Active RNA polymerases are localized within discrete transcription “factories' in human nuclei (original) (raw)

Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III

Ana Pombo

The EMBO Journal, 1999

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Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei

Francisco Iborra

Molecular biology of the …, 1998

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Binding of the RNA polymerase I transcription complex to its promoter can modify positioning of downstream nucleosomes assembled in vitro

Philippe T Georgel

Journal of Biological Chemistry, 1993

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Localization of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry

U. Scheer

Proceedings of the National Academy of Sciences, 1984

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The transcription cycle of RNA polymerase II in living cells

PETER COOK

The Journal of Cell Biology, 2002

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Conditions Favoring RNA Polymerase I Transcription in Permeabilized Cells

Pascale Debey

Experimental Cell Research, 1996

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The proteomes of transcription factories containing RNA polymerases I, II or III

PETER COOK

Nature Methods, 2011

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Inhibition of RNA Polymerase II Transcription Causes Chromatin Decondensation, Loss of Nucleolar Structure, and Dispersion of Chromosomal Domains

David Ward

Experimental Cell Research, 1996

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RNA polymerase II transcription complex assembly in nuclear extracts

Chang Joong Kang

Gene expression, 1998

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The nucleolar architecture of polymerase I transcription and processing

Peter Shaw

The EMBO Journal, 1995

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Initiation of Nucleolar Assembly Is Independent of RNA Polymerase I Transcription

Chen Wang

Molecular Biology of the Cell, 2000

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The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors

Vincent Geli

Nucleic Acids Research, 2010

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Formation of transcribing mononucleosome-eukaryotic RNA polymerase II complexes in vitro as a simple model of active chromatin

Tatsuo Senshu

Nucleic Acids Research, 1984

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Transcription by Eukaryotic RNA Polymerases A and B of Chromatin Assembled in vitro

Bohdan Wasylyk

European Journal of Biochemistry, 1979

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Highly Restricted Localization of RNA Polymerase II within a Locus Control Region of a Tissue-Specific Chromatin Domain

Kirby Johnson

Molecular and Cellular Biology, 2003

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In vivo live imaging of RNA polymerase II transcription factories in primary cells

Wilfred van IJcken

Genes & Development, 2013

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Enzymatic fractionation of nuclei: Polynucleosomes and RNA polymerase II as endogenous transcriptional complexes

Jamshed Tata

Journal of Molecular Biology, 1978

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A Kinetic Framework for a Mammalian RNA Polymerase in Vivo

Ingrid Grummt

Science, 2002

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Two species of RNA polymerase II released from rat liver chromatin

Akira Inoue

FEBS Letters, 1979

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Sub-nuclear fractionation II. Intranuclear compartmentation of transcription in vivo and in vitro

Jamshed Tata

Experimental Cell Research, 1974

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Different populations of RNA polymerase II in living mammalian cells

Francisco Iborra

Chromosome …, 2005

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Transcribed DNA is preferentially located in the perichromatin region of mammalian cell nuclei

Karl-henning Kalland

Experimental Cell Research, 2011

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Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing

Arno Greenleaf

Genes & Development, 1993

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A RNA-dependent RNA polymerase activity: implications for chromatin transcription experiments

Bernd Groner

Nucleic Acids Research, 1977

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The Transcription Unit of Ribosomal Genes Is Attached to the Nuclear Skeleton

P. Hozák

Experimental Cell Research, 1996

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Loosely bound chromatin components are responsible for different electrophoretic mobility of the chromatin complexed with RNA polymerase II

Akira Inoue

FEBS Letters, 1980

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Eukaryotic ternary transcription complexes. I. The release of ternary transcription complexes of RNA polymerases I and II by the endogenous nucleases of rat liver nuclei

D. Sargan

Nucleic Acids Research, 1982

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Site of transcription of ribosomal RNA and intranucleolar structure in HeLa cells. J Cell Sci

Wilhelm Mosgoeller

Journal of Cell Science

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Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle

José Pérez-Ortín

Nucleic acids research, 2015

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Transcription factories are nuclear subcompartments that remain in the absence of transcription

Peter Fraser

Genes & Development, 2008

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The path that RNA takes from the nucleus to the cytoplasm: a trip with some surprises

Francisco Iborra

Histochemistry and cell biology, 2002

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Mammalian RNA polymerase I exists as a holoenzyme with associated basal transcription factors

Ingrid Grummt

Journal of Molecular Biology, 1998

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Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells

Ana Pombo, Sheila Xie

Experimental Cell Research, 2004

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Nucleosomes Can Form a Polar Barrier to Transcript Elongation by RNA Polymerase II

Yury Polikanov

Molecular Cell, 2006

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Effects of nucleosomes on transcription by polymerase I in a reconstituted system

Philippe T Georgel

1993

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