Plant Sterol-Enriched Low Fat Flavoured Milk Enhances The Attainment of LDL-Cholesterol Goal In Hypercholesterolemic Subjects (original) (raw)

The study was conducted to investigate the effect of phytosterols (PS) enriched flavoured milk on total and LDL (Low density lipoprotein)-cholesterol levels in subjects with hypercholesterolemia. Phytosterol is added at 3 different levels of concentration to enrich the low fat flavoured milk samples. The prepared samples were T1 (2 % PS), T2 (2.5 % PS), T3 (3 % PS) and control samples were also prepared and standardized. The developed products were analyzed at regular intervals for their physico chemical, nutritional, organoleptic properties and microbial count for the period of 1 month. The results were shown that the flavoured milk sample T1 (combination of toned milk, cocoa, sugar, stabilizer (500:4: 35:0.2) enriched with 2 % PS was more acceptable in terms of its sensory attributes. To evaluate the efficacy of phytosterol enriched flavoured milk (T1), twelve hypercholesterolemic human subjects were selected with cholesterol range of 192.0-221.8 mg/dl in the age group of 25-45 years. The selected subjects were received one 100 ml serving of either plain (control) low-fat or phytosterol enriched (2.0 g of free sterol equivalents) drinkable flavoured milk per day along with the main meal for 30 days. Enrichment of phytosterol in low fat flavoured milk to the experimental group, brought a significant (p < 0.05) reduction of total cholesterol(2.53 %) and LDLcholesterol levels(2.62 %).Triglycerides and HDLcholesterol reduced by 1.10 per cent and 1.22 per cent respectively but were not significant at 5 per cent level (p > 0.05). In the control group an insignificant increase in total cholesterol, LDLcholesterol and decrease in HDLcholesterol and decrease in triglycerides level were observed. The use of phytosterols as supplement can lower the total and LDL cholesterol levels, thereby reducing the risk of cardiovascular disease (CVD).

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