Epidemiological Characteristics of Patients with Multiple Sclerosis in Kermanshah, Iran in 2012 (original) (raw)

2013, Journal of Mazandaran University of Medical Sciences

Background and purpose: Multiple Sclerosis (MS) is the most common neurological disorder in young adults that leads to their disability. This study aimed to evaluate the epidemiological characteristics of MS in Kermanshah, Iran in 2012. Materials and methods: In this descriptive study, total of 448 MS patients in Kermanshah were studied. Data for this study were derived from patients' files, whom were members of MS Society in Kermanshah. SPSS software was used for this research. Results: The prevalence of MS in Kermanshah was 43.3 in 100,000 population, that the rate for women and men were 65.6 and 21.9 in 100,000 population, respectively. The onset for this disease was 30.8 years and the agegroup of 30-34 years devoted the highest proportion of its morbidity to itself (20.1%). 1.2% of patients had familial history of MS in first-degree relatives. Sensory disturbances are the highest manifestations of MS onset (24.1%). 42.6% of patients have been diagnosed within 6 months after the onset of symptoms. Conclusion: According to the results of this study, there was a high prevalence of MS in Kermanshah and the incidence of this disease was more probable among youths (especially in women). Furthermore, more comprehensive studies are required on epidemiological data and risk factors of MS.

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The Impact Of Chronic Diseases On The Quality Of Life Among The Elderly People In The East Of Tehran

Payavard Salamat, 2012

Background and Aim: Increase in life expectancy is associated with noncommunicable diseases. This study is aimed to survey the effect of chronic diseases on the quality of life among the elderly people in elderly care centers in the East of Tehran in 2011. Materials and Methods: This is an analytical study in which 424 people were randomly selected. They were members of elderly care centers and were 60 years of age or higher. The data collection instruments were a standard quality-of-life questionnaire(SF36) and a chronic diseases record checklist. The data were collected in an interview. For data analysis purposes, Independent T-Test, ANOVA, and Pearson correlation coefficient were used. Results: The mean age of participants was 67.34±7.16. Some 92.2% of patients were suffering from at least one chronic disease, and there was a significant statistical difference between the mean points of all aspects of quality of life of those suffering from chronic diseases and those without a history of chronic diseases(P<0.001). Moreover, there was a significant relationship between the quality of life on the one hand and gender, marital status, economic status, and education on the other(P<0.05). Conclusion: The findings show that an increase in the number of chronic diseases leads to a decrease in the quality of life, and that the application of appropriate educational and interventional approaches can help take effective steps to enhance the old people's health.

Evaluation of the Serum Melatonin Levels in the Treatment of Patients with Multiple Sclerosis

Arak Medical University Journal, 2018

Background: Multiple sclerosis (MS) is a myelinating inflammation and an impairment of neuronal cell regeneration in the central nervous system with unknown causes. The aim of this study was to evaluate serum melatonin levels in the treatment of patients with multiple sclerosis. Materials and Methods: A prospective study and a Cohort were conducted on 40 MS patients with multiple sclerosis patients referring to instituate MS in Arak city for one year. In this study, patients who were treated with interferon-moderating drugs and who had not been treated for more than one year were randomly selected. A questionnaire containing demographic information and clinical information and separation of interacting factors was completed and completed. Clinical information included MRI, VEP, EDSS (Expanded Disability Status Scale) score, and clinical symptoms. The patients also received peripheral blood samplers 3 times in 6 months intervals to measure melatonin and their melatonin levels, and th...

The Prevalence of Various Phenotypes of Polycystic Ovary Syndrome: A Community-Based Study in Southwest of Iran

Introduction: There is very little information about the prevalence of polycystic ovary syndrome at the community level; heterogeneity in diagnostic criteria and lack of universal agreement on the definition of each criterion for population based studies complicate comparability of existing literature. This study aimed to assess the prevalence of different phenotypes of polycystic ovary syndrome in a large community-based study conducted in the southwest of Iran. Materials and Methods: A total of 646 reproductive-aged women were randomly selected using the stratified, multistage probability cluster sampling method. The prevalence of polycystic ovary syndrome according to the Rotterdam criteria and its various phenotypes were estimated using universal assessment of ultrasonographic parameters, hormonal profiles and clinical histories. Results: The estimated prevalence of polycystic ovary syndrome in this population based study using the Rotterdam criteria was 14.1(n=85). There were 279 (46.3%) women who had no symptoms of polycystic ovary syndrome and were completely normal. Among women with polycystic ovary syndrome, phenotypes A, B, C and D were observed in 11, 19, 42 and 13 women, respectively. Conclusions: The most common symptoms observed in this study in order of frequency were hyperandrogenism, polycystic ovary on sonography and menstrual disorders, indicating the need for more studies on the priority of paraclinical assessment, based on universal agreement on definitions for the diagnosis of polycystic ovary syndrome.

Social and Cultural Dimensions of Genetic Blood Diseases An Anthropological study in the Omani Society

Journal of Arts and Social Sciences [JASS], 2016

This study attempts to monitor the most important impacts of social and cultural variables on the health situation in the Omani society in general, and the incidence of hereditary blood disease in particular. The study aims to identify the social and cultural dimensions of health and disease in terms of concept and theoretical perspectives; the most important health indicators; the magnitude and spread of hereditary blood diseases in the Sultanate of Oman; and the disclosure of some of the social and cultural factors, and the difficulties facing the health pattern. The study relied on some Theoretical frameworks that provided scientific explanations about addressing the social and cultural dimensions of health and disease. Methodologically, the study was based on both quantitative and qualitative techniques. The study concluded that there are many social and cultural dimensions that shaped some of the factors that caused the incidence of hereditary blood disease in the Omani society...

Construction and Standardization of a Questionnaire Investigating Cultural Reasons Causing Concurrent Obsession and Major Depressive Disorders in Iran

Journal of Mazandaran University of Medical Sciences, 2015

Background and purpose: Cultural signs may be found among people that speak a local dialect or live in a specific region or historical period. These cultural signs could influence psychopathology. The aim of this study was to design and validate a questionnaire that could evaluate the cultural factors causing concurrent obsessions and major depressive disorders in Iran. Materials and methods: To design the questionnaire, 10 psychologists and psychiatrists who were members of academic boards were questioned by an open questionnaire. Then, the answers to the questions were classified and based on exploratory factor analysis the questionnaire containing 11 factors and 79 questions was confirmed. Internal homogeneity was analyzed by Cronbach's alpha. Results: The results of Cronbach's alpha for all factors showed that the highest reliability was 0.90 and the lowest was 0.42. In exploratory factor analysis using Varimax rotation 11 factors were extracted that predict 47.3% of the scale variance. 25 factors were extracted of which14 had less than three items, therefore they were omitted because of not being able to acquire reliability as sub factors. Accordingly, a questionnaire containing 11 factors and 79 questions was constructed. Conclusion: The findings showed that the instrument could identify the cultural factors that cause concurrent obsession and major depressive disorders in Iran.

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