Demographical Distribution on the Incidence of Helicobacter pylori Infection in Jakarta: Obtaining Samples from 5 Municipalities (original) (raw)
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Burden of Helicobacter Pylori (H. Pylori) Disease in a Community in Sokoto State
Archives of Immunology and Allergy, 2018
Pyloric ulcer a public health disease important and is highly implicated with H. pylori hence the research to determine the prevalence of helicobacter pylori (H. pylori), induced peptic ulcer in sokoto metropolis. The sample for the study consisted of 150 (one hundred and fifty) adults’ females/males randomly drawn. Data collected were analyzed using descriptive statistic of frequency count, normative percentage and grand mean; as well as inferential statistics of chi-square (χ2). The level of significant was fixed at 0.05. Appropriate degrees of freedom were worked out. The antibody rapid test device (whole blood/serum/plasma) is a qualitative device based on immunoassay for the detection of H. pylori antibodies in the whole Blood, serum or plasma. In this test specimen followed by buffer is added to the specimen well of the test device. The specimen migrates chromatographically along the length of the test strip contained within the device and interacts with the reagents on the test strip.This research showed that prevalence of H.pylori infection is 38(25.3%). Among the 82 male’s clients 20(24%) tested positive, while among 68 females 18(26%) tested positive to H. pylori.There was a significance difference of the calculated chi-square (χ2=32.33 is greater than the tabulated χ2=3.841 at df=1, p<0.05). The prevalence of H. pylori induced ulcer among 93 symptomatic clients 21(22.8%) tested positive, while among 57 asymptomatic clients 17(29.8%) tested positive. There was a significance difference of the calculated chi-square (χ2=33.57 is greater than the tabulated χ2=3.841 at df=1, p<0.05). This may explain why the rate of infection is so high in poorer countries and in socio-economic groups since It is potentially spread by fecal contamination, characterized by crowded living conditions, poor sanitary conditions, and lack of clean water (Bujanover, 1996). Poor Personal hygiene is also very important since food preparers who may not perform adequate hand washing may be potential sources of infection (Hunt, 2011).
Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines
Annals of clinical microbiology and antimicrobials, 2004
Helicobacter pylori diagnosis and susceptibility profile directs the applicability of recommended treatment regimens in our setting. To our knowledge, there is no published data on the culture and local susceptibility pattern of Helicobacter pylori in the Philippines. 52 dyspeptic adult patients undergoing endoscopy from the Outpatient Gastroenterology clinic of the University of the Philippines-Philippine General Hospital underwent multiple gastric biopsy and specimens were submitted for gram stain, culture, antimicrobial sensitivity testing, rapid urease test and histology. Antimicrobial susceptibility testing was done by Epsilometer testing (Etest) method against metronidazole, clarithromycin, amoxicillin, and tetracycline. Sixty percent (60%) of the study population was positive for H. pylori infection (mean age of 44 years +/- 13), 70% were males. H. pylori culture showed a sensitivity of 45% (95% CI [29.5-62.1]), specificity of 98% (95%CI [81.5-100%]), positive likelihood rati...
The current study was aimed to observe the prevalence of Helicobacter pylori infection at District Mardan with respect to their gender and age groups. The blood samples were collected from all the subjects who attended the OPD at Mardan Medical Complex. All these samples were screened for the presence of antibodies against H. pylori through a rapid antibody assay. Positive and negative cases were recorded based on the test results and prevalence was measured keeping in mind the selected parameters in individuals of each group. A total of 4312 people was included in the study, out of which 2586 were males and 1726 were females. Majority of the patients were in the mature age group. Based on our results, there were 125 males demonstrating a prevalence of 4.83% which is slightly higher than 4.66% prevalence of 77 females infected. Comparisons were made based on gender and age groups and data presented in the form of figures and tables. Monthly wise prevalence has also been shown. Moreover, prevalence was higher in the people aged 19-44 and lowest in immature ones. However, the overall prevalence in the subjects was 4.68% for the span of 4 months.
