Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells (original) (raw)

Oxidative DNA damage stalls the human mitochondrial replisome

Sjoerd Wanrooij

Scientific Reports, 2016

View PDFchevron_right

Persistent damage induces mitochondrial DNA degradation

Glenn Wilson

DNA Repair, 2013

View PDFchevron_right

Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis

S. Schaffer, Mikhail Alexeyev

AJP: Cell Physiology, 2007

View PDFchevron_right

Mitochondrial Regulation of Cell Cycle and Proliferation

Maria C Carreras

Antioxidants & Redox Signaling, 2012

View PDFchevron_right

Mitochondrial DNA Damage, Repair, Degradation and Experimental Approaches to Studying These Phenomena

Mikhail Alexeyev

intechopen.com

View PDFchevron_right

Mitochondrial DNA Damage: Role of Ogg1 and Aconitase

David Kamp

DNA Repair, 2011

View PDFchevron_right

Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress

Yau-Huei Wei

The international journal of biochemistry & cell biology, 2005

View PDFchevron_right

Mitochondrial Dysfunction Due to Oxidative Mitochondrial DNA Damage Is Reduced through Cooperative Actions of Diverse Proteins

Paul Doetsch

Molecular and Cellular Biology, 2002

View PDFchevron_right

Mitochondrial DNA Instability in Mammalian Cells

Isabela Mendes

Antioxidants & Redox Signaling, 2021

View PDFchevron_right

Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction

Bennett Van Houten

DNA Repair, 2012

View PDFchevron_right

Cell Sorting Experiments Link Persistent Mitochondrial DNA Damage with Loss of Mitochondrial Membrane Potential and Apoptotic Cell Death

Bennett Van Houten

Journal of Biological Chemistry, 2002

View PDFchevron_right

Formation and repair of oxidative damage in the mitochondrial DNA

Mateus Prates Mori

Mitochondrion, 2014

View PDFchevron_right

Mitochondrial DNA Damage and Diseases

U C Pachouri

F1000Research, 2015

View PDFchevron_right

The “fast” and the “slow” modes of mitochondrial DNA degradation

Mikhail Alexeyev

Mitochondrial DNA, 2014

View PDFchevron_right

Oxidative stress induces degradation of mitochondrial DNA

Inna Shokolenko

Nucleic Acids Research, 2009

View PDFchevron_right

Selective mitochondrial DNA degradation following double-strand breaks

Philippe Lachaume

PloS one, 2017

View PDFchevron_right

Increases in Mitochondrial DNA Content and 4977-bp Deletion upon ATM/Chk2 Checkpoint Activation in HeLa Cells

Feng Ling

PLoS ONE, 2012

View PDFchevron_right

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

Kunihiko Sakumi

The EMBO journal, 2008

View PDFchevron_right

Role of mitochondrial dysfunction in the pathophysiology of DNA repair disorders

Mateus Prates Mori

2018

View PDFchevron_right

Mitochondrial DNA damage induced autophagy, cell death, and disease

Joel Meyer

Frontiers in bioscience (Landmark edition), 2016

View PDFchevron_right

The maintenance of mitochondrial DNA integrity--critical analysis and update

Glenn Wilson

Cold Spring Harbor perspectives in biology, 2013

View PDFchevron_right

Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair

Michael Weinfeld

Nucleic Acids Research, 2012

View PDFchevron_right

The Pathophysiology of Mitochondrial Biogenesis: Towards Four Decades of Mitochondrial DNA Research

Rafael Garesse

Molecular Genetics and Metabolism, 2000

View PDFchevron_right

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA

Susana Gamen

1996

View PDFchevron_right

Mitochondrial control of apoptosis

Bernard Mignotte

Advances in Cell Aging and Gerontology, 2001

View PDFchevron_right

Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA

Magnar Bjørås

Mitochondrion, 2018

View PDFchevron_right

Mitochondrial fusion, fission, and mitochondrial toxicity

Joel Meyer

Toxicology, 2017

View PDFchevron_right

Mitochondrial nucleoid clusters protect newly synthesized mtDNA during Doxorubicin- and Ethidium Bromide-induced mitochondrial stress

Martin Jabůrek

Toxicology and Applied Pharmacology, 2016

View PDFchevron_right

Mitoptosis: Different Pathways for Mitochondrial Execution

Maurizio Sorice

Autophagy, 2007

View PDFchevron_right

DNA repair in mammalian mitochondria: Much more than we thought?

Bruce Demple

Environmental and Molecular Mutagenesis, 2010

View PDFchevron_right

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress

Aditi Chatterjee

BMC cancer, 2006

View PDFchevron_right

Oxidative Stress and Upregulation of Mitochondrial Biogenesis Genes in Mitochondrial DNA-Depleted HeLa Cells

Javier Guerrero

Biochemical and Biophysical Research Communications, 1999

View PDFchevron_right

Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

Yau-huei Wei

Biochemical Journal, 2000

View PDFchevron_right

Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes

Sanduni Liyanage

Nature Chemical Biology, 2016

View PDFchevron_right

Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus

keshav singh

Mutagenesis, 2003

View PDFchevron_right