The Desire of Infertile Patients for Multiple Births: A Re-Examination with Updated Societal Guidelines and an Evolving Infertility Insurance Landscape (original) (raw)

2020, Fertility and Sterility

Between January 1976 and August 2001, endometrial samples from 87 women who underwent endometrial biopsy for abnormal uterine bleeding at the authors' institution were reported as "inadequate." The medical records of 76 women were suitable for review and were used to investigate the negative predictive value of inadequate endometrial specimens. Mean follow up was 26 months (range, 0-60 months). Follow-up management varied from observation to further diagnostic biopsy or ultrasound, or to treatment with hysteroscopy, dilation and curettage, or hysterectomy (Fig. 1). Fifty-five women were postmenopausal and 21 were premenopausal (mean age, 55 years). Follow-up tissue diagnoses were available for 37 women. In these patients, there was 1 histologic diagnosis of complex hyperplasia without atypia. Among the 38 women without follow-up tissue diagnoses, there were no reports of further bleeding.