Role of arachidonic acid metabolism in human platelet activation and irreversible aggregation (original) (raw)

Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets

Valentina Shpakova

Thrombosis Research, 2018

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Investigation of cyclooxygenase and signaling pathways involved in human platelet aggregation mediated by synergistic interaction of various agonists

Bassem S H A B A N Sadek

Drug Design, Development and Therapy, 2015

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Measurement of arachidonic acid liberation in thrombin-stimulated human platelets. Use of agents that inhibit both the cyclooxygenase and lipoxygenase enzymes

Gerard Mauco

Biochimica et biophysica acta, 1985

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Inhibition by sulfhydryl agents of arachidonic acid-induced platelet aggregation and release of potential inflammatory substances

Bernardo Vargaftig

Prostaglandins, 1974

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Effect of eicosatetraenyl (3-aminopropyl) phosphonate (URI-73A) on platelet aggregation and arachidonic acid metabolism

Raffaele Landolfi

Prostaglandins, …, 1983

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Effects of a trans isomer of arachidonic acid on rat platelet aggregation and eicosanoid production

jean-louis sebedio

The Journal of Lipid Research

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Involvement of Nitric Oxide on Calcium Mobilization and Arachidonic Acid Pathway Activation during Platelet Aggregation with different aggregating agonists

Sahana Mazumder

International journal of biomedical science : IJBS, 2016

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Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation

W. Siess

The Journal of biological chemistry, 1983

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Serine esterase inhibitors block stimulus-induced mobilization of arachidonic acid and phosphatidylinositide-specific phospholipase C activity in platelets

Jack Vanderhoek

Journal of Biological Chemistry, 1980

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Rapid inactivation of cyclooxygenase activity after stimulation of intact platelets

Eduardo Lapetina

Proceedings of the National Academy of Sciences, 1979

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Arachidonic Acid Metabolism in Endothelial Cells and Platelets

Nazmul Islam

Annals of The New York Academy of Sciences, 1982

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Triggering by Paf-acether and adrenaline of cyclo-oxygenase-independent platelet aggregation

Bernardo Vargaftig

British Journal of Pharmacology, 1984

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Effects of adenosine 3′:5′-monophosphate and platelet aggregation on thromboxane biosynthesis in human platelets

Hans-erik Claesson

FEBS Letters, 1979

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Requirement of ADP for arachidonic acid-induced platelet aggregation: studies with selective thromboxane-synthase inhibitors

Chiara cerletti

Biochemical Pharmacology, 1986

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Influence of calcium-channel blockers on platelet function and arachidonic acid metabolism

JAY MEHTA

American Journal of Cardiology, 1985

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Why do some β adrenergic agonists inhibit generation of thromboxane A2 in incubates of platelets with arachidonic acid?

Bernardo Vargaftig

Biochemical Pharmacology, 1978

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Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change

W. Siess

The Journal of biological chemistry, 1984

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Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products

Anna Falanga

Blood, 1984

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Covalent binding of arachidonic acid metabolites to human platelet proteins. Identification of prostaglandin H synthase as one of the modified substrates

Marc Lecomte

Journal of Biological Chemistry, 1990

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Inhibition of release of arachidonic acid by monodansylcadaverine during activation of human platelets by collagen

Hwa-Jin Park

Agricultural and Biological Chemistry, 1986

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Modulation of platelet function by reactive oxygen metabolites

Giuseppe Ambrosio

1994

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Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways

Huma Rasheed

Acta pharmacologica Sinica, 2003

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Arachidonic acid metabolism in platelets and endothelial cells

Babette Weksler

Progress in Lipid Research, 1981

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The role of inhibition of nitric oxide synthesis in the aggregation of platelets due to the stimulated production of thromboxane A2

Sahana Mazumder

Blood Coagulation & Fibrinolysis, 2014

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Synergistic effect of PGE1 and the calcium antagonist verapamil in disaggregation of aggregated platelets and inhibition of platelet aggregation induced by PAF-acether or arachidonic acid

Yaw Oppong

Progress in Lipid Research, 1986

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The key contribution of platelet and vascular arachidonic acid metabolism to the pathophysiology of atherothrombosis

Bianca Rocca

Cardiovascular Research, 2021

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Inhibitory effect of stearidonic acid (18∶4 n−3) on platelet aggregation and arachidonate oxygenation

Michel Lagarde

Lipids, 1989

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The Effects of Vanilloid-Like Agents on Platelet Aggregation

Murray Adams, Kiran Ahuja

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Oxidative pathways of arachidonic acid as targets for regulation of platelet activation

Andrés Trostchansky

Prostaglandins & Other Lipid Mediators, 2019

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Phorbol esters sensitize platelets to activation by physiological agonists

W. Siess

Blood, 1987

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Ionophore A-23187- and thrombin-induced platelet aggregation: independence from cycloxygenase products

Eduardo Lapetina

Proceedings of the National Academy of Sciences, 1978

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Low concentrations of reactive γ-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation

Jennifer Lefils, Michel Guichardant, Michel Lagarde

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2009

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