Agreement between clinical and histopathological diagnoses of oral lesions (original) (raw)
Related papers
Clinical and histological diagnosis of oral pathologic lesions, any concordance?
African Journal of Oral Health, 2019
Objective: This study aims to examine the concordance between clinical and histopathological diagnosis of surgical specimen of oral lesions using partial biopsy technique. Methods: This was a retrospective study that utilized the data obtained from the case notes and histology record of 433 patients that had biopsy done between 2008 and 2017. Information on patients' age, gender, type of biopsy, presumptive clinical diagnosis and histopathologic diagnosis were obtained. Concordance between presumptive clinical and histopathologic diagnosis (incisional and final surgical specimen as the case may apply) and rate of misdiagnosis were assessed. Results: Excisional biopsies were more often used for benign lesions while incisional biopsy with or without surgical specimen were more often used for malignant lesions. Benign lesions were more frequently diagnosed than malignant lesions. The presumptive clinical diagnosis was erroneous for 40.3% and 22.1% of lesions following incisional histopathology and surgical specimen histopathology report respectively. Lesions that were subjected to both incisional and surgical specimen biopsies had a misdiagnosis rate of 11.2%. Conclusion: Incisional biopsy and post-surgical specimen histopathology investigation are important tools in the effective management of oral pathologic lesions.
Correlation between clinical and histopathologic diagnoses of potentially malignant oral lesions
Archive of Oncology, 2004
BACKGROUND: The serious nature of potentially malignant oral lesions (PMOL) demands that the final diagnosis be made on both clinical and histopathologic grounds. The aim of the present study was to determine the correlation between clinical and histopathologic diagnoses of PMOL using a discrepancy index (DI). METHODS: Fifty-one patients with PMOL were examined clinically, and a biopsy was taken from each one. The results of histopathologic diagnosis were compared with the clinical diagnosis. We established that the histopathologic diagnosis was incompatible when the clinical diagnosis was not confirmed. On the basis of the incompatible diagnosis, we calculated a discrepancy index between the clinical and histopathologic diagnosis. RESULTS: Clinically, the homogeneous leukoplakia was the most frequent lesion followed by erosive lichen planus and reticular lichen planus. No cases of erythroplakia were observed. Lesions were most frequently seen at the buccal mucosa, followed by the g...
The Spectrum of Oral Pathology Specimens: A Histopathologic Analysis of 442 Specimens
Jordan Medical Journal
Background Aims: Diseases of the oral cavity are heterogenous regarding their etiology, pathogenesis, histogenesis and clinical outcomes. The aim of this study was to examine the frequency of oral diseases encountered in our experience. Methods: The archives of pathology at Jordan University Hospital were retrospectively searched for oral cavity specimens from 2013–2020. Fisher’s exact test was performed to examine the statistical difference between the pathologic diagnosis and clinical variables. One-way ANOVA was used to analyze the differences in the mean of age between the different pathologic groups. Results: A total of four-hundred and forty-two cases were retrieved. There were 232 (52%) females and 210 (48%) males, ranging in age from 3–87 years (mean 43). Inflammatory and reactive diseases were the most common, constituting 147 (33%) of all specimens, followed by 139 (31%) benign neoplasms, 114 (26%) cysts, and 42 (10%) malignant diseases. Lichen planus was the most common i...
International Journal of Dentistry
Objective. Proper diagnosis plays a key role in the treatment and prognosis of all diseases. Although histopathological diagnosis is still known as the gold standard, final diagnosis becomes difficult unless precise clinical descriptions are obtained. So, this study aimed to evaluate the concordance of the clinical and histopathological diagnoses of all oral and maxillofacial biopsy specimens in a 12-year duration. Materials and Methods. Archive files and clinical findings related to 3001 patients who had been referred to the Department of Oral Pathology during a 12-year period were reviewed. The recorded information in files included age, sex, lesion’s location, clinical and histopathological diagnoses, and specialty of dentists. Results. Out of 3001 cases included and reviewed in this study, 2167 cases (72.2%) were consistent between clinical and histopathologic diagnoses. Age, sex, and clinician’s specialty were indicated to have no significant effect on diagnosis (p values = 0.5...
