Spontaneous and Controllable Activation of Suicide Gene Expression Driven by the Stress-InducibleGrp78Promoter Resulting in Eradication of Sizable Human Tumors
Khoi Nguyen Nguyen
Human Gene Therapy, 2004
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Stress Induction of GRP78/BiP and Its Role in Cancer
Amy Lee
Current Molecular Medicine, 2006
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GRP78 Induction in Cancer: Therapeutic and Prognostic Implications
Amy Lee
Cancer Research, 2007
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Expression of Stress Response Protein Grp78 Is Associated with the Development of Castration-Resistant Prostate Cancer
Richard Cote
Clinical Cancer Research, 2006
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GRP78 and Raf‐1 cooperatively confer resistance to endoplasmic reticulum stress‐induced apoptosis
Pei-Feng Liu
Journal of cellular …, 2008
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Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells
Britta Hardy, Rinat Yerushalmi, Annat Raiter
Oncotarget, 2014
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Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity
Michael Graner
2003
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Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands
Marco Arap, Alvaro Sarkis
Cancer Cell, 2004
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Secretion of stress protein grp170 promotes immune-mediated inhibition of murine prostate tumor
John Subjeck
Cancer Immunology, Immunotherapy, 2009
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Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity
Emmanuel Katsanis
Blood, 2001
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A new tumor-specific variant of GRP78 as target for antibody-based therapy
Stephanie Brandlein
Laboratory Investigation, 2008
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Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions
patricia fernandez
Breast cancer research …, 2000
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The critical role of GRP78 in physiologic and pathologic stress
Amy Lee
Current Opinion in Cell Biology, 2011
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Targeting GRP78 to enhance melanoma cell death
Shaun Martin
Pigment Cell & Melanoma Research, 2010
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Acute Inducible Ablation of GRP78 Reveals Its Role in Hematopoietic Stem Cell Survival, Lymphogenesis and Regulation of Stress Signaling
Amy Lee
PLoS ONE, 2012
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Accumulation of major stress protein 70kDa protects myeloid and lymphoid cells from death by apoptosis
Elena Lasunskaia
Apoptosis, 1997
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Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development
Dong Dong
Cancer Research, 2008
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The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress
Laurence Dubrez
2012
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GRP78 at the Centre of the Stage in Cancer and Neuroprotection
The Start
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Chaperoning Function of Stress Protein grp170, a Member of the hsp70 Superfamily, Is Responsible for its Immunoadjuvant Activity
John Subjeck, Masoud Manjili
Cancer Research, 2006
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Expression level of GRP78/BiP as a predictor of favorable or unfavorable outcomes in cancer patients
Rachid Benhida
Mediastinum
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Establishment of a chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94
Eva Liu
Journal of Cellular Physiology, 1992
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Differential effect of acute and permanent heat shock protein 70 overexpression in tumor cells on lysability by cytotoxic T lymphocytes
Ralf Dressel, Thomas Herrmann
Cancer research, 2003
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Heat Shock Protein 72 Modulates Pathways of Stress-induced Apoptosis
Robin Anderson
Journal of Biological Chemistry, 1998
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GRP94 reduces cell death in SH-SY5Y cells perturbated calcium homeostasis.
Alexéy N Alëshin
Apoptosis, Springer Nature, Kluwer Academic Publishers, 2004
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Cancer-inducible transgene expression by the Grp94 promoter: spontaneous activation in tumors of various origins and cancer-associated macrophages
Heather Kleiner
Cancer research, 2002
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Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9
zvi fishelson
Cell Death & Disease, 2018
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A stress‐inducible 72‐kDa heat‐shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells
Gabriele Multhoff
… journal of cancer, 1995
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Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells
saurabh vig
Cell Death & Disease, 2019
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Cellular stress responses: Cell survival and cell death
Afshin Samali
International Journal of Cell Biology, 2010
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