Perinatal Activation of Brown Adipose Tissue (original) (raw)

Springer eBooks, 1988

Abstract

Discussions concerning the significance of brown adipose tissue for the newborn mammal have become facilitated within the last few years by a general agreement on the following basic facts: That in all mammals, newborns as well as adults, facultative non-shivering thermogenesis is brown-fat thermogenesis That the molecular background to the unique ability of brown adipose tissue to function as a heat-producing organ is the existence in this tissue of a large abundance of mitochondria endowed with the uncoupling protein thermogenin, and That the amount of thermogenin in a mammal (under most circumstances) is the rate-limiting factor for thermogenesis.

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