Socio-demographic Factors Affecting Health-related-quality of Life in Post-renal-transplant Patients (original) (raw)
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Quality of Life Research, 2009
Introduction Kidney transplantation improves the quality of life of end-stage renal disease patients. The quality of life benefits, however, pertain to patients on average, not to all transplant recipients. The aim of this study was to identify factors associated with health-related quality of life after kidney transplantation. Methods Population-based study with a cross-sectional design was carried out and quality of life was assessed by SF-36 Health Survey Version 1. A multivariate linear regression model was constructed with sociodemographic, clinical and laboratory data as independent variables. Results Two hundred and seventy-two kidney recipients with a functioning graft were analyzed. Hypertension, diabetes, higher serum creatinine and lower hematocrit were independently and significantly associated with lower scores for the SF-36 oblique physical component summary (PCSc). The final regression model explained 11% of the PCSc variance. The scores of oblique mental component summary (MCSc) were worse for females, patients with a lower income, unemployed and patients with a higher serum creatinine. The regression model explained 9% of the MCSc variance. Conclusions Among the studied variables, comorbidity and graft function were the main factors associated with the PCSc, and sociodemographic variables and graft function were the main determinants of MCSc. Despite comprehensive, the final regression models explained only a little part of the heath-related quality of life variance. Additional factors, such as personal, environmental and clinical ones might influence quality of life perceived by the patients after kidney transplantation.
Demographic Correlates of Perceived Health Status after Renal Transplantation
Khyber Medical University Journal, 2016
OBJECTIVES: to identify the demographic factors that can make recipients vulnerable to develop poorer perceptions of health despite ahealthy graft functioning and to evaluate recipients’ perceived healthstatus (PHS) influences their coping and adjustment with the alteredlife styles and challenges after transplant.METHODS: In this longitudinal study, PHS was measured by a self-developed questionnaire that reflected the symptoms’ severity and frequency measured by the common immunosuppressant side effects. Actual physical health status was measured by the clinical data that comprised of kidney function tests (serum creatinine, blood urea nitrogen, uric acid) and general health indicators such as blood pressure, cholesterol and haemoglobin levels.RESULTS: There was significant correlation among sociodemographicfactors and perceptions of health status after a successful renal transplant over time. Age had a significant negative association with PHS, indicating that older recipients tend...
Iranian journal of kidney diseases, 2009
The impact of socioeconomic status on the chance of being a candidate of kidney transplantation and its effect on graft survival has been documented. Our aim was to investigate the association of socioeconomic status with kidney allograft recipients' health-related quality of life and level of anxiety and depression. Two hundred and forty-two kidney transplant recipients were categorized according to their monthly family income into low-income, moderate-income, and high-income groups. These groups were compared in terms of health-related quality of life (short form-36) and level of anxiety and depression symptoms (hospital anxiety depression scale). There was a trend of higher HRQOL scores in association with a higher income, which was significant for the total HRQOL score and its subdomains of physical function and role limitation due to physical and emotional problems. A slight increase in anxiety symptom scores was also seen in kidney recipients with lower incomes; however, t...
Racial and Gender Differences in Quality of Life Following Kidney Transplantation
Image--the journal of nursing scholarship
To determine if race or gender affected changes in quality of life (QoL) reported by nondiabetic kidney transplant recipients from pre- to 6 and 12 months post-transplant and offer possible explanations. Information gained may offer direction for interventions designed to enhance post-transplant QoL for patients who may be less likely to attain improved outcomes. Descriptive, prospective clinical study. A convenience sample of 90 male and female Caucasian-American and African-American patients was used. Patients were 19 to 67 years of age, nondiabetic, and undergoing kidney transplantation at one university hospital located in the southern United States. Data were collected 1990 to 1995. Three questionnaires measuring QoL were used: the Sickness Impact Profile, Ferrans and Powers' Quality of Life Index, and the Adult Self-Image Scales. Patients completed questionnaires at the time of transplant and at their routine 6- and 12-month post-transplant evaluation visits. Repeated measures analysis of variance with multiple pre-planned comparisons of least-squares (LS) means were performed to determine if differences existed between and within study groups over time. African-Americans achieved less improvement than Caucasian-Americans in affective as well as functional measures of QoL. Women scored consistently lower than men on most QoL measures at baseline and reported greater improvement in functional ability while perceptions of self-image remained low. Although transplantation dramatically improves QoL, some segments of the patient population, namely African-Americans and women, do not benefit to the same extent as others. Nurses need to recognize sociocultural differences in patients and how these differences affect care requirements.