Agreement between clinical and histopathologic diagnoses and completeness of oral biopsy forms
Brazilian Oral Research, 2016
The present study aimed to assess the rate of agreement between clinical and histopathological diagnoses and to report the frequency of completed forms for specimens that were subjected to histopathological examination and retrospectively examined. Data from 8,168 specimens submitted to histopathological examination were retrieved from the records. A total of 5,368 cases were included. Agreement was defined based on the definition of lesion nature according to its diagnostic category. Sensitivity, specificity, and positive and negative predictive values were calculated for each diagnostic category. The highest rate of agreement was observed for periapical lesions (92.6%), followed by potentially malignant disorders (90.1%) and non-neoplastic proliferative disorders (89.3%). Low rates of histopathological confirmation of the clinical impression were observed for mesenchymal tumors (25.0%) and cysts (44.2%). Sensitivity values were > 0.70 for all lesions, except for cysts (0.51). Specificity was relatively high, ranging from 0.97 to 1.00. The frequency of incomplete biopsy forms ranged from 16.8% (malignant tumors of oral mucosal epithelium) to 51.0% (nonspecific inflammatory reaction). The most frequently completed biopsy forms corresponded to epithelial malignant tumors (83.2%) and glandular inflammation (72.3%). In conclusion, there was an acceptable level of agreement. The low level of completeness of biopsy forms indicates little awareness about the relevance of gathering detailed information during clinical examination.
Concordance Between Clinical and Histopathologic Diagnoses of Oral Mucosal Lesions
Journal of Oral and Maxillofacial Surgery, 2011
Background: Accurate diagnosis of orofacial tumours is important as this determines the treatment options as well as the eventual treatment outcome. Agreement between clinical and histopathological diagnosis becomes important in this regard. Aims: The aim was to determine the level of agreement between clinical and histopathology diagnosis of orofacial lesions. Method: This is a retrospective study of all histopathology reports seen at KATH maxillofacial unit. Thedata collected included, clinical diagnosis and histological diagnosis. Results: A total of 567 histopathology reports were evaluated. The percentage of agreement between clinical and histopathological diagnosis was 62.8%. Conclusion: The agreement between clinical and histopathological diagnosis was high. However clinicians cannot rely on only the clinical diagnosis in managing patients.
Histopathological Interpretation of Oral Cavity Lesions: Study at a Tertiary Care Hospital
IOSR Journals , 2019
Although the oral cavity lesions constitute only a small minority of pathological conditions, they are of great significance, as they have a potential to jeopardize the health and longevity of the patient. Among the various oral cavity lesions, oral cancer is a global health problem with increasing incidence and mortality rates. In India a vast majority of oral cancers are preceded by precancerous lesions & conditions caused by the use of tobacco in various forms. The aim of the present study is to know the spectrum and patterns of various oral cavity lesions at a tertiary care hospital, Ahmedabad, Gujarat, India. This is a one year study from June 2017 to May 2018. All the oral cavity specimens received in the Department of Pathology, GCS Hospital during the study period were included for the study. Data such as age, gender, and site of the lesion was collected. Data collected was analyzed. A total of 100 cases were analyzed during the study period. Age ranged from 2 to 78 years in the study. Overall male were affected more than the female with male:female (M:F) ratio of 3.5:1. Buccal mucosa (33%) was the commonest site involved followed by tongue (28%). Neoplastic lesions accounted for 69% cases and nonneoplastic accounted for 31% cases. Among the neoplastic lesion, squamous cell carcinoma (SCC) was seen in 40% cases; verrucous carcinoma in 6% and ameloblastic carcinoma in 1% cases; and adenosquamous carcinoma 1% cases. Most of the malignant lesions were located in the buccal mucosa (16%) and tongue (15%), followed by gingiva (6%),palate & floor of mouth (4%) each, lips (2%) alveolus (1%). Histology along with a detailed clinical work-up was found to be a useful, reliable and accurate diagnostic technique for lesions of oral cavity. A variety of lesions were encountered in the study with predominance of malignant lesions. Squamous cell carcinoma was the commonest malignant lesion.
