Recent Trends In The Management of Cystic Fibrosis: A Review (original) (raw)

Cystic fibrosis (CF) is an inherited disease of secretory glands. Cystic fibrosis mostly affects the lungs, pancreas, liver, intestines, sinuses, and sex organs. It doesn't affect the brain. A defect in the CFTR gene causes cystic fibrosis. This gene makes a protein that controls the movement of salt and water in and out of body's cells. Every person inherits two CFTR genes. One from each parent. Children who inherit a faulty gene from each parent will have cystic fibrosis. Diagnosis of cystic fibrosis is based on the results from various tests newborn screening, sweat test, prenatal screening, cystic fibrosis carrier testing and other tests. Cystic fibrosis treatments have greatly improved in recent years. Treatments are based on various body part. In treatment of cystic fibrosis chest physical therapy, exercise therapy and medicines are used & mostly antiinflammatives, antibiotics, antihistamines, mucolytics, vitamins, GI drugs, stool softeners, bronchodilators, pancreatic enzymes and nasal sprays are used. Oxygen therapy and lung transplant are the advance treatments for lung diseases. As new treatments are developed for patients with CF, efforts should be made to balance treatment burden with quality of life. This review highlights emerging treatments, obstacles to optimizing outcomes, and key future direction for research.