Health-Related Quality of Life and Clinical Outcomes in Kidney Transplant Recipients
American Journal of Kidney Diseases, 2011
Background: Health-related quality of life (HRQoL) is an important outcome measure in patients with chronic kidney disease. It also has been shown repeatedly to predict mortality in various patient populations. In a prospective cohort study, we assessed the association between HRQoL and long-term clinical outcome in kidney transplant recipients. Study Design: Prospective prevalent cohort study. Setting & Participants: We collected sociodemographic parameters, medical and transplant history, and laboratory data at baseline from 879 prevalent kidney transplant recipients (mean age, 49 Ϯ 13 [standard deviation] years; 58% men; and 17% with diabetes mellitus). Predictor: We assessed HRQoL using the KDQoL-SF (Kidney Disease Quality of Life Short Form) questionnaire and assessed depressive symptoms using the Center for Epidemiologic Studies-Depression Scale. Outcomes: All-cause mortality and death-censored transplant loss or death with functioning transplant. Cox regression models and semiparametric competing-risks regression analyses were used to measure associations between HRQoL scores and outcomes. Results: Most examined HRQoL domains were associated with clinical outcome in unadjusted models. After adjusting for several important confounders, the 36-Item Short Form Health Survey (SF-36) Physical Composite Score and Physical Functioning and General Health Perception subscale scores remained independently associated with clinical outcomes. Every 10-point increase in SF-36 Physical Composite Score and Physical Functioning and General Health Perception scores was associated with 18% (HR, 0.82; 95% CI, 0.71-0.95), 11% (HR, 0.89; 95% CI, 0.84-0.94), and 7% lower risks of mortality (HR, 0.93; 95% CI, 0.88-1.00), respectively. Limitations: Single-center study. Conclusions: We showed that the SF-36 Physical Composite Score and Physical Functioning and General Health Perception KDQoL-SF domain scores are associated independently with increased risk of mortality in kidney transplant patients. Regular assessment of HRQoL may be a useful tool to inform health care providers about the prognosis of kidney transplant recipients. Additional studies are needed to assess whether interventions aimed at improving HRQoL would improve clinical outcomes in this patient population.
Nephrology Dialysis Transplantation
Background Health-related quality of life (HRQOL) is an increasingly important patient-reported outcome in kidney transplant recipients (KTRs). This study explored relationships between symptom prevalence and burden with HRQOL, and age and gender differences in symptom experience. Methods Eligible Dutch KTRs transplanted in Leiden University Medical Center were invited for this cross-sectional study. HRQOL, and occurrence and burden of 62 symptoms were measured using validated questionnaires. Univariate and multivariate regression analysis were used for investigating the associations of symptom experience with mental and physical HRQOL, and differences in symptom experience between genders and KTRs of diverse age groups. Results A total of 631 KTRs were analyzed; the mean (standard deviation) age was 61.3 (11.3) years, and 62% were male. The median (interquartile range) number of symptoms was 14 (7–22), with a burden of 20 (8–37; range 0–244). Per extra symptom, physical and mental ...
