Neutrophils cause critical illness in COVID-19 and reveal CDK6 inhibitors as potential treatment (original) (raw)

High neutrophils and triglycerides lead to critical illness in COVID-19 and reveal CDK6 inhibitors as potential treatment

Justin Cope

2022

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Patients with COVID-19: in the dark-NETs of neutrophils

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A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients

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Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulin

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Heterogeneity of neutrophils and inflammatory responses in patients with COVID-19 and healthy controls

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Critically ill COVID-19 status associated trait genetics reveals CDK6 inhibitors as potential treatment

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The Emerging Role of Neutrophils in the Pathogenesis of Thrombosis in COVID-19

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Neutrophilia during hospitalization predicts ARDS and risk of death in COVID-19 patients

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Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

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Calming the inflammatory storm in severe COVID-19 infections: Role of biologics- A narrative review

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Decreased neutrophil phagocytosis and killing of bacteria in COVID-19 patients

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IL-6 Inhibitors in the Treatment of Serious COVID-19: A Promising Therapy?

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Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19

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CD177, a specific marker of neutrophil activation, is a hallmark of COVID-19 severity and death

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Interleukin-6 and Neutrophil–Lymphocyte Ratio in Predicting Outcome of Confirmed COVID-19 Patients

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A neutrophil activation signature predicts critical illness and mortality in COVID-19

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Is IL 6 Evaluation And It’s Inhibitors Are Really Promising Therapy In The Treatment of COVID-19: A Removal Of Myths And Facing The Real Mirror Image

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Immunotherapies for COVID-19: lessons learned from sepsis

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Neutrophil and monocyte dysfunctional effector response towards bacterial challenge in critically-ill COVID-19 patients

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Influence of IL-6 levels on patient survival in COVID-19

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Blood Neutrophils from Children with COVID-19 Exhibit Both Inflammatory and Anti-Inflammatory Markers

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An inflammatory cytokine signature predicts COVID-19 severity and survival

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Influence of SARS-COV-2 Infection on Cytokine Production by Mitogen-Stimulated Peripheral Blood Mononuclear Cells and Neutrophils in COVID-19 Intensive Care Unit Patients

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Monocyte-Driven Atypical Cytokine Storm and Aberrant Neutrophil Activation as Key Mediators of COVID19 Disease Severity

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Inflammation Associated with Disease Severity and Fatality of COVID-19

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Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early prognostic marker for severe COVID-19

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2020

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