A longitudinal study of distress (depression and anxiety) up to 18 months after radiotherapy for head and neck cancer (original) (raw)
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Anxiety and depression in patients with head and neck cancer: 6-month follow-up study
Neuropsychiatric disease and treatment, 2016
We aimed to assess psychiatric morbidities of patients with head and neck cancer (HNC) in a prospective study at pretreatment, and 3 and 6 months after treatment, and to compare their health-related quality of life (HRQL) between those with and without depressive disorders (depression). Patients with newly diagnosed HNC from a tertiary hospital were recruited into the study. They were assessed for psychiatric morbidities using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Their HRQL was simultaneously evaluated using the quality of life questionnaire of the European Organisation for Research and Treatment of Cancer with a specific module for head and neck cancer; and depressed and nondepressed HNC patients were compared by using the generalized mixed-effect model for repeated measurements. A total of 106 patients were recruited into this study. High rates of anxiety were found at pretreatment, but steadily declined o...
TEXILA INTERNATIONAL JOURNAL OF CLINICAL RESEARCH, 2016
Background: Potentially every aspect of life in cancer patients is found to be accompanied by a mental illness of anxiety and depression that affects the Physical relationships, Psychological wellbeing, Social relationships and the Environmental domain thereby reducing the QOL of cancer patients significantly. The advancements in cancer treatment have led to marked improvement in the survival rates of cancer patients; however, distressing symptoms of anxiety and depression arising due to treatment modalities are yet to be endured. The proposed study is considered valuable since it emphasized on the quality of life of cancer patients during their treatment for cancer symptoms as one of the possible outcomes. Because patients are the best source of information for QOL data, therefore inpatients for chemotherapy treatment and outpatients for radiotherapy treatment were recruited in the study to obtain a unique perspective on how QOL is defined, assessed, and perceived with respect to anxiety and depression during the treatment sessions. Objectives: The present study was conducted to assess the association and correlation of Anxiety and Depression with the domains of Quality of Life of cancer patients during inpatient Chemotherapy sessions or outpatient Radiotherapy sessions. The primary objective was to analyze the anxiety and depression levels (Recognition patterns) with their impact on QOL of cancer patients during chemotherapy or radiotherapy sessions. Methods: It was a Psychological intervention, non-experimental, cross-sectional, descriptive, observational, hospital-based evaluation study. The Research study was conducted at Medical and Radiation Oncology department of Dr. B.L. Kapur Memorial Hospital, New Delhi, India with total duration of 5 months (December 2015-April 2016). A convenient sample of 60 patients undergoing cancer treatment was selected in which 30 cancer patients were on chemotherapy (CT Group) and the other 30 cancer patients were on radiotherapy (RT Group). Data collection was performed by using 3 validated Psychological interventional tools: WHOQOL-Bref Questionnaire, Zung Self-Rating Anxiety scale (ZSAS) and Zung Self-Rating Depression scale (ZSDS). Appropriate statistical tests by using SPSS v.17 software were utilized to determine the significant association of anxiety and depression with QOL domains. Results: As a result, it was observed that 21(35%) males [6(20%) in Chemotherapy group and 15(50%) in Radiotherapy group] and 39(65%) females [24(80%) in Chemotherapy group and 15(50%) in Radiotherapy group] participated in the research study. Majority of the patients 32(53.34%) were found to be in the age range of 46-60 years. Out of the enrolled subjects, 33(55%) were undergoing Breast cancer treatment, 6(10%) were undergoing Head cancer treatment, and 21(35%) were undergoing Neck cancer treatment. Anxiety affected the Physical domain (p=0.007), and Environmental domain (p=0.036) in the Chemotherapy group; and Social domain (p=0.016) in the Radiotherapy group. On the other hand, Depression affected the Social domain (p=0.043) in Chemotherapy group; and Social domain (p=0.012) in the Radiotherapy group. Values of p < 0.05 were considered to be statistically significant. Conclusion: It is evident from the research study that Cancer patients on chemotherapy were more badly affected in some domains of Quality of life due to anxiety and depression as compared to the patients on radiotherapy treatment regimen. Moreover, it was observed that with the increase in Anxiety and Depression symptomatic levels, there was a marked decline in respective domains of the
Stress and Health, 2012
ObjectiveThe purpose of this study was to assess psychosocial changes at two particular moments: at cancer diagnosis and 2–4 weeks after having finished treatment.Material and methodsA total of 67 cancer outpatients were assessed in this study. The inclusion/exclusion criteria were as follows: ambulatory cancer patients aged 18 years or older and receiving medical treatment. Patients with a performance status <50 or with cognitive impairment (≥3 errors in the Pfeiffer Questionnaire) were excluded. The inclusion period ranged from 1 April 2005 to 30 April 2007. The scales used were the 14‐item Hospital Anxiety and Depression Scale (HADS), which has two subscales for anxiety (seven items) and for depression (seven items), the Quality of Life Short Form 36 Questionnaire, the Mental Adjustment Scale and the Medical Outcomes Study Questionnaire for measuring social support. All data were compared with sociodemographic and medical characteristics.ResultsPatients had higher levels of pr...
