Therapeutic Endoscopy during COVID-19 Pandemic: An Observational Study from Bangladesh (original) (raw)
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COVID-19 Disease and Comorbidity Effects on Dedicated Hospital in Bangladesh: A Prospective Study
Background: Coronaviral disorder (COVID-19) is a worldwide pandemic originating in Wuhan, China and spreading rapidly across the world and infecting human beings independently of age, sex, and race. There is still a lot to learn, given the nature of this infection. People with COVID-19 have reported a variety of symptoms, ranging from minor symptoms (e.g., common cold) to serious conditions such as bronchitis, pneumonia, severe acute air distress (ARDS) syndrome, multi-organ failure and even death. Comorbidity is a key component in the pandemic result COVID-19 which frequently results in fast and serious development, including death. Objective: The research examined the socio-demographic characteristics and characteristics of COVID-19 and assessed the effect of comorbidity on their hospital result. Methods: This observatory research was placed from April 2020 to September 2020 at Rajshahi Medical College, Rajshahi and CDM Hospital, Rajshahi (COVID-19) specialized hospital for a period of 06 months. All clinically suspected RT-PCR confirmation patients were included. Data were gathered via thorough patient history and then reviewed, consistency checked, and resulted modified. The coded data were examined using the SPSS software program after editing and coding. Results: The research included 627 patients, 552 of whom were in the covid ward and 75 in the ICU. 354 of Covid's (552) hospitalized patients were male (64.13%) and 198 (35.86%) were female (1:0.56%) patients. Young patients (age 19-50) were more impacted and hospitalized (62.86%), urban patients (52.61%) more susceptible than rural patients (47.28 percent). The primary symptoms were fever, cough and shortness of breath (63.04 percent, 45.47, and 42.39 percent, respectively). 44.20 per cent of patients with 55.79 per cent co-morbidities are not comorbid. Concerning co-morbidities. The major concurrent illnesses were hypertension (17.57%), followed by diabetes (15.94%), ischemic cardiac disease (05.60%), chronic blockage (05.60%), chronic renal disease (2.2%), heart attack (1.44%) and cancer (1.54 percent). (0.36%) of the population. A total of 75 patients, most of them seniors, required ICU treatment (64 out of 75). With regards to hospital outcomes, 96.74% (534 of the 552) and 45.34% (34 of the 75) of ICU admitted patients were released safely, whereas 03.2% and 54.66% of ICU patients hospitalized had expired. The number of fatalities among seniors was greater (n=43; 72.88 percent). Hypertension, diabetes and ischemic heart disease were often associated with dementia (42.37 percent, 37.28 percent, and 16.94 percent, respectively). Conclusion: The huge number of people with fever, poisoning and shortness of breath. The percentage of COVID-19 hospitalizations linked to mortality has remained high the elderly and those suffering from one or more comorbid illnesses. Elderly and comorbid patients should thus take all the required measures to prevent SARS CoV-2 infections.
Journal of Medical Science And clinical Research, 2020
The outbreak of the novel corona virus disease 2019 (COVID-19) began in Wuhan, China in December 2019. Since then, it has rapidly spread around the world. The clinical spectrum of COVID-19 pneumonia ranges from mild to critically ill cases. In this study, we tried to present details of patients admitted to the COVID-19 dedicated Mugda Medical College and Hospital in Dhaka, Bangladesh with laboratoryconfirmed COVID-19 and a definite clinical outcome (death or discharge) as of June 30, 2020. We conducted a retro-prospective study of 384 patients admitted with COVID-19. Epidemiological, demographic, clinical, treatment, and outcome data were obtained from patient charts and the hospitals' admission records using a structured questionnaire. Among them 384 of the PCR confirmed COVID-19 cases had an outcome of death (25.5%), transfer to other facilities (3.1%), discharge through palliative purpose (1.6%) or live discharge (67.2%). Males accounted for 52.9% of the study subjects and 44.4% of the survivors. Survival was significantly higher in females than in males (p ≤0.001). The most common symptoms on admission were fever (21, 70.6%) and cough (229, 59.6%), followed by shortness of breath (200, 52.1%), fatigue (152, 39.6%) and sore throat (141, 36.7%). In-hospital death was higher in patients with diabetes or hypertension. Moving forward, we hope to continue to deliver early and optimal care, limit community transmission, and tying the case fatality to the lower end of the known range.
COVID-19, Co-Morbidities and Its Impact on Prognosis in a Tertiary Care Hospital of Bangladesh
Journal of Medical - Clinical Research & Reviews
In December 2019, a new human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was discovered in Wuhan, China. Since then, the virus has spread over the world, affecting over 180 nations. SARS-CoV-2 has infected people of all ages, races, and genders, infecting both men and women and spreading at an alarming pace across communities. Given the virus's origin, much remains unknown; however, we do know that clinical presentations vary from a typical cold to more serious infections, including pneumonia, bronchitis, severe acute respiratory distress syndrome (ARDS), multi-organ failure, and even death. COVID-19 is thought to have a more fast and severe progression in people with underlying health issues or co-morbidities, frequently resulting in death. Methods: This retrospective study was conducted at Bangladesh's Tertiary care hospital. 534 patients were selected for this study. Medical history, age, gender, and co-morbidities (including Hypertension, ...
