Optically active benzamides as predictive tools for mapping the dopamine D2 receptor (original) (raw)

Studies of the Active Conformation of a Novel Series of Benzamide Dopamine D2 Agonists

David Wustrow

Journal of Medicinal Chemistry, 1994

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Conformational Analysis of D1 Dopamine Receptor Agonists: Pharmacophore Assessment and Receptor Mapping

Val Watts

Journal of Medicinal Chemistry, 1996

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QSAR modeling on dopamine D2 receptor binding affinity of 6-methoxy benzamides

Tarun Jha

Il Farmaco, 2005

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Conformationally-flexible benzamide analogues as dopamine D 3 and σ 2 receptor ligands

Yunsheng Huang

Bioorganic & Medicinal Chemistry Letters, 2004

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Azaindole derivatives with high affinity for the dopamine D4 receptor: Synthesis, ligand binding studies and comparison of molecular electrostatic potential maps

Harald Hübner

Bioorganic & Medicinal Chemistry Letters, 1999

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A Density Functional Study of the Relationships between Electronic Structure and Dopamine D2 receptor binding affinity of a series of [4-(4-Carboxamidobutyl)]-1-arylpiperazines

Juan Sebastián Gómez-Jeria

Research Journal of Pharmaceutical, Biological and Chemical Sciences

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DOPAMINE D 2 RECEPTOR ANTAGONIST ACTIVITY AND MOLECULAR MODELING OF CERTAIN NEW CYCLOHEXANE DERIVED ARYLCARBOXAMIDES STRUCTURALLY RELATED TO METOCLOPRAMIDE

Aida El-Azzouny

Digest Journal of Nanomaterials and Biostructures

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Structure−Activity Relationships for a Novel Series of Dopamine D2-like Receptor Ligands Based on N-Substituted 3-Aryl-8-azabicyclo[3.2.1]octan-3-ol

Theresa Kopajtic

Journal of Medicinal Chemistry, 2008

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Potential antipsychotic agents. 9. Synthesis and stereoselective dopamine D-2 receptor blockade of a potent class of substituted (R)-N-[(1-benzyl-2-pyrrolidinyl)methyl]benzamides. Relations to other side chain congeners

Tomas de Paulis

Journal of Medicinal Chemistry, 1991

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Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

Ferran Sanz

Bioorganic & Medicinal Chemistry Letters, 2009

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Structural Factors that Distinguish Dopamine D1 and D2 Agonists

Emile Bellott

Journal of Molecular Modeling, 1995

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Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626

Robert Mach, Jinbin Xu

Bioorganic & Medicinal Chemistry, 2010

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Comparative Molecular Field Analysis of Dopamine D4 Receptor Antagonists Including 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5- a ]pyridine (FAUC 113), 3-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]-1 H -pyrrolo[2,3- b ]pyridine (L-745,870), and Clozapine

Peter Gmeiner

Journal of Medicinal Chemistry, 2001

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Further Definition of the D1 Dopamine Receptor Pharmacophore: Synthesis of trans-6,6a,7,8,9,13b-Hexahydro-5H-benzo[d]naphth[2,1-b]azepines as Rigid Analogues of β-Phenyldopamine

Val Watts

Journal of Medicinal Chemistry, 1997

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Structure−Activity Relationship Studies of 4-[2-(Diphenylmethoxy)ethyl]-1-benzylpiperidine Derivatives and Their N-Analogues: Evaluation of Behavioral Activity of O- and N-Analogues and Their Binding to Monoamine Transporters

aloke dutta

Journal of Medicinal Chemistry, 2001

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DOPAMINE D2 RECEPTOR ANTAGONIST ACTIVITY AND MOLECULAR MODELING OF CERTAIN NEW CYCLOHEXANE DERIVED ARYLCARBOXAMIDES …

Abdel-Sattar S. Hamad Elgazwy

chalcogen.ro

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Synthesis, 3D-QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

Ferran Sanz

ChemMedChem, 2010

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Synthesis, in silico, and in vitro studies of novel dopamine D 2 and D 3 receptor ligands

Holger Stark

Archiv der Pharmazie, 2021

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Synthesis, in silico, and in vitro studies of novel dopamine D2and D3receptor ligands

Katarina Nikolic

Archiv Der Pharmazie, 2021

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Certain 1,4-Disubstituted Aromatic Piperidines and Piperazines with Extreme Selectivity for the Dopamine D4 Receptor Interact with a Common Receptor Microdomain

Harel Weinstein

Molecular Pharmacology, 2004

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Investigation of key interactions between the second extracellular loop of dopamine D2 receptor and several hydroxy-N-{[2-(4-phenyl-piperaziny-1-yl)ethyl]phenyl}-nicotinamides

Đurđica Ignjatović

Journal of the Serbian Chemical Society, 2014

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Synthesis, dopamine D 2 receptor binding studies and docking analysis of 5-[3-(4-arylpiperazin-1-yl)propyl]-1 H-benzimidazole, 5-[2-(4-arylpiperazin-1-yl)ethoxy]-1 H-benzimidazole and their analogs

Goran Roglic

European Journal of Medicinal Chemistry, 2005

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Beyond small-molecule sar: Using the dopamine d3 receptor crystal structure to guide drug design

Thomas M. Keck

2014

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