Do older people with poor sleep quality have worse cardiac autonomic control? (original) (raw)
Related papers
International Journal of Research in Medical Sciences
Background: Poor sleep quality adversely affects the person’s homeostasis via combination of impairments to multiple physiological-mechanisms. Autonomic functions are important for different aspects of health and disease. Objective of study was to analyze the impact of subjective sleep quality on autonomic functions in different age groups of adults.Methods: A total of 375 apparently healthy adults from community were randomly selected for this cross-sectional observational study. They were divided into three groups based on the age distributions: Group 1: 18-30 years (n = 146); Group 2: 31-45 years (n = 112); and Group 3: 46-60 years (n = 117). Following assessments were done in all the participants in three groups: Anthropometric measurements, Pittsburgh Sleep-quality Index (PSQI), Electrocardiography (ECG), Autonomic functions based on frequency domain heart rate variability (HRV). Two-way analysis of variance followed by post hoc analysis was done for intergroup comparisons of ...
Age-related losses in cardiac autonomic activity during a daytime nap
In healthy, young individuals, a reduction in cardiovascular output and a shift from sympathetic to parasympathetic (vagal) dominance is observed from wake into stages of nocturnal and daytime sleep. This cardiac autonomic profile, measured by heart rate variability (HRV), has been associated with significant benefits for cardiovascular health. Aging is associated with decreased nighttime sleep quality and lower parasympathetic activity during both sleep and resting. However, it is not known whether age-related dampening of HRV extends to daytime sleep, diminishing the cardiovascular benefits of naps in the elderly. Here, we investigated this question by comparing the autonomic activity profile between young and older healthy adults during a daytime nap and a similar period of wakefulness (quiet wake; QW). For each condition, from the electrocardiogram (ECG), we obtained beat-to-beat HRV intervals (RR), root mean square of successive differences between adjacent heart-beat-intervals...
Measuring quality of sleep and autonomic nervous function in healthy Japanese women
Neuropsychiatric Disease and Treatment, 2014
The purpose of this study was to determine the relationship between quality of sleep and autonomic nervous functioning in healthy adult Japanese women using three measures, namely, the Pittsburgh Sleep Quality Index (PSQI) for subjective assessment of sleep quality, actigraphy for objective assessment of sleep, and heart rate variability using high frequency and low frequency domains. Participants were 31 healthy women in their 20s to 40s who met the selection criteria, including having normal monthly menstrual periods. Participants were categorized as good or poor sleepers according to their PSQI score. Median correlation coefficients of activity count and high frequency were −0.62 (range −0.43 to −0.84) for good sleepers and −0.45 (range 0.003 to −0.64) for poor sleepers. Good sleepers showed a significantly higher correlation of activity count and high frequency (Z=−2.11, P,0.05). Median correlation coefficients of activity count and low frequency/high frequency were 0.54 (range 0.29-0.73) for good sleepers and 0.41 (range 0.11-0.63) for poor sleepers. The PSQI, actigraphy data, and heart rate variability results showed positive correlations between sleep time as measured by PSQI and duration of inactivity as measured by actigraphy (r=0.446, P,0.05) and sleep time as measured by actigraphy (r=0.377, P,0.05), and a negative correlation between sleep time as measured by PSQI and the correlation coefficients of activity count and high frequency (r=−0.460, P,0.01). These results support the finding that sleep-wake rhythms can be monitored efficiently with actigraphy, providing accurate data that can support the diagnosis of sleeping disorders. Furthermore, actigraphy data were associated with heart rate variability and PSQI findings, but only in subjects who were poor sleepers. Actigraphy is an accurate, efficient, rapid, and inexpensive test for determining objective and subjective sleeping problems, and can also be used in clinical tests for sleep assessment.
The Association of Sleep Duration and Quality with Heart Rate Variability and Blood Pressure
PubMed, 2020
Background: The current study was conducted to evaluate the relation of sleep duration and quality with blood pressure (BP) and heart rate variability (HRV). Materials and methods: This cross-sectional study was carried out in 2017 among 260 staff of a university hospital in Isfahan, Iran. They were selected by multi-stage random method from different wards. Time domain spectral analysis was used to measure a number of HRV parameters. The long-term components of the HRV were estimated using the standard deviation of the normal-to-normal interval (SDNN). The square root of the mean squared differences of successive NN intervals (RMSSD) was calculated by statistical time domain measurements; SNN50, and PNN50 were measured. Pittsburg sleep quality index (PSQI) questionnaire was used to assess sleep quality. Results: Higher PSQI score correlated with lower SDANN rise (OR=0.92). Fairly bad to very good subjective sleep quality had association with lower SDANN (OR=0.43). Very high sleep latency to very low sleep latency ratio had association with lower SDANN (OR=0.39) and lower PNN50 (OR= 0.44). Sleep duration and HRV parameters had no significant association. Fairly bad sleep efficiency to very good sleep efficiency ratio was correlated with lower SDANN (OR= 0.29). Very high daytime dysfunction to very low daytime dysfunction ratio had correlation with lower SDANN (OR=0.35). Very bad compared to very good subjective sleep quality had significant correlation with higher Heart rate (HR) (B=0.03). Very high sleep latency compared to no sleep latency was associated with higher HR (B=4.74). Very high compared to very low amount of sleep disturbances correlated with higher SBP levels (B=15.2). Using sleep medication less than once a week compared with no history of taking such drugs was associated with higher HR (B=16.4). Conclusion: Our findings showed that poor sleep quality are adversely associated with HRV, HR and BP. This finding should be considered in clinical and preventive recommendations.