International Journal of Medicine and Public Health
SARS-CoV-2, commonly referred as COVID-19, has emerged as the most severe public health concern of the twenty-first century. Coronavirus usually is not very lethal to the persons who do not have any medical conditions, but it is fatal to people who have had past medical conditions that have often resulted in death. The objectives of this paper is to look at the effects of coronavirus on older diabetes patients, who are thought to be the ones who were affected the most by COVID-19. This research used a qualitative approach and was descriptive in nature. The researcher has purposefully chosen three areas in Dhaka city as the studies fixate: Shahbag, Khilgaon, and Rampura. Data was gathered using qualitative methods such as focus group discussion and key informant interviews. According to the study's findings, COVID-19 had a serious effect on older adults with diabetes. The number of patients at the hospital had significantly decreased. Despite the fact that hospitals were equipped to provide treatment and care, patients' mobility was limited. Many people preferred virtual consultation or telemedicine to face-to-face consultation and care. Doctors encouraged individuals to connect digitally, which is both safe and feasible in the face of the global pandemic. The expense of a diabetic patient rose, according to the majority of respondents. According to the findings, the pandemic is spurring new diabetes-care delivery methods. Many structural flaws were exposed as a result of Covid-19, paving the door for additional improvements in healthcare delivery in the study area.
Molecular Mechanism Research, 2023
Background: The COVID-19 pandemic has had a profound impact on global health, with millions of individuals affected by the viral infection. Among the vulnerable populations, diabetic patients face a higher risk of severe illness and complications when exposed to the SARS-CoV-2 virus. Bangladesh, like many other countries, has witnessed a significant number of COVID-19 cases, raising concerns about the management and outcomes of diabetic patients during this pandemic. This study highlights clinical and demographical experiences in hospitalized and non-hospitalized covid-19 patients in Bangladesh. Methodology: This descriptive crosssectional study was from May 2021 to August 2022. Five selected government hospitals and six private hospitals located in the Dhaka Division were included in this study. The diagnosis of SARS-CoV-2 infection was confirmed by real-time reverse transcriptase polymerase chain reaction (RT-PCR) test. Results: Data of 416 nonhospitalized patients with COVID-19 were recorded and analyzed. The mean age of the patients was 44.42 ± 14.20 year with 336 males and 80 females. Comorbidities were present of which hypertension 38.5%, diabetes 32.7%. A significant proportion of patients had symptomatic such as fever 92.3%, dry cough 88.5%, loss of taste 48.07%, loss of smell 50.96% was the most common. Majority of the patients were managed with supportive treatment with paracetamol 38.46%, antihistamine 76.9%, oral vitamin-c 83.65%, and antibiotics 67.30%. It took an average of 12-14 days for them to become negative. And hospitalized patients, of whom 131 were males and 53 were female. Overall mean age was 45.12±13.80 years. They have some kind of comorbidities present like diabetes mellitus 45.65%, hypertension 56.52%, hyperlipidemia 17.39%, coronary heart disease 21.73% etc. In addition, they have taken some medicine as per the doctors advise such as paracetamol 45.65%, antihistamine 63.04, oral vitamin c 69.56%, antibiotics 58.69%, antifungal 45.6% and oxygen therapy 28 (15.21%). Some changed laboratory parameters were observed. Conclusion: We concluded that laboratory results from nonhospitalized patients did not show any major alterations or abnormalities, but laboratory results from hospitalized patients did show substantial changes. There is a post-COVID-19 tiredness warning for them.
Objectives: The COVID-19 pandemic has severely impacted health-care delivery globally, especially for non-COVID diseases. These cases received suboptimal attention and care during the pandemic. In this observational cohort study, we have studied the impact of the COVID-19 pandemic on various aspects of medical and surgical practices. Material and Methods: This observational, cross-sectional cohort study was performed on the data of a 710 bedded, multispecialty, and tertiary care corporate hospital of the national capital of India. The data of the pandemic period (April 1, 2020-March 31, 2021) were divided into three main groups and were then compared with the patient data of the preceding non-pandemic year (April 1, 2019-March 31, 2020) of more than six hundred thousand cases. Results: From the data of 677,237 cases in these 2 years, we found a significant effect of COVID-19 pandemic on most spheres of clinical practice (P < 0.05), including outpatient attendance and surgical work. The specialties providing critical and emergency care were less affected. Although the total hospital admissions reduced by 34.07%, these were not statistically significant (P = 0.506), as the number of COVID-19 admissions took place during this time and compensated for the drop. Conclusion: The COVID-19 pandemic has significantly impacted health-care delivery to non-COVID cases across all the major medical and surgical specialties. Still, major urgent surgical and interventional work for cases was undertaken with due precautions, without waiting for the ongoing pandemic to end, as the delay in their treatment could have been catastrophic.