Malaysian Journal of Medicine and Health Sciences , 2015
To study the prevalence of Helicobacter Pylori (H. pylori) infection, according to ethnicity, gender and endoscopic findings among the patients underwent the oesophago-gastro-duodenoscopes (OGDS) at gastroenterology endoscopy unit, Hospital Serdang, Selangor, Malaysia. The database of all whom underwent OGDS at the gastroenterology endoscopy unit, Hospital Serdang from 1 st August 2010 to 31 st July 2012 was collected and assessed, retrospectively. A total of 924 patients who underwent OGDS were analyzed for the H. pylori infection by using Campylobacter-like organism (CLO) test. 130 (14.07%) tested positive, and their data were further studied according to gender, ethnicity, age group, initial indication for OGDS and endoscopic finding. The prevalence rate among males was 15.15% (70/462), while it was 12.99% (60/462) among females. In terms of ethnics, H. pylori infection was commonly found among Indian and Chinese with prevalence rate of 25.13% (50/199) and 17.41% (51/293) respectively. These figures are significantly higher than the 6.01% (25/416) for Malays. The age group (31-50 years old) had the highest prevalence rate of H. Pylori infection, which is of 18.55% (41/221). No significant difference was observed among initial indications for OGDS. Erosions were the commonest finding in H. pylori positive group with rate of 51.54% (67/130). However, erosions were not uncommon in H. pylori negative group as well with the rate of 48.61% (386/794). H. pylori infection rate among Malaysians was generally low, with the highest rate in Indians, followed by Chinese and relatively low in Malays. No significant difference between the prevalence rate of H. pylori infection in male and that in female was found. Erosions were equally common in either H. pylori positive or H. pylori negative group.
BMC Infectious Diseases, 2019
Background: More than 50% of the people are infected worldwide with H. pylori which causes significant public health morbidity and mortality. The distribution is quite different from country to country. Hence, early information is very important to prevent upper gastrointestinal complications. The current study aimed to assess the magnitude of H. pylori and associated risk factors among symptomatic patients attending at Jasmin internal medicine and pediatrics specialized private clinic from August 2017 until May 2018 in Addis Ababa city, Ethiopia. Methods: A cross-sectional study was conducted among 487 patients with upper gastrointestinal tract complaints attending at Jasmin internal medicine and pediatrics specialized private clinic from August 2017 until May 2018. Convenient sampling technique was used to enroll participants. Information regarding to risk factors was assessed using structured questionnaire. Stool samples were collected for H. pylori antigen test. Data was entered and analyzed using SPSS version20 statistical software and a p-value less than 0.05 was considered as statistically significant. Results: The overall prevalence of H. pylori among participants using stool antigen was 36.8% (n = 179/487). Regarding to family income status, those who have low monthly income were more likely to be infected with H. pylori infection (AOR = 6.056, CI 95% = 1.603-22.881, P = 0.037). In addition, families with low educational level were more likely to be infected with H. pylori infection than higher level education (AOR = 4.150, CI95% = 1.059-16.270, P = 0.041). Number of family members in the household , type of toilet they used and source of drinking water were not significantly associated with H. pylori infection. Conclusions: The prevalence of H. pylori infection was 36.8% and it was related to low income and low education levels. This finding calls for improving the socioeconomic status of the community. Moreover, further studies are needed to investigate potential risk factors for H. pylori infection.
