DNA Methylation Profile at the DNMT3L Promoter (original) (raw)

Epigenetic events play a prominent role during cancer development, with almost all cancer types showing aberrant DNA methylation. This study examines the DNA methylation status at the DNMT3L promoter in normal and cervical cancer samples, revealing significant DNA methylation differences. Specifically, the DNMT3L promoter lost DNA methylation in 14 out of 15 cervical cancer samples analyzed, highlighting its potential as a biomarker for cervical cancer and suggesting a possible role in cancer development.