Bangladesh Journal of Medical Science, 2020
Corona virus Disease 2019 (COVID-19) is a severe acute respiratory infection caused by corona virus-2 (SARS-CoV-2). It originated from Wuhan city of China in December 2019 and spread like a wild fire to the entire globe and was declared as global pandemic by WHO on March 11, 2020. With no available cure and vaccine, this disease has taken a mammoth toll on the human life; therefore, SMS (‘Social Distancing’, use of ‘Mask’ and regular hand washing with ‘Soap’) has emerged as a sole tool to prevent its spread. The Indian government declared the first lockdown from March 25th 2020 with subsequent second, third and fourth lockdowns up to 31st March 2020 to decrease the disease transmission and flatten the disease transmission curve. Aligarh Muslim University is one of the prestigious central and residential universities in India. It is located in Aligarh district adjoining national capital region. The university has an attached tertiary care ‘Jawaharlal Nehru Medical College Hospital’. ...
Euroasian Journal of Hepato-Gastroenterology, 2020
Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared as pandemic by World Health Organization (WHO) with increasing morbidity (more than 4.6 million patients) and mortality (300,000 deaths). The worldwide target of management COVID-19 is to reduce complications with available management options; this become highly variable from country to country and even within different regions of the same country. Aim and objective: This observational prospective study represents a single center study in which all patients in this cohort received almost similar medicines and care. Materials and methods: All patients in this cohort (N: 32) were positive for SARS-CoV-2 by polymerase chain reaction (PCR) with variable presenting symptoms. The management strategy included Standard of Care (SoC) and administration of hydroxychloroquine and doxycycline. Out of 32 patients, 9 patients also received favipiravir. All patients were followed until they were discharged after negativity of SARS-CoV-2 confirmed by PCR on two consecutive occasions taken within 2 days. Results: No death has been recorded in this cohort of 32 patients within the study period. The average hospital staying duration was 13.9 days with a range of 8-21 days. All patients were discharged with improvement of subjective symptoms and SARS-CoV-2 negativity. The vital signs (pulse, blood pressure) as well as and levels of electrolyte and blood counts were within normal and acceptable ranges at the time of discharge. Conclusion: The study presented here provide and evidence of a real-life situation of management of limited numbers of COVID-19 patients at a tertiary center of Bangladesh. This study inspires optimism that proper diagnosis, establishment of effective inclusion and exclusion criteria, ensuring application of proper SoC with drugs available in Bangladesh may be a practical option for management of COVID-19 in the country.
BIRDEM Medical Journal
Background: Patients with chronic kidney disease (CKD) are at increased risk for infection because of immunosuppressed state. CKD is an independent risk factor for poor outcome in coronavirus disease 2019 (COVID-19). This study was designed to describe clinical and laboratory parameters of COVID-19 patients with preexisting CKD. Methods: This cross-sectional study was conducted in the Department of Nephrology, BIRDEM General Hospital from July to December 2020. Hospitalized adult patients with CKD not yet on dialysis, who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcriptase polymerase chain reaction (RT-PCR), irrespective of symptoms were included in this study. RT-PCR negative cases were excluded. Results: Total patients were 40 (mean age 58.3 years, 52.5% male). Common comorbidities were diabetes mellitus (92.5%), hypertension (67.5%) and ischaemic heart disease (27.5%). Fever, cough, shortness of breath, headache and fatigue we...
Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh
Euroasian Journal of Hepato-Gastroenterology
Background and aim: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing during last 5 months causing millions of COVID-19 patients and hundreds of thousands of deaths. Bangladesh, a country of 170 million people, is not an exception regarding COVID-19; it has reported several thousand COVID-19 patients with several hundred of deaths. This observational study has been planned to assess the scope and limitation of management strategy against COVID-19 patients in a medical college hospital of Bangladesh with available drugs in a real-life situation. Materials and methods: All patients in this cohort (N: 33) were positive for SARS-CoV-2 by polymerase chain reaction (PCR) and they attended the hospital with variable presenting symptoms those ranged from cough and fever to respiratory distress and pneumonia. As per the protocol, the patients were regularly evaluated for several parameters of COVID-19-related pathology. Before discharge, they were checked for SARS-CoV-2 for 2 consecutive times. The management strategy included standard of care (SoC) and administration of hydroxychloroquine and azythromycin, available in Bangladesh. Results: Out of total 33 patients, 1 patient died at day 4 day after admission. Two patients developed severe complications and were referred to tertiary hospital in Dhaka (2 and 3 days after admission), the capital of Bangladesh, where they recovered and were discharged from hospital after being SARS-CoV-2 negative. The rest 30 patients were discharged from the medical college hospital after being negative for SARS-CoV-2 in two subsequent assessments and improvement of their COVID-related symptoms. The average hospital stay of these patients was 14.5 days with a range of 10-24 days. Conclusion: It seems that most of the COVID-19 patients may be adequately managed by standard of care management with drug support. However, early diagnosis and hospitalization with adequate care may be important variables for better survival. These factors may be properly ensured if the patient burden remains at a palatable level in forthcoming days in Bangladesh.