2021
Background: Diseases of the oral cavity are heterogenous in etiology, pathogenesis, histogenesis and clinical outcome. Several epidemiologic studies exist in the literature with variable and conflicting results, based on small sized-samples and geographic factors. The aim of this study is to examine the frequency of oral diseases encountered in our experience from a tertiary hospital and to compare it with previous studies.Methods: The archives of pathology at Jordan University Hospital were retrospectively searched for specimens of oral cavity and related structures anatomic areas between 2013-2020. Fisher’s exact test was performed to examine the statistical difference between the pathologic diagnosis and clinical variables of age, gender and site of specimen. One-way ANOVA test was applied to analyzed the differences in the mean of age among different pathologic groups. P-value of less than 0.05 was considered significant.Results: A total of four-hundred forty-one cases were retr...
Histopathological Study of Tumor and Tumor Like Lesions of the Oral Cavity
Annals of Pathology and Laboratory Medicine, 2019
Background: The oral cavity is one of the most common site for various tumor and tumor like lesions. Development of oral cavity lesions are strongly linked with smoking. Hemangioma is the commonest benign tumor. Inflammatory fibrous hyperplasia is the commonest nonneoplastic reactive lesion. Squamous cell carcinoma (SCC) is most common among malignant lesions. Aims & Objectives: To study the histopathological patterns & variations of oral cavity lesions. Materials and Methods: A three year retrospective cross-sectional study by histopathological examination. Results: A total of 105 cases were subjected to histopathological examination. Among these, 28 cases (26.66%) were benign, 27 cases (25.71%) were malignant and 4 cases (3.80%) were pre-malignant lesions. Among the malignant lesions, SCC was most common (85.19%), while inflammatory fibrous hyperplasiawas most common among non-neoplastic lesions (45.65 %). Overall females were affected more than males (M: F=1: 1.1), though malignant lesions were more common in males. Malignant lesions were more common in older age group (mean age 52.26%), while non-neoplastic lesions were common in younger age group (mean age 37.87%). Malignant lesions were most common intongue (11 cases, 40.74 %), while benign lesions were most common in gingiva (10cases, 35.71%). Conclusion: A variety of benign and malignant tumors occur in oral cavity. However, the origin and nature of the oral cavity lesions cannot be confirmed by clinical examination alone. Hence, histopathological examination is essential to confirm the diagnosis and malignant potential of the oral cavity lesions.
To See the Histo-Pathological Pattern of Oral Mucosal Lesions
International Journal of Medical and Biomedical Studies, 2021
Background & Method: This prospective observational study was carried out with total number of patients 60 in the Department of Otorhinolaryngology and head and neck surgery, Amaltas Institute of Medical Sciences, Dewas, M.P., w.e.f. from August 2018 to September 2020. Patient was thoroughly investigated for complete haemogram, blood sugar, blood urea, serum creatinine, bleeding & Clotting time, coagulation profile, chest x-ray for any secondary focus. Result: Out of 35 cases of clinically premalignant lesions 30 cases were positive for malignant cells on histology. 5 were suspicious for malignant cells. Out of the 25 cases of clinically malignant lesions 25 cases were positive for malignant cells on histology and nil cases of suspicious for malignancy. In this present study, on histopathology premalignant lesions was found in 8.33% and malignancy was seen 91.66% cases. On histopathological examination, squamous cell carcinoma was the most common type among all cases (78.33%). I...