High Cardiac Vagal Control is Related to Better Subjective and Objective Sleep Quality
Biological Psychology
Cardiac vagal control (CVC) has been linked to both physical and mental health. One critical aspect of health, that has not received much attention, is sleep. We hypothesized that adults with higher CVC - operationalized by high-frequency heart rate variability (HF-HRV) - will exhibit better sleep quality assessed both subjectively (i.e., with Pittsburgh Sleep Quality Index) and objectively (i.e., with polysomnography). HF-HRV was measured in 29 healthy young women during an extended neutral film clip. Participants then underwent full polysomnography to obtain objective measures of sleep quality and HF-HRV during a night of sleep. As expected, higher resting HF-HRV was associated with higher subjective and objective sleep quality (i.e., shorter sleep latency and fewer arousals). HF-HRV during sleep (overall or separated by sleep phases) showed less consistent relationships with sleep quality. These findings indicate that high waking CVC may be a key predictor of healthy sleep. Copyr...
Heart rate variablity during daytime naps in healthy adults.pdf
In healthy individuals, a reduction in cardiovascular output and a shift to parasympathetic/vagal dominant activity is observed across nocturnal sleep. This cardiac autonomic profile, often measured by heart rate variability (HRV), has been associated with significant benefits for the cardiovascular system. However, little is known about the autonomic profile during daytime sleep. Here, we investigated the autonomic profile and short-term reliability of HRV during daytime naps in 66 healthy young adults. Participants took an 80–120 min polysomnographically recorded nap at 1:30pm. Beat-by-beat RR interval values (RR), high (HF) and low frequency (LF) power, total power (TP), HF normalized units (HFnu), and the LF/HF ratio were obtained for 5 min during presleep wakefulness and during nap sleep stages (N2, N3, REM). A subsample of 37 participants took two additional naps with 2 weeks between recordings. We observed lengthening of the RR, higher HF and HFnu, and lower LF/HF during NREM, compared with REM and wake, and a marked reduction of LF and TP during N3. Intraclass correlation coefficients highlighted a short-term stability of RR and HF ranging across sleep stages between 0.52–0.76 and 0.52–0.80, respectively. Our results suggest that daytime napping in healthy young adults is associated with dynamic changes in the autonomic profile, similar to those seen during nocturnal sleep. Moreover, a reliable intraindividual measure of autonomic cardiac activity can be obtained by just a single daytime nap depending on specific parameters and recording purposes. Nap methodology may be a new and promising tool to explore sleep-dependent, autonomic fluctuations in healthy and at-risk populations.
Heart Rate and Heart Rate Variability Modification in Chronic Insomnia Patients
Behavioral Sleep Medicine, 2013
Chronic insomnia is highly prevalent in the general population, provoking personal distress and increased risk for psychiatric and medical disorders. Autonomic hyper-arousal could be a pathogenic mechanism of chronic primary insomnia. The aim of this study was to investigate autonomic activity in patients with chronic primary insomnia by means of heart rate variability (HRV) analysis. Eighty-five consecutive patients affected by chronic primary insomnia were enrolled (38 men and 47 women; mean age: 53.2˙13.6). Patients were compared with a control group composed of 55 healthy participants matched for age and gender (23 men and 32 women; mean age: 54.2˙13.9). Patients underwent an insomnia study protocol that included subjective sleep evaluation, psychometric measures, and home-based polysomnography with evaluation of HRV in wake before sleep, in all sleep stages, and in wake after final awakening. Patients showed modifications of heart rate Correspondence should be addressed to Benedetto Farina,
Autonomic cardiac activity in adults with short and long sleep onset latency
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2018
Autonomic cardiac activity during sleep has been widely studied. Research has mostly focused on cardiac activity between different sleep stages and wakefulness as well as between normal and pathological sleep. This work investigates autonomic activity changes during sleep onset in healthy subjects with long and short sleep onset latency (SOL). Polysomnography (PSG) and electrocardiography (ECG) were simultaneously recorded in 186 healthy subjects during a single night. Autonomic activity was assessed based on frequency domain analysis of RR intervals and results show that the analysis of RR intervals differs significantly between the short SOL and the long SOL groups. We found that the spectral power in the low frequency band (LF) was significantly higher in the long SOL group compared to the short SOL group in the first 10 minutes in bed intended to sleep. There was no significant difference for LF and the spectral power in the high frequency band (HF) 10 minutes before and after s...
Effects of Aging and Cardiac Denervation on Heart Rate Variability During Sleep
Circulation, 2001
Background-Cardiac vagal predominance increases the RR interval and RR high-frequency (HF) variability during non-rapid eye movement (non-REM) sleep (stages I through IV) in young subjects. Aging suppresses deep sleep, but effects of age-related changes in sleep architecture on RR are unknown. Whether mechanical effects of changes in the breathing pattern on the sinus node during sleep affect RR variability is unclear.