De novo mitral regurgitation as a cause of heart failure exacerbation in patients with hypertrophic cardiomyopathy (original) (raw)

2018, International Journal of Cardiology

AI-generated Abstract

This observational study investigates the incidence of de novo severe mitral regurgitation (MR) contributing to heart failure exacerbations in patients with hypertrophic cardiomyopathy (HCM). By analyzing a registry of HCM patients at the Sheba Medical Center, the research highlights a significant association between acute clinical deterioration and newly developed MR, which is independent of the commonly observed systolic anterior motion of the mitral valve. Findings underscore the importance of monitoring mitral valve function in stable HCM patients to anticipate potential heart failure complications.

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