Motor performance of children during treatment for acute lymphoblastic leukemia (original) (raw)

Motor problems in children undergoing treatment for acute lymphoblastic leukemia (ALL) persist and manifest differently over time, with gross motor issues arising during treatment and fine motor skills declining post-treatment. This study utilized the Movement Assessment Battery for Children to assess daily-life motor skills in children under treatment, revealing significant impairments related to vincristine and potentially methotrexate neurotoxicity. Findings highlight the importance of monitoring both gross and fine motor skills throughout ALL treatment, suggesting distinct neurotoxic mechanisms may underlie the observed deficits.