Comparison of Shrimp (Litopenaeus Vannamei) Shell Paste and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-Acp) Paste as Teeth Remineralization Material (original) (raw)
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International Journal of Applied Pharmaceutics, 2019
Objective: To determine the comparison of shrimp shell and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) as tooth remineralization material. Methods: This study was an experimental laboratory with a cross-sectional design. Study sample was 10 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 h, then assessed with energy dispersive spectroscopy (EDS). Samples were divided into 2 groups: 5 samples were applied using CPP-ACP paste and 5 samples using shrimp shell paste every 8 h for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to compare shrimp shell paste and CPP-ACP paste as tooth remineralization material. Results: The result of this study showed p>0.05, meaning there was no significant difference between CPP-ACP and shrimp shell paste mineral composition. Conclusion: Shrimp shell paste has an effective value to be used as a tooth remineralization material.
Journal of Dentomaxillofacial Science, 2018
The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptideamorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Material and Methods: This study was an experimental laboratory with cross sectional design. Study sample was 15 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 hours, then assessed with Energy Dispersive Spectroscopy (EDS). Samples were divided into 3 groups: 5 samples were applied using blood clam (anadara granosa) shell paste, 5 samples using shrimp shell paste and 5 samples were applied using CPP-ACP paste every 8 hours for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to see comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Results: The result of this study showed P> 0.05 which means there was no significant difference between blood clam shell paste, shrimp shell paste and CPP-ACP mineral composition. Conclusion: Blood clam shell paste and shrimp shell paste has an effective value to be used as tooth remineralization material.
International Journal of Applied Pharmaceutics, 2019
Objective: To determine the increase of tooth enamel surface hardness after application hydroxyapatite paste that was synthesized from blood cockle shells (Anadara granosa) as a remineralization agent. Methods: Laboratory experimental study using twenty-seven maxillary first premolar and randomly divided into 3 groups. All of the samples were immersed in the non-cola carbonated drink (2 min). Thereafter, samples in each group were treated (6 min) with application of blood cockle shells paste that has been synthesized (group 1), casein phosphopeptide-amorphous calcium phosphate paste (GC Tooth Mousse®) (group 2) as a positive control, and stored in saline solution (NaCl) (group 3) as a negative control. Vickers Hardness Number (VHN) measurement was performed at baseline, after immersing in non-cola carbonated drink and after completing of the respective treatment. Results: Immersion in non-cola carbonated drink reduced the enamel surface hardness significantly. Significant re-hardening after treated occurred in group 1 and 2 also baseline hardness of both groups were achieved. But statistically no significant differences between group 1 and 2 in rehardening enamel surface hardness (final hardness-hardness after immersion). Conclusion: Application of blood cockle shells paste as a remineralization agent could increase tooth enamel surface hardness which is nearly the same effective as CPP-ACP paste.
International Journal of Applied Pharmaceutics, 2024
Objective: Caries is a multifactorial disease that affects most of the world's population and is a detrimental factor for oral health. Demineralization on teeth can reduce the hardness of the enamel surface, which causes enamel to be susceptible to caries. The purpose of this study was to determine the effect of giving 15% hydroxyapatite paste from goldfish scales (Cyprinus carpio) with CPP-ACP as a remineralizing agent on the enamel surface hardness. Methods: This laboratory experimental study using 24 samples of post-extraction maxillary first premolars. There were 4 groups of samples, group I samples that were not given the test material were only soaked in artificial saliva, group II samples were only demineralized with HCl solution for 120 seconds, both test groups were then demineralized with HCl solution for 120 seconds before being given the test material. Group III samples were applied with the test material CPP-ACP for 2 min; group IV samples were applied with 15% goldfish scale hydroxyapatite paste (Cyprinus carpio) for 2 min. Both test groups were given treatment for 14 consecutive days. All sample groups were tested for surface hardness using the Microvickers Hardness Tester. Results: The results of the Mann-Whitney analysis test showed that there was a significant difference in the effect of pn<0.05 between each group studied. Based on the results of the study, there was an effect after administration of 15% hydroxyapatite paste of goldfish scales (Cyprinus carpio) with CPP-ACP as a remineralizing agent on enamel surface hardness. Conclusion: Based on the results of research on the effect of administering 15% goldfish (Cyprinus carpio) scale hydroxyapatite paste with Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on enamel surface hardness, it can be concluded that there is a significant effect after administering goldfish (Cyprinus carpio) scale hydroxyapatite paste 15 % and CPP-ACP on enamel surface hardness.
International Journal of Biomaterials, 2015
Crab's shells of Portunus pelagicus species were used as raw materials for synthesis of hydroxyapatite were used for protection against demineralization of teeth. Calcination was conducted to crab's shells of Portunus pelagicus at temperature of 1000 ∘ C for 5 hours. The results of calcination was reacted with (NH 4 ) 2 HPO 4 , then dried at 110 ∘ C for 5 hours. Sintering was conducted to results of precipitated dried with temperature variations 400-1000 ∘ C for a hour each variation of temperature then characterized by X-ray diffractometer and FTIR in order to obtain the optimum formation temperature of hydroxyapatite is 800 ∘ C. The hydroxyapatite is then tested its effectiveness in protection against tooth demineralization using acetate buffer pH 5.0 with 1 M acetic acid concentration with the addition of hydroxyapatite and time variation of immersion. The results showed that the rate of tooth demineralization in acetate buffer decreased significantly with the provision of hydroxyapatite into a solution where the addition of the magnitude of hydroxyapatite is greater decrease in the rate of tooth demineralization.
