A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19 (original) (raw)

Parvovirus B19 associated papular-purpuric gloves-and-socks syndrome

… Turkish journal of …, 2006

The papular-purpuric gloves-and-socks syndrome (PPGSS) is a disease characterized by an itching erythema and edema of the hands and feet, oral mucosal lesions and fever. It may be caused by various agents. Parvovirus B19 has been implicated as the etiological factor in most cases. Here we report a case of PPGSS in a nine-year-old previously healthy girl with papular and petechial lesions on her peroral area and trunk, and primarily on the dorsal areas of her hands and feet. Serologic study confirmed the acute infection by parvovirus B19. We believe that our case is worthy of particular attention because of the rarity of the disease in the pediatric age group and because it is the first documented case of PPGSS in Turkey.

Papular-purpuric "gloves and socks" syndrome due to parvovirus B19 infection in childhood [letter]

Pediatric Dermatology, 1998

Papular purpuric gloves and socks syndrome (also known as gloves and socks syndrome) is a relatively newly described viral dermatosis with unique characteristics. These characteristics typically include an erythematous, papular, or petechial rash and edema in an acral distribution, often with associated mucosal lesions, arthralgias, and fever. We present a case of papular purpuric gloves and socks syndrome in a 46-year-old patient with acute parvovirus B19 infection, review the descriptive literature, and summarize our evolving understanding of this disease.

Papular-purpuric “gloves and socks” syndrome: Polymerase chain reaction demonstration of parvovirus B19 DNA in cutaneous lesions and sera

Journal of the American Academy of Dermatology, 1999

We report a typical case of papular-purpuric "gloves and socks" syndrome (PPGSS) in which primary infection by parvovirus B19 was demonstrated by seroconversion to this virus; parvovirus B19 DNA was also identified by polymerase chain reaction (PCR) methods in the sera of the patient and in the cutaneous biopsy specimen, both taken 4 days after the onset of clinical manifestations. To our knowledge, this is the fourth published case in which parvovirus B19 DNA has been recovered from the skin by PCR. Serologic studies and PCR investigations in cutaneous biopsy for other viruses including herpes simplex virus types 1 and 2, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpesvirus 6, 7, and 8 were negative. Clinically, our case presented some additional features, which have not been previously described in cases of PPGSS, namely dysuria with vulvar edema and erythema, and unilateral petechial rash on the breast. The histopathologic findings of our case were nonspecific and consisted of an interface dermatitis with slight vacuolar degeneration at the dermoepidermal junction and a superficial perivascular inflammatory infiltrate mostly composed of lymphocytes, with numerous extravasated erythrocytes. We review the cases of PPGSS published in the literature with respect to the different viruses that have been proposed as etiologic agents and conclude that acute infection by parvovirus B19 is the only one that has been adequately proved. aAm Acad DermatoI1999;41:793-6.)

Petechial glove and sock syndrome caused by parvovirus B19

Journal of the American Academy of Dermatology, 1992

The petechial glove and sock syndrome is a recently described febrile dermatosis characterized by acral pruritus, edema, pain, petechiae, and an enanthem of petechiae and erosions; these features suggest a viral origin. We report a typical case in a 36-year-old woman. IgM antibodies to human parvovirus B19 (PVB19) were present, and acute and convalescent IgG antibodies demonstrated seroconversion, which suggested recent infection with PVB 19. Results of tests for other viral and bacterial agents were negative. These results strongly implicate PVB 19 as an etiologic agent in the petechial glove and sock syndrome. (J AM ACAD DERMATOL 1992;27:835-8.)

Papular Purpuric Rash Due to Parvovirus B19 with Distribution on the Distal Extremities and the Face

Clinical Infectious Diseases, 2002

We describe 3 patients who presented with a distinctive clinical picture of the purpuric rash called "gloves-and-socks syndrome" which was characterized by an acral distribution of the rash that involved not only the distal part of the extremities but also the chin and perioral area. Serologic analysis for parvovirus B19 yielded positive results. Parvovirus B19 should be included in the evaluation of febrile purpura.

Parvovirus B19 infection presenting concurrently as papular– purpuric gloves-and-socks syndrome and bathing-trunk eruption

Parvovirus B19 infection can cause a wide range of cutaneous manifestations, including papular–purpuric gloves-and-socks syndrome (PPGSS) and petechial bathing trunk eruption. We report a case of an immunocompetent woman with a primary parvovirus B19 infection presenting as concurrent PPGSS and petechial bathing trunk eruption. Parvovirus B19 seroconversion was confirmed several days after the onset of the clinical manifestations. The coexistence of these two cutaneous manifestations of primary parvovirus B19 infection has rarely been reported in the literature. It is important to recognize parvovirus B19 infection early, based on the cutaneous manifestations, to avoid potentially serious systemic complications in susceptible individuals.