Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver (original ) (raw )Control of Heme Oxygenase and Plasma Levels of Bilirubin by a Synthetic Heme Analogue, Tin-Protoporphyrin
Karl Anderson
Hepatology, 1984
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The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin
George Drummond
Proceedings of the National Academy of Sciences, 1985
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Sn-protoporphyrin rapidly and markedly enhances the heme saturation of hepatic tryptophan pyrrolase. Evidence that this synthetic metalloporphyrin increases the functional content of heme in the liver
Mohinder Sardana
Journal of Clinical Investigation, 1985
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In vitro inhibition of heme oxygenase isoenzymes by metalloporphyrins
Ronald Wong
Journal of Perinatology, 2011
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Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation
George Drummond
Proceedings of the National Academy of Sciences, 1981
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Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism
Mohinder Sardana
Archives of Biochemistry and Biophysics, 1987
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Control of heme metabolism with synthetic metalloporphyrins
George Drummond
Journal of Clinical Investigation, 1986
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Properties of human kidney heme oxygenase: Inhibition by synthetic heme analogues and metalloporphyrins
Pavel Martasek
Biochemical and Biophysical Research Communications, 1988
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Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources
George Drummond
The Journal of experimental medicine, 1987
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Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis
Bo Angelin , Rolf Hultcrantz
Gut, 1990
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Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications
George Drummond
Journal of Clinical Investigation, 1985
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Systemic Effects of Orally-Administered Zinc and Tin (IV) Metalloporphyrins on Heme Oxygenase Expression in Mice
Christopher H Contag
Pediatric Research, 2006
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Retinoic Acid in Association with Tin-Metalloporphyrins Influences Heme Metabolism in vivo in Rats
Ramesh Prof Chandra
International Journal for Vitamin and Nutrition Research, 1999
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The Effect of Tin (IV)-Protoporphyrin-IX on Bilirubin Production and Excretion in the Rat
Lawrence Gartner
Pediatric Research, 1987
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Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production
George Drummond
Journal of Clinical Investigation, 1985
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Modulatory influence of tin-protoporphyrin on gossypol-induced alterations of heme oxygenase activity in male wistar rats
Ramesh Prof Chandra
European Journal of Drug Metabolism and Pharmacokinetics, 2003
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Suppression of hyperbilirubinemia in the rat neonate by chromium-protoporphyrin. Interactions of metalloporphyrins with microsomal heme oxygenase of human spleen
George Drummond
The Journal of experimental medicine, 1982
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Interaction of porphyrins with heme proteins – a brief review
Abhay Chakraborti
2003
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Effects of Metalloporphyrins on Heme Oxygenase-1 Transcription: Correlative Cell Culture Assays Guide In Vivo Imaging
Christopher H Contag
Molecular Imaging, 2003
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Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells
ed cable
Journal of Clinical Investigation, 1994
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Tin protoporphyrin induces intestinal chloride secretion by inducing light oxidation processes
Garry Buettner
AJP: Cell Physiology, 2006
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Effects of tin-protoporphyrin IX on blood flow in a rat tumor model
Gillian Tozer
Experimental biology and medicine (Maywood, N.J.), 2003
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The role of Bach1 in the induction of heme oxygenase by tin mesoporphyrin
Ronald Wong
Biochemical and Biophysical Research Communications, 2007
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Protoporphyrin IX: the good, the bad and the ugly
Karl Anderson
The Journal of pharmacology and experimental therapeutics, 2015
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Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: Evidence against a stress-mediated response
ed cable
Molecular and Cellular Biochemistry - MOL CELL BIOCHEM, 1997
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Heme oxygenase-1 inhibitor tin-protoporphyrin improves liver regeneration after partial hepatectomy
Monica Pibiri
Life Sciences, 2018
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Metalloporphyrins as Tools for Deciphering the Role of Heme Oxygenase in Renal Immune Injury
maria detsika
International Journal of Molecular Sciences
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Control of heme and cytochrome P-450 metabolism by inorganic metals, organometals and synthetic metalloporphyrins
George Drummond
Environmental Health Perspectives, 1984
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In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor
Jun Fang , Teruo Akuta
Cancer research, 2003
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Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha)
George Drummond
The Journal of experimental medicine, 1985
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Metalloporphyrins—Applications and clinical significance
tech perfect
Indian Journal of Clinical Biochemistry, 2000
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Photodynamic effects of hematoporphyrin-derivative on enzyme activities of murine …
Tom Dubbelman
… of Photochemistry and …
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Fluorimetric study of the binding of protoporphyrin to haemopexin and albumin
Angelo Lamola
Biochemical Journal, 1981
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