Erratum to “Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria” [World Journal of Vaccines Vol.4 No.3 (August 2014) 123-132] (original) (raw)
Related papers
Intussusception in children under five years of age in Enugu, Nigeria
The Pan African Medical Journal, 2021
Introduction intussusception is the invagination of a segment of the bowel into a distal segment. It occurs predominantly in infants worldwide. Following documentation of increased incidence after introduction of the first rotavirus vaccine (Rotashield, Wyeth-Lederle), it has become a standard recommendation to maintain surveillance for intussusception as newer rotavirus vaccines are introduced into EPI. Nigeria plans to introduce rotavirus vaccine in 2020. Pre-vaccine introduction surveillance will serve as a baseline to understand the epidemiology of intussusception in Nigeria. Methods from 2013 to 2017, prospective enrolment of under five children with intussusception was done following the WHO protocol and using the WHO case report form. Only children who met the Pan American Health Organization/World Health Organization (PAHO/WHO) protocol case definition for intussusception were enrolled. These children were monitored until discharge or death. Clinical features and outcome wer...
Retrospective Evaluation of Intussusception in Under-Five Children in Nigeria
World Journal of Vaccines, 2014
Background: Assessment of the safety profile of the new rotavirus vaccines in Africa requires base-line epidemiological data on intussusception. Hence, this study was aimed at describing the prevalence and associated factors of intussusception in under-five children in Enugu, Southeast, Nigeria. Methods: This was a retrospective descriptive study involving the sixty reported cases of intussusception in under-five children admitted in a hospital in Enugu between 2007 and 2012. Cases of intussusception were selected using the Brighton collaboration intussusception working group level I diagnostic criteria. Information sought from the patients' folders included demographic characteristics and clinical manifestations including history of previous rotavirus vaccination, duration of illness prior to presentation, diarrhoea, vomiting, passage of red currant jellylike stool, abdominal mass and distension, method of diagnosis, treatment option(s) employed and their outcomes. The data was analyzed using SPSS version 17.0. Results: The majority of the cases were aged less than one year (53; 88.3%) while the average incidence of intussusception was 0.1 per 1000. None of the cases had received rotavirus vaccinations. The common clinical presentations were vomiting, 55 (17.2%), passage of red currant stool 50 (15.6%), fever 50 * Corresponding author. B. N. Tagbo et al.
Evaluation of Intussusceptions in Under - Five Children in Aba Nigeria
American Journal of Pediatrics
Background: Intussusception remains a common cause of intestinal obstruction in infants and children. The operative treatment remains the main stay of treatment due to late presentation, long referral chain, paucity of knowledge about the disease condition by midwife and doctors. This study is intended to ascertain the pattern of presentation, management and outcome. Method: This is a prospective study of 48 children that was managed for intussusceptions at the Abia State University Teaching Hospital from November 2016 t0 November 2018. Structured proforma was opened for demography, clinical presentation, investigation, treatment modalities and outcome. Data was analysed using SPSS version 17 for proportions and percentages. Results: There were 24 boys and 24 girls aged 3 months to 13 months with a mean of 8months. The median duration of symptoms onset and presentation was 4 days {1 day to 14days}. Thirty-six patients {75%} presented after 48hours of onset of symptoms. A classic triad {bilious vomiting, bloody mucoid stool and abdominal mass} was present in over 40 patients {83%}. Ten patients did not pass bloody mucoid stool. Thirty patients {62.5%} had predisposing factors which included gastroenteritis and/or respiratory tract infection. 8 patients had hydrostatic saline reduction under ultrasound with success in six patients. Forty-two patients were operated {40 patients primarily and 2 patients following failed hydrostatic reduction}. Twenty-eight patients had resection and anatomises of ileocolic segment due to gangrenous bowel. Fourteen patients had manual reduction of intussuception with healthy bowel. Mortality was 8.3% {4 patients} from overwhelming sepsis and respiratory distress. Twenty patients had surgical site infection and 4 patients had incisional hernias. Conclusion: Late presentation was high in this series, however, emphasis on health education of mothers during antenatal visit that passage bloody mucoid stool by their child needs evaluation by a paediatrician will reduce late presentation morbidity and mortality in our patients.