Head & Neck, 2019
Background: This study aimed at examining predictors of clinical anxiety and depressive symptoms in patients with head and neck cancer (HNC) at 3, 6, and 12 months post-diagnosis, with a particular interest in contextual and historical factors. Methods: Prospective longitudinal study of 219 consecutive patients newly diagnosed with a first occurrence of primary HNC, including psychometric measures, Structured Clinical Interview for DSM-IV Diagnoses (SCID), and medical chart reviews. Results: Point prevalence of clinical anxiety symptoms (Hospital Anxiety and Depression Scale-Anxiety subscale) was 32.0%, 21.9%, 12.1%, and 12.6% at baseline, 3, 6, and 12 months; and clinical depressive symptoms on the Depression Subscale was 19.4%, 21.9%, 13.5%, and 9.2%, respectively. Predictors of anxiety and depressive symptoms included upon diagnosis SCID major depressive or anxiety disorder, stressful life events in previous year, neuroticism, and levels of anxiety and depressive symptoms upon cancer diagnosis. Conclusions: This study emphasizes the predictive contribution of broader personal contextual and historical factors that increase psychological vulnerability in HNC and merit consideration. K E Y W O R D S anxiety disorder, cancer, head and neck cancer, major depressive disorder, oncology, stressful life events 1 | BACKGROUND Head and neck cancer (HNC) is generally diagnosed in advanced stage (50% in stage III or IV), 1 and 5-year survival rates range from 28% to 67% 2 (Canadian Cancer Society's Advisory Committee on Cancer Statistics, 2017). Depending largely on medical presentation and quality of life considerations, treatment typically consists of a combined surgery,
Patient’s perception of cancer-related depression/anxiety during their treatment
2017
Patients with cancer are emotionally affected during their cancer treatment course. Sometimes, patient’s psychological issues are overlooked during the actual disease treatment. Cancer patients are at a higher risk of developing anxiety and depression (A&D). A presumptive diagnosis of anxiety and depression was assessed based on a useful tool, the 14 item Hospital Anxiety and Depression Scale (HADS). Patient responses were assessed for the prevalence of anxiety and depression. In all, 102 patients were studied using the questionnaires of HADS. The demographic and clinical details were collected from patients. Breast cancer patients had the highest prevalence of anxiety (31.6%) and depression (32.4%) among all other cancer patients. Furthermore, cancer patients experienced more anxiety problems than depression. There is a significant relationship between gender and anxiety (p = .0144), with females experiencing more anxiety problems than males. 36.2% of patients did not discuss their...
Effect of Anxiety and Depression on Survival of Cancer Patients, a 13 Year Follow-up
Asian Pacific Journal of Cancer Care
Introduction: Anxiety and depression occur at a high rate in cancer patients. However, debate remains regarding the effect of anxiety and depression on cancer survival. Objective: This study aimed to determine the effect of anxiety and depressive symptoms on the survival of cancer patients. Methods: The subjects consisted of 112 cancer patients who attended the Oncology and Radiotherapy outpatient clinic Hospital Kuala Lumpur, Malaysia, in 1999. Anxiety and depressive symptoms were measured using the Hospital Anxiety and Depression Scale (HADS) questionnaire at inception. Information on patients’ mortality status for extended 13 years follow-up (in 2011) was obtained from the National Registration Department death records. Overall survival for each anxiety and depressive symptoms scores in HADS at 13 years was calculated using Cox proportional hazards regression analysis. Results: Cancer patients experienced more anxiety (83%) compared to depressive symptoms (40.2%). The mean (S.D.)...
