Comparison of point-of-care glucometers and laboratory based glucose oxidase test in determining blood glucose levels (original) (raw)

The variability of results between point-of-care testing glucose meters and the central laboratory analyzer

Archives of pathology & laboratory medicine, 2006

Point-of-care testing glucose meters are strongly recommended in the management of diabetes and are increasingly being used for making therapeutically important decisions. Thus, it is essential that their results correlate well with those of laboratory analyzers. To test the reliability of point-of-care testing glucose meters. Two studies were performed: (1), an in-house study comparing accuracy of point-of-care testing glucose meters with a reference analyzer using fresh whole blood specimens (2), a real-time comparison of (a) 2 successive glucose meter readings and (b) glucose meter reading to central laboratory analyzer reading. (1), Seven glucose meters from 4 manufacturers were compared with the Yellow Springs YSI 2300 blood glucose analyzer using whole blood without preservative. (2), (a) Whole blood samples were read within 5 minutes of each other using Accu-Chek meters and (b) between a glucose meter and a Hitachi laboratory analyzer. (1) Within the Accu-Chek group of glucos...

Neonatal Blood Glucose Assessment (Glucometer Vs Serum

ALAZHAR UNIVERSITY, 2022

Background: One of the greatest prevalent metabolic problems in newborns is hypoglycemia. Neonatal hypoglycemia may be both symptomatic and asymptomatic. Hypoglycemia has been linked to cognitive impairment and neuromotor developmental delay. Aim of the study: The goal of the research was to discover the mean difference and correlation between capillary bedside glucose estimation by using glucometer in comparison venous sampling by using laboratory method. Patients and Methods: This cross-sectional comparative prospective research was undertaken on 200 newborns that were admitted to special care baby unit at Al-Wahda teaching Hospital-Derna, Libya from March 2018 till March 2019. Results: Agreement between blood sugar and glucometer blood sugar. Showing a significant agreement between venous blood sugar and glucometer blood sugar. Significant positive correlation between venous blood sugar and glucometer blood sugar. Conclusion: Given the significance of blood sugar levels in the identification of hypoglycemia in the early hours of life, glucometer readings must be reliable. Furthermore, these glucose meters need skin breaking, which causes discomfort and the risk of infection. However, there are presently no painless and non-invasive procedures for precisely determining glucose levels in newborns. There is a demand for the creation of such gadgets for valid reasons.

Challenges of implementing Point-of-Care Testing (POCT) glucose meters in a pediatric acute care setting

Clinical Biochemistry, 2004

Objectives: To investigate factors contributing to analytical bias in POCT glucose values generated by the NICU versus the core laboratory.Methods: The LifeScan Flexx hospital system glucose meters (SureStep) were used in precision and comparison studies between the NICU and laboratory (ABL715 and Vitros 950).Results: Analysis of 40 neonatal blood samples revealed a positive bias between the NICU glucose meters versus either the laboratory glucose meter or instrument (mean difference of 0.28 and 0.21 mmol/L, respectively). Linear regression analysis (R2 = 0.0584) of the difference in glucose results versus time elapsed between measurements indicated that the bias observed between the NICU and laboratory glucose meters was not due to in vitro glycolysis for samples transported on ice. Further analysis indicated that the bias appeared to be mostly operator driven, with different NICU operators exhibiting different mean biases. Increasing the amount of blood applied to the SureStep Pro test strip (e.g., 60 vs. 20 μL), led to higher values for glucose concentration for the same blood. Nearly 50% of all glucose values reported for the NICU were obtained by the SureStep Flexx glucose meters in a 3-month period following the introduction of POCT, yet the number of laboratory-reported glucose results for the same period increased by 21% as compared to the previous year.Conclusions: Operator error appears to be a source of bias present between the NICU and laboratory, and despite glucose meter utilization in the NICU, the number of glucose measurements by the central laboratory increased after POCT introduction.