Health related quality of life in renal transplantation: 2 years of longitudinal follow-up
Medicina Clínica (english Edition), 2017
Background and objective: Health related quality of life (HRQoL) is recognised as an outcome measure in kidney transplantation. In this study was assessed changes on HRQoL and kidney-specific symptoms, also was evaluated the effect of socio-demographic and clinical parameters on patient's perceived HRQoL. Patients and method: A longitudinal study was done, at 5 time-points over 2 years after transplantation. To evaluate HRQoL the Kidney Disease Quality of Life Questionnaire Short Form was administrated, and Hospital Anxiety and Depression Scale was used to assess psychological distress. Results: At 6 months after transplantation, patients had similar HRQoL scores compared to the general population. The improvement on effects of kidney disease domain could be considered as large (Á 2 = 0.29), and medium on burden of kidney disease domain (Á 2 = 0.12), work status domain (Á 2 = 0.12), and sexual function domain (Á 2 = 0.13). Psychological distress, depressive symptoms, haemoglobin, and serum creatinine had significant influence on patient's perceived HRQoL over 2 years after transplantation. Conclusions: An improvement of HRQoL was observed on general and specific-targeted symptoms over 2 years after renal transplantation.
Quality of life and its related factors in kidney transplant recipients
2019
Patients undergoing transplantation, experience significant changes in their quality of life. The aim of this study was to determine the quality of life and related factors in kidney transplant recipients. This descriptive-analytic cross-sectional study was performed on 136 kidney transplant recipients referring to nephrology clinic of Imam Khomeini Hospital in Ardabil through convenience sampling method in 2016. Data was collected by using a demographic form, Short Form Health Survey (SF36), physical stress index, Kidney Transplantation Self-Management Scale, Kidney Transplantation Self-Care Self-Efficacy Scale and Beck's Depression Inventory. Data were analyzed by SPSS software version 16 using descriptive and analytical methods. The mean score of physical health (55.01 ±19.48) was slightly higher than the mental health (42.86 ± 20.91). Self-efficacy (β = 0.29), depression symptoms (β = -0.34), age (β = -0.36) and gender (β = 0.15) were as predictors of the physical health com...
Exploring quality of life among renal and liver transplant recipients
Annals of Saudi medicine
Despite the worldwide recognition of the importance of quality of life (QOL) assessment, research data on QOL for renal and liver transplant recipients are limited. The main objective of this study was to explore and compare QOL in renal and liver transplant patients. This cross-sectional study was conducted at at King Abdulaziz Medical City, Saudi Arabia. Saudis 16 years of age or more who received liver or renal transplantation at least three months before the study participated. QOL was evaluated using the World Health Organization QOL instrument (WHOQOL-BREF). Renal and liver transplant patients were highly or moderately satisfied with most circumstances of life. Using data for subjects in all WHO centers, renal and liver transplant patients domain scores in this study were significantly higher in the psychological health domain, social relations and environmental domain (P < .0001). The results also show that renal and liver transplant recipients who were male, or had higher...
Predictors of Perceived Health Status in Patients after Kidney Transplantation
Transplantation, 2006
Background. Patients after kidney transplantation have decreased mortality, morbidity and better quality of life compared to people on dialysis. Major efforts are being directed towards research into graft and patient survival. Research into quality of life is less intensive. The aim of this study was to explore the predictors of perceived health status (PHS) in kidney transplant recipients. Methods. Out of 218 patients after kidney transplantation 138 participated in the study. Linear regression analysis was performed to predict PHS, measured with the SF-36 questionnaire, in three age categories (Ͻ40, 40 -59, Ն60 years). Independent variables included social support (measured with the Social Support List Discrepancies questionnaire), sociodemographic and medical variables, side effects and compliance. Results. Predictors of better PHS in patients Ͻ40 years were better social support (PՅ0.001), lower creatinine (PՅ0.001) and lower stress from adverse effects (PՅ0.001). In the group of patients aged 40 -59 years higher education (PՅ0.05), increased housekeeping activities (PՅ0.01) and lower stress from adverse effects (PՅ0.001) predicted better PHS. In the last age group predictors of better PHS were lower rate of dialysis (PՅ0.05) and posttransplant hospitalizations (PՅ0.01), absence of diabetes mellitus (PՅ0.01) and lower stress from adverse effects (PՅ0.05). Conclusions. Major differences exist in PHS among kidney transplant recipients depending on their age. Side effects of therapy are the most important predictor of PHS for all age groups. PHS of young patients mostly depends on their renal function and their social support. Education and working activities are most important for middle-aged people whereas in older patients PHS is mostly affected by comorbidity.