considering the favorable outcome in this disease, the authors caution against performing operations that may potentially cause loss of function or are limb threatening. Cancer 2002;95:1746–51. © 2002 American Cancer Society.DOI 10.1002/cncr.10867At present, complete tumor resection for patients with conventional HPC is recommended. However, considering the favorable outcome in this disease, the authors caution against performing operations that may potentially cause loss of function or are limb threatening. Cancer 2002;95:1746–51. © 2002 American Cancer Society.DOI 10.1002/cncr.10867

Sinonasal hemangiopericytomas: Clinicopathologic and imaging findings

Ear, nose, & throat journal

Hemangiopericytomas are rare soft-tissue neoplastic lesions that can arise in any part of the body. They are mesenchymal tumors that account for 3 to 5% of all soft-tissue sarcomas and 1% of all vascular tumors. They originate in extravascular cells (pericytes). Some 15 to 30% of all hemangiopericytomas occur in the head and neck; of these, approximately 5% occur in the sinonasal area. We describe our brief retrospective review of 7 histologically proven cases of sinonasal hemangiopericytoma, and we discuss the imaging characteristics and clinical and pathologic findings in these patients.

Hemangiopericytoma: A rare case report

International Journal of Case Reports and Images, 2015

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties. Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. IJCRI publishes Review Articles, Case Series, Case Reports, Case in Images, Clinical Images and Letters to Editor.