The effects of a six-week supervised multimodal exercise intervention during chemotherapy on cancer-related fatigue (original) (raw)
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BMJ (online)
To assess the effect of a multimodal group exercise intervention, as an adjunct to conventional care, on fatigue, physical capacity, general wellbeing, physical activity, and quality of life in patients with cancer who were undergoing adjuvant chemotherapy or treatment for advanced disease. Randomised controlled trial. Two university hospitals in Copenhagen, Denmark. 269 patients with cancer; 73 men, 196 women, mean age 47 years (range 20-65) representing 21 diagnoses. Main exclusion criteria were brain or bone metastases. 235 patients completed follow-up. Supervised exercise comprising high intensity cardiovascular and resistance training, relaxation and body awareness training, massage, nine hours weekly for six weeks in addition to conventional care, compared with conventional care. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), Medical Outcomes Study Short Form (MOS SF-36), Leisure Time Physical Activity Questionnaire, m...
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the e!ectiveness of exercise on overall HRQoL outcomes and specific HRQoL domains (e.g. physical, psychological, economic, social, and spiritual well-being, and key disease and/or treatment symptoms such as sexual functioning, neuropathy or cognitive changes, and chronic fatigue) among adult persons with cancer during active treatment (excluding those who are terminally ill and receiving hospice).
An Exercise Intervention for Cancer Fatigue
2018
Cancer related fatigue (CrF) is a debilitating side effect reported by cancer survivors, often lasting years following treatment. Although some evidence exists of a beneficial effect of exercise on CrF, there are critical shortcomings in the literature. Previous exercise rehabilitation studies did not specifically target fatigued cancer survivors. Most studies also lacked an appropriate control condition to isolate the effects of exercise per se. This thesis is comprised of three studies. The first study, an efficacy study, compared the effects of a 10-wk exercise intervention to a health education intervention on fatigue, fitness and psychological health outcomes in post-treatment cancer survivors with documented fatigue. The 37 post-treatment cancer survivors (33 females, 20 severe fatigue, 11 moderate fatigue, 30 breast cancer, aged 55±2 y, 2.3±0.3 y since treatment; mean±SEM) were allocated to an exercise group (EXG, n=19) or health education comparison group (HEG, n=18). The in...