Orthotopic Liver Transplantation Followed By Double Cord Blood Transplantation In A Patient With Erythropoietic Protoporphyria (original) (raw)

A 4-year-old female with erythropoietic protoporphyria underwent orthotopic liver transplantation followed by double cord blood transplantation due to end-stage liver failure with jaundice, portal hypertension, and hypoalbuminemia. Despite complications such as cholangitis and gut graft-versus-host disease, successful engraftment occurred with significant reduction in zinc protoporphyrin levels and restoration of hepatic function post-transplant. This case represents the first pediatric instance of sequential liver and double cord blood transplantation for this condition.