Health services research and managerial epidemiology, 2024
Background: Around half of the world's population is infected with Helicobacter pylori (H. pylori), according to data from a recent systematic review. H. pylori infection is extremely common around the world. It is the most prevalent disease in Ethiopia and contributes to both morbidity and mortality. Patients with gastritis, peptic ulcers, and stomach cancer have been reported to harbor H. pylori. Objective: The aim of this study was to determine the trends of Helicobacter Pylori infection among patients attending the Bule Hora University Teaching Hospital from 2018-2022, Bule Hora, Ethiopia. Method: A hospital-based retrospective study design was conducted to recruit 314 sampled data from the logbook, which were five-year data (2018-2022) from the Bule Hora University Teaching Hospitals. Data were extracted using structured checklists. The sample size was calculated using the single-population proportion formula. Study participants were selected using a systematic random sampling technique. Data were entered in EpiData 4.6 and exported to SPSS Version 26 for analysis. Results: Approximately 314 complete data from selected participants were collected and evaluated for the present study. The mean age was 29.01 (SD ± 4.93). Most of the respondents (39.2%) were in the age group of 21 to 30 years. The general prevalence of H. pylori observed in this study is 28% (95% confidence interval [CI], 23-32.9). The prevalence was higher in women (71.6%) than in men (28.4%). In terms of age category, those over 60 years of age were observed with the highest positiveness for H. pylori with 38.1% and the trend of H. pylori prevalence fluctuated from 2018 to 2022. Conclusion: In total, 28% of the study participants had H. pylori, but there was variation in the prevalence of H. pylori infection between 2018 and 2022. Compared to other age groups, the 60-year-old age group had a higher prevalence of H. pylori and this prevalence continued to increase annually. The concerned parties must be interested in raising awareness and establishing criteria for the eradication of these bacteria. Keywords: Bule hora teaching hospital; Helicobacter pylori; sero status.
Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy
Objective: Helicobacter pylori (H. pylori) is a Gram-negative microaerophilic bacterium that is associated with diseases such as peptic ulcer, chronic gastritis, gastric MALT lymphoma, and gastric cancer. H. pylori infection is more common in developing countries. The high socioeconomic conditions and elimination of bacterial carriage by antimicrobial treatment reduce the prevalence of H. pylori in developed countries. The fecal H. pylori antigen test has been widely used recently. This test with high sensitivity and specificity constitutes a significant diagnostic method alternative due to its cost-effectiveness and rapid results. In this study, we retrospectively analyzed the presence of H. pylori antigen in the stool samples of patients with gastroduodenal complaints from laboratory records. Methods: Test results of patients who underwent H. pylori antigen rapid cassette test from fresh fecal samples between January 2018 and May 2022 in the Medical Microbiology Laboratory were included in the study. Fresh fecal samples from patients were analyzed using H. pylori Antigen Rapid Test Cassette (Acro Biotech Inc, USA) kits. The statistical analysis of the research was made with IBM-SPSS 25.0 (IBM Co., USA). The chi-square test was used to evaluate the research data. P<0.05 value was considered statistically significant. Results: A total of 5,718 patients, 3,285 (57.5%) women with gastroduodenal complaints, were included in the study. Fecal H. pylori antigen test positivity was determined in 1,429 (25%) of these patients. The antigen positivity rate was found to be higher in women (26.6%) compared to men (22.9%) (p<0.05). In addition, this rate was higher in adult patients (27.4%) than in pediatric patients (10.1%). In addition, this rate was higher in adult patients (27.4%) compared with pediatric patients (10.1%) (p<0.01). Conclusion: The regional prevalence data are informative about the development levels of countries in socioeconomic issues such as urbanization, infrastructure services, and access to clean water. In addition, these data may provide insight into the future prevalence of H. pylori-related diseases. We think that this study, in which the data of our region is shared, contributes to the literature.
Clinical Epidemiology and Global Health, 2021
Objective: H. pylori infection remains a major public health challenge. Our study aimed to determine the prevalence of H. pylori infection among the local population of the Timergara city in Lower Dir District of Pakistan and investigating the common risk factors associated with disease development. Methods: Between September 2016 to January 2017, 520 individuals have involved in this study. A venous blood sample along with questionnaire data was collected from each participant and H. pylori infection investigated using Indirect Enzyme-Linked ImmunoSorbent Assay. Results: Out of 520 persons studied, 115 (22.1%) were positive and 405 (77.9%) were negative. The majority of infected individuals were males 79 (29.4%) compared to females 34 (14.3%), P value˂0.000. The probability of H. pylori infection was more among smokers 32 (33%), snuff addictive 29 (35.8%), and regular soft drinks takers 57 (43.5%). Furthermore, the logistic regression revealed that the odds of developing H. pylori infection were significantly higher in males (AOR:2.