Chloroperoxidase-catalyzed halogenation of antipyrine, a drug substrate of liver microsomal cytochrome P-450 (original) (raw)

NADPH and H2O2-dependent reactions of cytochromeP-450LMcompared with peroxidase catalysis

Reinhard Renneberg

FEBS Letters, 1978

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Oxidative N-demethylation of N,N-dimethylaniline by purified isozymes of cytochrome P-450

Dr. Ramendra Pati Pandey

Biochemical Pharmacology, 1989

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Differences in the mechanism of NADPH- and cumene hydroperoxide-supported reactions of cytochrome P-450

Jorge Capdevila

Archives of Biochemistry and Biophysics, 1980

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The mechanism of action of cytochrome P-450. Occurrence of the 'NIH shift' during hydroperoxide-dependent aromatic hydroxylations

Harold Seifried

European journal of biochemistry / FEBS, 1978

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Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes

David Ballou

Journal of Inorganic Biochemistry, 2000

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Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms

Christal Sohl

Archives of Biochemistry and Biophysics, 2011

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The kinetics of cytochrome P-450 reductase stimulation by ethylmorphine

Barry H Rumack, MD

Life Sciences, 1971

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Spectra and Kinetic Studies of the Compound I Derivative of Cytochrome P450 119

Xin Sheng

Journal of the American Chemical Society, 2008

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The catalytic mechanism of cytochrome P-450. Spin-trapping evidence for one-electron substrate oxidation.

H. Beilan, Ohara Augusto

1982

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Kinetic Isotope Effects in Hydroxylation Reactions Effected by Cytochrome P450 Compounds I Implicate Multiple Electrophilic Oxidants for P450-Catalyzed Oxidations

Xin Sheng

Biochemistry, 2009

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Aldehydic products of lipid peroxidation inactivate cytochrome P-450

Vyacheslav Buko

Experimental and Toxicologic Pathology, 1999

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Quantitative Production of Compound I from a Cytochrome P450 Enzyme at Low Temperatures. Kinetics, Activation Parameters, and Kinetic Isotope Effects for Oxidation of Benzyl Alcohol

Xin Sheng

Journal of the American Chemical Society, 2009

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Reaction profile of the last step in cytochrome P-450 catalysis revealed by studies of model complexes

Zeev Gross

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The mechanism of cytochrome P450-catalysed drug oxidations

V. Ullrich

Drug Action at the Molecular Level, 1977

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Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential

David Ballou

The Journal of biological chemistry, 1975

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Destruction of cytochrome P-450 by 2-isopropyl-4-pentenamide and methyl 2-isopropyl-4-pentenoate: Mass spectrometric characterization of prosthetic heme adducts and nonparticipation of epoxide metabolites

Bruce Mico

Archives of Biochemistry and Biophysics, 1979

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Cumene hydroperoxide effected hydroperoxidation by cytochrome P-450

David Gurka

Archives of Biochemistry and Biophysics, 1985

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Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes

Sason SHAIK

Chemical Reviews, 2004

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Overview: Some Basic Controversies and Applications of Cytochrome P450 Compound I

Zhian Xi

2021 5th International Conference on Computational Biology and Bioinformatics, 2021

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Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

Richard Mayer

Biochemical …, 1985

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Diversity in Mechanisms of Substrate Oxidation by Cytochrome P450 2D6. LACK OF AN ALLOSTERIC ROLE OF NADPH-CYTOCHROME P450 REDUCTASE IN CATALYTIC REGIOSELECTIVITY

Imad Hanna

Journal of Biological Chemistry, 2001

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Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities

Imad Hanna

Archives of Biochemistry and Biophysics, 1998

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Catalytic Activity of Cytochrome P-450 using NADP+ Reduced by an Anionic Hydride Organosiloxane

Jose Daniel Pluas Basurto

Scientia Pharmaceutica, 2008

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One oxidant, many pathways: a theoretical perspective of monooxygenation mechanisms by cytochrome P450 enzymes

Devesh kumar

Journal of Biological Inorganic Chemistry, 2004

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A Substituted Hypersensitive Radical Probe for Enzyme-Catalyzed Hydroxylations: Synthesis of Racemic and Enantiomerically Enriched Forms and Application in a Cytochrome P450-Catalyzed Oxidation

Imad Hanna

The Journal of Organic Chemistry, 1997

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MECHANISTIC ENZYMOLOGY OF OXYGEN ACTIVATION BY THE CYTOCHROMES P450

Roman Davydov

Drug Metabolism Reviews, 2002

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Suicidal inactivation of hepatic cytochrome P-450 in vitro by some aliphatic olefins

Gino Turchi

Biochemical and Biophysical Research Communications, 1982

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Novel Cytochrome P450 Bioactivation of a Terminal Phenyl Acetylene Group: Formation of a One-Carbon Loss Benzaldehyde and Other Oxidative Products in the Presence of N-Acetyl Cysteine or Glutathione

Janet Tam

Chemical Research in Toxicology, 2011

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Cytochrome P450scc-substrate interactions. Studies of binding and catalytic activity using hydroxycholesterols. J Biol Chem 257: 1876-1884

Robert Tuckey

Journal of Biological Chemistry

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Peroxidase-like activity of uncoupled cytochrome P450

David Ballou

Biochemical Pharmacology, 2012

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Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen

Mohamed Rashed

Chemical Research …, 1988

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Cytochrome P-450 heme moiety. The specific target in drug-induced heme alkylation

M. Correia, H. Beilan

The Journal of biological chemistry, 1981

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