2021
Introduction: Intussusception a pathological telescoping of a portion of bowel into an adjacent part. It is usually occur due to lymphoid hyperplasia in infancy and early childhood, where as in older children and adults, it is usually secondary to some identifiable pathological lead point. Intussusception has been reported in several studies to have a seasonal variation, with peaks coinciding with the peak incidence of viral respiratory tract infections and diarrheal disease. The currently approved rotavirus vaccines are associated with a slightly increased risk of intussusception as shown by some studies. Materials and Methods: This was a prospective case series study conducted in the Department of General Surgery, Government Medical College & Superfacility Hospital, Azamgarh. All children aged up to 12 years admitted with clinical diagnosis of intussusception and confirmed by USG were enrolled in the study. The study period was from January 2017 to December 2020. Patient details i...
Workshop on intussusception in African countries--meeting report
Vaccine, 2012
Rotavirus causes approximately 450,000 deaths annually among children less than 5 years of age worldwide, almost half of which occur in Africa. After the recent completion of successful trials of 2 new rotavirus vaccines, the World Health Organization has recommended these vaccines for all children worldwide. Because a previous rotavirus vaccine, Rotashield(®), was associated with intussusception, a form of intestinal obstruction among infants, the current rotavirus vaccines were tested in large clinical trials and found to be safe. However, due to the past Rotashield(®) experience, post licensure monitoring of intussusception is considered to be crucial after the introduction of future oral rotavirus vaccines. Thus, in planning for future introductions of rotavirus vaccine in Africa, a workshop of experts working on intussusception was convened by the World Health Organization in May 2004 in association with the Pan-African Association of Paediatric Surgeons (PAPSA) in Malawi. In b...
Background: Accurate estimates of the baseline incidence of childhood intussusception could help safety monitoring after introduction of rotavirus vaccines. Therefore, we studied the incidence of intussusception in the state ofQatar. Methods: We retrospectively reviewed cases of intussusception in children younger than 14 years. Children were treated between 2002 and 2012 at a single hospital inQatar. We analyzed information according to age, sex, clinical signs, diagnostic- and treatment-related characteristics, and length of stay. We calculated the national incidence of intussusception using census data. Results: A total of 106 children were diagnosed and treated for intussusception over 11 years. The male to female ratio of intussusception was 1.4:1. The most common symptom was bleeding per rectum (37%). One hundred andfour children with intussusception underwent diagnostic and therapeutic contrast enema, and 31.7% of patients underwent operative management. The length of stay was longer in patients who underwent operative reduction thanthat in those who did not. Conclusions: This is the first study to estimate the incidence of childhood intussusception prior to introduction of rotavirus vaccination in Qatar. A prospective surveillance system using a standardized case definition would be useful for examining the occurrence of intussusception in theArabicGulfarea and developing countries.
Clinical presentation and management of childhood intussusception in South Africa
Pediatric Surgery International
Purpose We assessed management and outcomes for intussusception at nine academic hospitals in South Africa. Methods Patients ≤ 3 years presenting with intussusception between September 2013 and December 2017 were prospectively enrolled at all sites. Additionally, patients presenting between July 2012 and August 2013 were retrospectively enrolled at one site. Demographics, clinical information, diagnostic modality, reduction methods, surgical intervention and outcomes were reviewed. Results Four hundred seventy-six patients were enrolled, [54% males, median age 6.5 months (IQR 2.6–32.6)]. Vomiting (92%), bloody stool (91%), abdominal mass (57%), fever (32%) and a rectal mass (29%) represented advanced disease: median symptom duration was 3 days (IQR 1–4). Initial reduction attempts included pneumatic reduction (66%) and upfront surgery (32%). The overall non-surgical reduction rate was 28% and enema perforation rate was 4%. Surgery occurred in 334 (70%), 68 (20%) patients had perfora...