Tracking the NMB level via a switching system mass control strategy (original) (raw)

NMB target level tracking via an optimization based control law

IFAC-PapersOnLine, 2015

In this paper a state-feedback law for the control of the neuromuscular blockade level is presented. The control law is designed based on an optimal problem that is relaxed into a semidefinite program using a change of variable. For that purpose a parsimoniously parameterized model is used to describe the patient's response to a muscle relaxant. Due to clinical restrictions the controller action begins when the patient recovers after an initial drug bolus. The results obtained encourage the implementation of this controller in the clinical environment even in the presence of noise.

Weigand_et_al-2016-Rapid_Communications_in_Mass_Spectrometry.pdf

The denitrifier method allows for highly sensitive measurement of the 15 N/ 14 N (δ 15 N value) and 18 O/ 16 O (δ 18 O value) of nitrate dissolved in natural waters and for highly sensitive δ 15 N measurement of other N forms (e.g., organic N) that can be converted into nitrate. Here, updates to instrumentation and protocols are described, and improvements in data quality are demonstrated. METHODS: A 'heart cut' of the N 2 O was implemented in the extraction system to (1) minimize introduction of contaminants into the mass spectrometer, reducing isotopic drift and decrease the fraction of sample lost at the open split to improve sensitivity. Referencing protocols were updated, including a correction scheme for a weak dependence of nitrate δ 18 O values on nitrate concentration. Analyses of samples from the US GEOTRACES North Atlantic Program and of reference solutions from the same analysis batches were used to characterize performance. RESULTS: The drift is typically <0.1‰ for both δ 15 N and δ 18 O values. Within-batch and inter-batch replication yields 1 standard deviation (SD) of ≤0.06‰ for δ 15 N values and ≤0.14‰ for δ 18 O values down to 5 μM nitrate and ≤0.08‰ and ≤0.23‰ at 2 and 1 μM. The blank is typically 0.06 nmol N, 0.3% of the N in a 20 nmol N sample. Differences between reference materials in seawater are indistinguishable from reported differences for δ 15 N values, with a contraction for δ 18 O values of ≤5%. CONCLUSIONS: The new instrumentation and protocols yield nitrate isotopic data with external precision of ≤0.1‰ for large sample sets such as those derived from oceanographic sections. Further study should investigate the causes of (1) the weak dependence of nitrate δ 18 O values on nitrate concentration and (2) the inter-batch variation in the δ 18 O contraction (due mostly to oxygen atom exchange with water). Nevertheless, comprehensive correction schemes are in place for the measurement of both the δ 15 N and δ 18 O values of nitrate.

Automation of MCDOR at NMT-3 Los Alamos National Laboratory. Final report

1997

This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, make any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not necessan'ly constitute or imply its endorsement, recommendation, or favoring by the United States Government or any agency thereof. The views and opinions of authors expressed herein do not necessarily state or reflect those of the United States Government or any agency thereof.. DISCLAIMER Portions of this document may be illegible in electronic image products. Images are produced from the best available original document. I I ' n , 2 The automation of various parts of multiple-cycle direct oxide reduction (MCDOR) at LANL's NMT-3 was the goal of this research and development activities. In particular, originally the following goals were assigned to the author by the NMT-3 technical staff leaders (Greg Bird, Jim McNeese, Joel Williams) : 1-Design and fabricate an automation set up. accuracy of (gm) may be reprogrammable for specific weight set points. Thus, when a set point in weight is reached or by means of a vibratory feeder feeding a multiple-pan container (Inverted Bicycle Seat, IBS), on the electronic balance, the electronic balance w i l l send an electronic signal out to switch off the vibratory feeder. 2-Research, development, conceptualization, design and fabrication of an automation set up to automatically transport the mixture of powders in part 1 to a feeding location (station) where they w i l l be added to the molten solvent inside the furnace. 3-Integration of systems in 1 and 2 above. 4-Research, development, conceptualization, design and fabrication of a levitation (suspension) system for the automatic weighing station in part 1. The above goals were all achieved during the research and development period and the completed system and the associated hardware and software were delivered to LANL-NMT3 by April 1993. Additional research and development work is recommend to further automatic and integrate the developed system with the MCDOR furnace system. DataPac-M Keypad which allows diflerent inputs to the computer via a bidirectional data interface GoldPac-M Applications tor jewelry (three units that can be called up, automatic reconciliation of weight values with inputled prices) LabP ac-M Applications for the lab (differential weighing, % formula, net total) PharmaPac-M Applications for pharmaceutical products (piece counting, statistis, net total) Prof ac-M Applications for production (piece counting. statistics. kcontrol) Stat Pac-M For the statistical filling process control according to different tolerance systems and pharmacopy XPac-M Allows realization of customer-specific applications 22

Scientific Progress of the Mc-Pad Network

MC-PAD is a multi-site Initial Training Network on particle detectors in physics experiments. It comprises nine academic participants, three industrial partners and two associated academic partners. 17 recruited Early Stage and 5 Experienced Researchers have performed their scientific work in the network.

The Second EWGRD Round Robin: Inter-Comparison of93mNb Measurements

EPJ Web of Conferences

Following on from an initial Round Robin inter-comparison of gamma spectrometry measurements reported in 2014, this paper presents the results of the second part of a further Round Robin inter-comparison commissioned in 2018 by the European Working Group on Reactor Dosimetry. The purpose of the exercise was to demonstrate the level of consistency between different organisations’ measurements of the93Nb(n,n’)93mNb reaction, which plays a key role in underwriting reactor dosimetry assessments. To achieve this, measurements of93mNb activity were performed by twelve European organisations on six sets of near identical niobium samples, each having its own geometry and tantalum concentration. The samples were provided by CEA, France and irradiated in the MARIA reactor, operated by National Centre for Nuclear Research, Poland. Participants provided their results to an independent referee who collated and compared the data. The inter-comparison has demonstrated agreement to within standard ...

Automation and control in high power pulsed NMR

Journal of Physics E Scientific Instruments

The article reviews developments in control and automation of conventional high power pulsed NMR spectrometers. A short introduction to the physical background and the methods is given. Automation and control of the various components of a pulsed YMR spectrometer are then illustrated and problems are discussed. Following this, concepts of spectrometer system automation are treated, using examples of home made, as well as commercial equipment. Another section is devoted to the automation of a pulsed NMR lab comprising several m m spectrometers. Finally the application of pulsed NMR spectroscopy in industrial processing is discussed. Jeener J and Broekaert P 1967 Phys. Rev. 157 232 Jeener J and Segebarth C 1975 Rev. Sci. Instrum. 46 1478-80 Kan S, Gonord P, Fan M, Sauzade M and Courtien J 1978 Rev. Sci. Instrum. 49 785-9 Karlicek R F and Lowe I J 1978

NMR+Logging+Principles+and+Applications

As the largest oilfield service company in the world, Halliburton is committed to providing services of the highest quality and best value, not only through field delivery but also through an understanding of underlying technology. This book is an example of this commitment, and I trust that you will find it useful in learning how NMR services can be of benefit in your applications.