Management of malabsorptive bariatric surgery after cancer surgery for malignancies of the digestive apparatus (original) (raw)
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2016
Background: Routine preoperative upper gastrointestinal endoscopy (UGE) for bariatric surgery is still controversial. The optimal assessment for upper gastrointestinal tract in bariatric patients is not well defined although the prevalence of clinically relevant lesions found on the UGI is described in some observational studies. Methods: The present study highlights the clinical usefulness of preoperative UGE based on two real cases taking place in our practice. Results: Preoperative routine UGE prior to laparoscopic revisional surgery and gastric bypass surgery, showed adenocarcinoma in asymptomatic patients changing the initial surgical bariatric approach to an Oncological surgery. Conclusions: Preoperative routine UGE for bariatric surgery has a high diagnostic significance and low cost in relation to its effectiveness. Since, findings with this conventional exploration allow changes in the therapeutic strategy and also provide an adjustable treatment to every patient, preoperat...
Obesity surgery and malignancy: our experience after 1500 cases
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Obesity is a risk factor for cancer and is associated with increased mortality from a number of malignancies. We describe our experience with bariatric surgery patients with a history of malignancy and review the safety and outcomes of bariatric surgery in patients with a history of cancer. We performed a retrospective review of prospectively collected data from all patients diagnosed with a malignancy before, during, or after bariatric surgery. Data on weight loss, co-morbidities, and recurrence were collected. From July 1999 to February 2008, 1566 patients underwent bariatric surgery. Of these 1566 patients, 36 (2.3%) had a history of malignancy before they underwent bariatric evaluation and surgery, 4 (0.26%) were diagnosed with a malignancy during their preoperative evaluation, 2 of whom subsequently underwent bariatric surgery, and 2 had intraoperative findings suspicious for malignancy; bariatric surgery was completed in both cases. The evaluation revealed renal cell carcinoma...
Systematic Review and Meta-Analysis of the Impact of Bariatric Surgery on Future Cancer Risk
International Journal of Molecular Sciences
The study aimed to perform a systematic review and meta-analysis of the evidence for the prevention of future cancers following bariatric surgery. A systematic literature search of the Cochrane Library, Embase, Scopus, Web of Science and PubMed databases (2007–2023), Google Scholar and grey literature was conducted. A meta-analysis was performed using the inverse variance method and random effects model. Thirty-two studies involving patients with obesity who received bariatric surgery and control patients who were managed with conventional treatment were included. The meta-analysis suggested bariatric surgery was associated with a reduced overall incidence of cancer (RR 0.62, 95% CI 0.46–0.84, p < 0.002), obesity-related cancer (RR 0.59, 95% CI 0.39–0.90, p = 0.01) and cancer-associated mortality (RR 0.51, 95% CI 0.42–0.62, p < 0.00001). In specific cancers, bariatric surgery was associated with reduction in the future incidence of hepatocellular carcinoma (RR 0.35, 95% CI 0.2...