A Rare and Interesting Case of Mediastinal Fibromatosis (original) (raw)

Patient With Slow-Growing Mediastinal Mass Presents With Chest Pain and Dyspnea

Chest, 2016

A 52-year-old white woman presented with severe pain over the right upper abdomen and nonpleuritic, right-sided, lower chest-wall pain. Her pain had progressively gotten more frequent and severe over the last 5 months. It was also associated with a nonexertional, pressure-like sensation in the central chest. The patient denied any shortness of breath, fevers, cough, or any sputum production. She was taking levothyroxine for hypothyroidism and was a 30-pack-year current smoker; there was no history of drug abuse or occupational exposure. Previous chest radiographs dating back to 5 years consistently showed an elevated right-sided hemidiaphragm without any infiltrates or effusions; cardiomediastinal structures were unremarkable. She had not had a previous workup for these abnormal findings.

CASE REPORT: Extralobar pulmonary sequestration presenting a paravertebral mass with extensive fibroadenomatous change in an adult

Basic and Applied Pathology, 2010

We report herein an unusual case of pulmonary extralobar sequestration (ELS) showing fibroadenomatous change. It was incidentally found in a 41-year-old woman presenting with a paravertebral mass on chest radiography during a routine health check-up. Computed tomography reveled a 3.6 cm, well-defined solid mass in the paravertebral region. The resected mass was predominantly solid and well-covered by pleura with irregular cystic spaces. Microscopically, it showed a unique fibroadenomatous change, dilated bronchiolar structures and prominent fibrous stroma. In the periphery of the mass, a small portion of the lung with normal alveolar structure was noted. The lining epithelium showed reactivity for thyroid transcription factor-1 by immunohistochemical staining.

Vocal Hoarseness and a Subglottic Mass

Journal of Investigative Medicine High Impact Case Reports, 2015

We report a patient with tracheopathia osteoplastica (TPO), a rare or perhaps underrecognized disorder, detected in approximately 1 in every 2000 to 5000 patients who undergo bronchoscopy. TPO is marked by proliferation of bony and cartilaginous spurs leading to airway stenosis. Multiple submucosal cartilaginous and osseous nodules can develop in the respiratory tract and may involve the entire trachea and mainstem bronchi. Symptoms may range from a completely silent condition to life-threatening respiratory failure and diagnosis is made based on radiological and bronchoscopic findings. Although the etiology has not been established, TPO can be familial and is sometimes associated with chronic inflammation, such as seen with rheumatic diseases. This case highlights the need for understanding TPO so that it can be differentiated from potentially serious conditions such as necrotizing granulomatous diseases, invasive infections, and cancer.

A 71-yr-old male with increasing dyspnoea, cough and an intrathoracic mass

European Respiratory Journal, 2003

A 71-year-old White male was referred to the Martini Hospital for evaluation of progressive shortness of breath, tiredness, a nonproductive cough and night sweats. Until the beginning of his complaints a few weeks before, he felt healthy and skated 40 km per week. His appetite was good, he had not lost weight, had no skin or joint disorders and no thoracic pain.

An Unusual Intrathoracic Mass in a Patient With Developmental Delay

Intrathoracic masses may be detected asymptomatically or cause symptoms due to the compression of surrounding normal tissues or organs. Mediastinal masses may be encountered at practically any age and may result from a myriad of causes, and are sometimes detected in otherwise asymptomatic patients. Mediastinal masses are less frequently detected in pediatric patients compared with adult patients, and the spectrum of mediastinal masses in children differs from those encountered in adults. The approach to a mediastinal mass requires careful assessment of the location, appearance, and relationship of the mass to the surrounding structures. The differential diagnostic considerations for mediastinal masses can be broad, but careful assessment coupled with additional directed testing can often narrow the differential considerations. We report the case of a 14-year-old boy with an incidentally detected mediastinal mass at chest radiography that, on further evaluation , led to a very unusual diagnosis. This report highlights the differential diagnoses that were considered for this mediastinal mass and the diagnostic evaluation that led to the final diagnosis.