Three-dimensional echocardiographic analysis of electromechanical synchrony: comparison with three-dimensional and two-dimensional ejection fraction for evaluation of left ventricular systolic performance (original) (raw)

Objective: To compare the three-dimensional echocardiographic analysis of left ventricular (LV) synchrony to LV ejection fraction (LVEF) as measured by two-dimensional (2D) and three-dimensional (3D) echocardiography (ECHO). Methods: This is a prospective study of 71 patients (41 males, aged 49 ± 11 years), 40 of whom with normal cardiac anatomy (ECHO) and electrocardiography (ECG) (Group N), and 31 with dilated cardiomyopathy (Group DCM). LVEF, volumes and 16-segment dyssynchrony index % (DI) were measured using 3D-ECHO. LVEF (Simpson's rule) and volumes were measured using 2D-ECHO. Data were compared using Pearson correlation coefficient (r), 95% CI, linear regression equation and Bland-Altman analysis, p < 0.05. results: DI% ranged from 0.32 to 21.7% (5.94 ± 6.46), 3D LVEF from 0.16 to 0.73 (0.51 ± 0.15); and 2D LVEF from 0.2 to 0.7 (0.47 ± 0.17). The correlation coefficient (r) for DI and 3D LVEF was (r):-0.8203, p < 0.0001, CI =-0.8844 to-0.7259, linear regression for DI% (x) and 3D LVEF (y) was y = 63.4515 + (-2.0233) x, p < 0.0001. The correlation coefficient (r) for DI% and 2D LVEF was (r):-0.7046, p < 0.0001, CI =-0.7675 to-0.5824, linear regression for DI% (x) and 2D EF (y) was y = 59.345 + (-3.8721) x, p < 0.0001. conclusions: Good negative correlation between LV synchrony (3D-ECHO) and echocardiographic LVEF (2D and 3D) was observed in this series.

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