Storms in COVID-19 (original) (raw)

RGUHS journal of medical sciences, 2021

Abstract

Severe Acute Respiratory Syndrome SARS novel coronavirus 2 nCoV2 has been declared as a pandemic by the WHO and it is implicated in varying degree of mortality and morbidity among different nations. Several studies have shown that susceptibility to cytokine storm is responsible for differences in mortality and morbidity. Interleukin-6 IL-6 has been implicated strongly for the cause of cytokine storm in COVID-19 infections. But it is unclear about the cause for the severity of COVID-19. Recent studies have shown that bradykinins one of the peptides are also implicated in storm leading to severe complications among the infected. Hence this review article is focused on role of cytokines and bradykinins in causing storms in COVID-19.

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