Implementation of sonication and feedback control strategies for targeted hyperthermia in prostate with a commercial MR-guided endorectal ultrasound ablation array (original) (raw)

This study presents a novel approach for implementing targeted mild hyperthermia (HT) in prostate treatment using a commercially available MR-guided endorectal ultrasound (ERUS) system. The research involves extensive numerical simulations and subsequent implementation of HT-specific beamforming and control strategies, demonstrating the system's capability to deliver conformable HT to defined cancer volumes through effective temperature modulation. Results indicate successful sonication with sustained temperature increases suitable for long-duration applications, offering potential clinical advantages in focal radiotherapy and chemotherapy.