Linear atrophoderma of Moulin located on the face (original) (raw)
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Linear Atrophoderma of Moulin Localized to Face: An Exceedingly Rare Entity
Journal of Skin and Stem Cell, 2020
Introduction: Linear atrophoderma of Moulin (LAM) is a rare dermatologic disorder characterized by hyperpigmented atrophic plaques following the Blaschko lines (BL). The trunk and limbs are the usual sites affected. Isolated facial involvement is an exceedingly rare entity. Despite a comprehensive medical literature search, the author could find only two cases of LAM where the lesions are exclusively localized to the face. In this article, the author presents the third case of LAM localized to face only. Case Presentation: A 26-year-old male complained of multiple linear non-pruritic pigmented lesions over the left side of the nose and glabellar area of six months’ duration. There was no history of erythema, thickening/hardening of skin, or violaceous border surrounding the lesions. On clinical examination, there were multiple hyperpigmented brownish lesions, the majority of which were depressed, involving the left ala and bridge of nose laterally and glabellar area in a Blaschkoid ...
Linear atrophoderma of Moulin on the neck
Journal of Dermatological Case Reports, 2011
Background: Linear atrophoderma is a rare disease, first described by Moulin in 1992 in 5 patients. It is an acquired unilateral hyperpigmented, depressed band-like areas following the lines of Blaschko. It affects children or adolescents of both genders involving the trunk or the limbs. It is considered to be a rare cutaneous form of mosaicism. Main observation: A 39-year-old woman with a 22 years history of unilateral slightly depressed hyperpigmented lesion on her neck was admitted to us. The skin texture was normal and there were no signs of induration or sclerosis. The histopathological examination revealed a normal epidermis outlined by a hyperpigmented basal layer. In the papillary dermis proliferation of superficial vessels with mild lymphocytic infiltrate and melanin-laden macrophages were present. The collagen fibres and elastic fibres were normal. The clinical and histopathological features confirmed the diagnosis of linear atrophoderma of moulin. We discussed the case according to the other cases reported in the literature. Conclusion: Approximately 28 cases of linear atrophoderma have been reported in literature. The present case has the charecteristic clinical and histopathological features of linear atrophoderma as defined by Moulin, but the localization of the lesion is unusual.
Linear atrophoderma of Moulin together with leuconychia: a case report
Journal of The European Academy of Dermatology and Venereology, 2006
Linear atrophoderma of Moulin has a distinctive disease pattern characterized by hyperpigmented atrophoderma and was described originally in 1992. It follows the line of Blaschko, and occurs without preceding inflammation, subsequent induration or scleroderma. The lesions usually develop during childhood or adolescence, and the prognosis is good. The diagnosis is made clinically and histopathologically. In our 18-year-old male patient, there were atrophic plaques unilaterally located on the trunk and arm, and white discoloration on all finger nails. Histopathological examination revealed epidermal atrophy together with disruption of collagen fibres.
Linear atrophoderma of Moulin: a disease which follows Blaschko's lines
British Journal of Dermatology, 1996
Linear atrophoderma of Moulin is a distinctive disease pattern characterized by hyperpigmented atrophoderma and described originally in 1992. It follows the lines of Blaschko. and occurs wilhotil preceding inflammation, subsequent induration or scleroderma. The lesions usually develop during childhood or adolescence, and the prognosis is good. The differential diagnoses include lint-ar dermatoses. e.g. linear scleroderma. epidermal naevi. Inflammatory linear verrucous epidermal naevus. lichen striatus. Blaschkitis acuta. reticulate hyperpigmentation of Iijima and linear lupus erythematosus. Diagnosis is made clinically and histologically. We report a 22-year-old woman with a 1 7 year history of linear atrophoderma which involved the right arm and trunk.
Linear atrophodrma of Moulin: a case report and review of the literature
Dermatology Practical & Conceptual, 2013
Case presentation A 17-year-old girl presented with a six-month history of multiple asymptomatic brownish atrophic plaques in a zosteriform distribution on the left side of her trunk (Figure 1). There was no family history of a similar skin disease. Laboratory studies were unremarkable for any chronic or autoimmune disorder. Biopsy of a lesion showed a normal epidermis with increased pigmentation of the basal layer and a broad dermis with thickened collagen fibers and diminished periadnexal and subcutaneous fat tissue (Figures 2, 3, 4). Clinical and dermatopathologic findings were compatible with atrophoderma of Moulin. The use of topical steroids and tacrolimus as a second-line regimen did not result in any improvement of lesions. Discussion Linear atrophoderma is a rare, acquired, linear dermatosis. It is named after Moulin, who, in 1992, reported on five patients with pigmented and more or less atrophic bands along Blaschko's lines [1]. The age of onset in the first described cases ranged from 6 to 20 years. Lesions were unilateral, forming a recumbent "S" pattern, and the intensity of pigmentation and atrophy was variable. They remained stable throughout an observation period of 2 to 30 years. Of the skin biopsies performed on three patients, there was only irregular and moderate hyperpigmentation of the basal layer. In the dermis, there was no distinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical
International Journal of Dermatology, 2005
A 14-year-old boy had a history of asymptomatic, unilateral brown streaks of 5 years' duration on the left side of the trunk and left upper limb. No prior inflammation or any preceding eruption was observed. The streaks extended in distribution during the first few months but then stabilized. His medical and family history was unremarkable.
Linear atrophoderma of Moulin: a disease related to immunity or a kind of connective tissue disease?
The Australasian journal of dermatology, 2016
We describe a 28-year-old man with linear atrophoderma of Moulin (LAM), whose serum immunological markers were abnormal (including antinuclear antibody, ribonucleoprotein, immunoglobulin M and anti-SM antibody). In addition, however, a histological analysis identified unexpected connective tissue disease changes in this patient. We speculate that the pathogenesis of LAM is associated with immunity or that LAM itself is a kind of connective tissue disease.