Objective: Cancer is one among the life threatening diseases in present days it has biological, psychological and sociological impact on individual’s life. People living with this deadly disease have numerous psychological abnormalities like stress, depression and anxiety. The present study aimed to investigate the levels of anxiety and depression among cancer and non cancer patients. Methods:80 patients were randomly selected among them 40 were cancer patients and 40 were non cancerpatients. The Sinha’s Anxiety scale and Depression scale constructed by Karim & Tiwari was used to measure the anxiety and Depression among patients. For statistical analysis independent sample t-Test was applied. Findings: The results show significant differences between the mean scores of cancer and non cancer patients in respect to anxiety and depression. Conclusion: On the basis of our results we may concluded that cancer patients have higher levels of anxiety and depression than non cancerous patients.
Prevalence of depression and anxiety among cancer patients
Caspian Journal of Internal Medicine, 2014
Background: Depression and anxiety had negative effects on the quality of life of cancer patients, thus hospital anxiety and depression scale (HADS) is a useful instrument for screening these problems. This research was performed to assess the prevalence of their anxiety and depression. Methods: From 2012-2013, one hundred fifty patients with recent diagnosis of different cancers in Babol, Iran were assessed. A presumptive diagnosis of anxiety and depression was based on a four point 14-item HADS. The score of 0-7 means without clinical symptoms of anxiety or depression, 8-10 mild and 11-21 symptomatic anxiety or depression. The data were collected and analyzed. Results: Forty-four (29.3%) patients had mild anxiety, 25 (16.7%) symptomatic anxiety but mild and symptomatic depression were seen in 40 (26.7%) and 32 (21.3%) patients, respectively. There were significant relationships between anxiety, depression and the age group of the patients with higher frequency in older ages. There were significant relationships between anxiety and depression with the type of cancer and type of treatment. Breast and stomach cancer patients had the highest prevalence of anxiety and depression and the higher prevalence was observed in the patients who received chemotherapy as the single treatment. Conclusion: The results show that patients with breast and stomach cancer had the highest prevalence of anxiety and depression among all others cancer patients.
A study to assess the level of anxiety among cancer patient under chemotherapy
International Journal of Advanced Psychiatric Nursing
Anxiety is an emotion characterized by an exaggerated reaction to a certain situation. Many illnesses can cause anxiety. Cancer is a group of diseases involving the abnormal growth of cells with the ability to invade or spread to other parts of the body. These tumors are contrasted with benign, non-spreading tumors. Treatment methods, including chemotherapy, can increase anxiety in cancer survivors. This study aims to assess the anxiety level of cancer patients undergoing chemotherapy. Objectives To assess knowledge of level of anxiety among cancer patients To find out the significant association between socio-demographic variables and level of anxiety among cancer patients. Methods: Descriptive research design was used to assess the knowledge of level of anxiety patients in Saveetha Medical College and Hospital. The total number 50 study participants were participated who met all inclusion criteria. Purposive sampling technique used. Data collected by administering standardized questionnaire. The data oraganized and analysed by using descriptive and inferential statistics. Results: Among the 50 cancer patients (n=50) approached, 31(62%) were aged above 55 years, 38(76%) were male, 26(52%) were Hindus, 31(62%) had primary education, 44(88%) were married, 31(62%) had other occupation, 33(66%) belonged nuclear family and 28(56%) had family income of <10000. The result shows that 26(52%) had minimal to moderate anxiety 11(22%) were normal, 8(16%) had marked to severe anxiety and 5(10%) had most extreme anxiety. The mean score of anxiety among cancer patients under chemotherapy was 54.78 with standard deviation 9.88 With minimum score of 41.0 and maximum score of 78.0.