Journal of applied oral science : revista FOB
Dental applications based on the unique characteristics of amorphous calcium phosphate stabilized by casein phosphopeptides (CPP-ACP) have been proposed, as well as the improvement of its properties. The objective of this study was to determine the ability of topically applied CPP-ACP from a commercial product to remineralize subsurface lesions when applied for extended periods of time (3 h and 8 h). Artificially induced carious lesions were produced in 50 bovine enamel blocks previously selected by surface hardness. After treatments with gel without F and CPP-ACP applied for 1 minute (Placebo); 2% NaF neutral gel applied for 1 minute (Fluoride 1 min); CPP-ACP applied for 3 min (ACP 3 min); and CPP-ACP applied for 3 h (ACP 3 h) and for 8 h (ACP 8 h), the enamel blocks were submitted to the remineralization pH-cycling. Surface hardness and synchrotron micro-tomography were used to determine the percentage of surface hardness recovery (%SHR) and to calculate mineral concentration (gHA...
2016
Blood clam shells (Anadara granosa) was used as a raw material. Synthesis of hydroxyapatite was utilized for dental remineralization. Calcination was carried out to clam shell species Anadara granosa at 1100°C for 5 hours. The calcination result was reacted with (NH4)2HPO4, then dried at 110 °C for 5 hours. Sintering was conducted on dry precipitates that produced at 800 °C for 2 hours. The size of the obtained Hydroxyapatite was 7.66507 nm. Hydroxyapatite was then tested for its effectiveness for the remineralization of tooth using acetate buffer pH 5.0 with acetic acid 1 M with variations of immersion time and the hydroxyapatite addition. The results showed that the rate of dental remineralization in acetate buffer has increased significantly with the provision of hydroxyapatite into a solution in which the greater the addition of hydroxyapatite, the greater the rate increase of tooth remineralization. Keyword: clam shells, hydroxyapatite, remineralization. INTRODUCTION Nanopartic...
IOSR Journals , 2019
Aim of the study was to assess and compare the effect of calcium sucrose phosphate and calcium casein phosphopeptide containing pastes on mineralization of artificially demineralized human enamel. The remineralizing ability of calcium sucrose phosphate and calcium casein phosphopeptide is under research.75 extracted premolar teeth were collected and a buccal window was exposed on the tooth sample by coating the rest of the teeth with nail varnish. The samples were artificially demineralized using Featherstone pH cycling technique. The medicaments were applied to the demineralized samples for 5 minutes, rinsed and then stored in de-ionized water for the next day. This was repeated for15 days. The samples were excited using diode laser and the fluorescence spectra were measured using laser induced fluorescence spectroscopy (LIFS).Both groups showedremineralization. Calcium sucrose phosphate induced the highest remineralization in the tooth samples. Calcium casein phosphopeptide showed less remineralization than calcium sucrose phosphate. The difference in remineralization showed by the pastes was statistically significant. So they may have a potential role as a remineralizing agent for daily use
Brazilian Research in Pediatric Dentistry and Integrated Clinic, 2019
Objective: To evaluate and compare the remineralization potential of a dentifrice containing bioactive glass and a topical cream containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in remineralizing artificial carious lesion on enamel. Material and Methods: Forty-five freshly extracted human permanent premolar teeth were selected. Samples were divided into three groups: GI-regular tooth paste without specific remineralizing agent; GII-tooth paste containing calcium sodium-phosphosilicate (novamin) and GIII-topical cream containing casein phosphopeptide-amorphous calcium phosphate. All the sound enamel samples were viewed under scanning electron microscope (SEM) to assess the topographical pictures of enamel surface and energy dispersing x-ray analysis (EDAX) was done to estimate quantitatively the amounts of mineral (calcium and phosphorous). The mineral content of calcium and phosphorus after demineralization in each group was noted. The samples were then subjected to SEM and EDAX. Results: GI does not show any increase in the calcium and phosphorus after applying toothpaste without any remineralizing agent but GII and GIII showed a net increase in calcium and phosphorous values after applying concern-remineralizing agents. Inter group comparison showed GIII yield higher net calcium and phosphorous values than GII. Conclusion: Two remineralizing agents showed remineralization potential on enamel surfaces. Casein phosphopeptide-amorphous calcium phosphate showed better remineralizing potential than calcium sodium phosphosilicate. Hence CPP-ACP can be considered as the material of choice in remineralizing early enamel carious lesions.
World Journal of Dentistry, 2023
Original research calcium and phosphate that aids in remineralization. Later, fluoride (0. 09%) was added to CPP-ACP, resulting in casein phosphopeptideamorphous calcium phosphate fluoride (CPP-ACPF) paste. CPP-ACPF has a greater remineralization capability than CPP-ACP. However, these commercial remineralizing agents have certain disadvantages such as; short duration of action, providing only superficial remineralization, causing gastric irritation, allergies and are not viable for the low-income population. 5 Over the years, various natural alternatives have been preferred such as corals, mollusks, egg shells, Moringa oleifera, fish, algae etc.