Partial sternectomy with reconstruction of a giant cell tumor of the sternum, a case report, Saudi, Arabia (original) (raw)

Primary malignant giant cell tumor of the sternum

Autopsy Case Reports, 2021

Primary malignant giant cell tumor (PMGCT) is a diagnosis based on the presence of a high-grade sarcomatous component along with a typical benign giant cell tumor (GCT). We report the first case of PMGCT of the sternum in a 28-year-old male with painless swelling over the manubrium sterni. The differential diagnoses of PMGCT and giant cell-rich osteosarcoma were considered. Surgical resection was performed, and the reconstruction was done with a neosternum using polymethyl methacrylate and prolene mesh. At 30 months follow-up, the patient is disease-free.

Anterior chest wall giant cell tumor

General thoracic and …, 2010

Giant cell tumors (GCTs) of bone are rare primary neoplasms that usually originate from the epiphysis of long bones. Even when the tumor occurs in a rib, it is usually in the posterior aspect. We report a case of a GCT originating from the anterior arc of the rib in a 22-year-old woman presenting with a progressively growing thoracic mass in the right anterior chest wall. Through this case the authors emphasize not only the rarity of a bone GCT but also its unusual costal localization.

Clinical, radiological and pathological correlation of giant cell tumor of rib

2015

Giant cell tumor (GCT) is a primary benign neoplasm of bone accounting for 5% of all skeletal tumors. Although considered benign, it has propensity for local recurrence, distant metastasis as well as malignant transformation. GCTs of bone usually arise in the epiphyseal region of the limbs, and rarely it affects the ribs. We report a case 52-year-old male who presented with left sided rib mass. Total excision of rib mass with thoracic reconstruction with prolene mesh was done. Microscopic examination of the mass showed features of giant cell tumor. Authors consider the rarity location of this entity along with unusual clinical presentation worth to publish.

Unusual Presentation of a Rare Chest Wall Tumor: Giant Cell Tumor of Bone

International Journal of Medicine and Surgery, 2019

Introduction: Giant cell tumours account 5% of all bone tumours. However, the anterior chest wall is rarely involved . Clinical case: This is a 68-year-old housewife who has been thyroidectomized, for 11 years and is under hormone replacement therapy, and hysterectomized for 6 years after a uterine tumor. She is present for the onset of a 5 month old hard submammary mass on the left associated with left anterior chest pain under mammals. The clinical examination had found an irregular hard mass under left mammary which is fixed to the anterior arch of the 4th left rib. A thoracic x-ray showed a limited left hilo-axillary with an homogenously dense opacity. The thoracic CT scan showed the presence of a thoracic parietal mass of osteolytic tissue density centered on the anterior arch of the 4th left rib; without contrast agent, the surgical exploration through thoracotomy revealed a thoracic parietal tumoral process at the expense of the anterior arch of the 4th limb pushing the corre...

Surgical treatment for giant cell tumor of the thoracolumbar spine

Chang Gung medical journal

Giant cell tumor (GCT) of the bone has historically been regarded as an extremely unpredictable bone tumor. The anatomical characteristics of spinal GCT still present challenges to surgeons. Controversy remains regarding the proper treatment of patients with grade III tumors. Eleven patients with grade III GCT of the thoracolumbar spine were treated between 1992 and 2002 at a medical center by the authors. Three patients were initially treated at other institutions. Adjuvant radiotherapy was employed for local recurrence in these three patients. The other eight patients were initially treated with marginal excision. The site, size, and extent of each lesion dictated the surgical approach. Five patients had tumor recurrence. One patient, who received radiotherapy, had local relapse with malignant transformation and finally died due to disease-related complications. One patient had a recurrent tumor with multiple metastases throughout the lung. Neurological status, measured using the ...

Malignant Sternal Tumors: Report of Two Cases

Nepalese Journal of Cancer

Primary malignant sternal tumors are rare clinical entities. We came across two such patients with primary sternal tumors. One was a chondroblastic osteosarcoma while the other was a chondrosarcoma. One patient received neoadjuvant chemotherapy followed by surgery. The second patient underwent upfront surgery. Both cases received wide excision of the tumor (sternum along with part of medial ends of bilateral clavicles and upper ribs). Reconstruction was done using autologous bone graft with prolene mesh in one case and titanium reconstruction plates in the other case. Both cases received coverage with pectoralis major muscle flaps.

Giant Cell Tumor of the Ribs: A Case Report

2021

Background: Giant Cell Tumor (GCT) is a benign tumor but can be malignant and spread to other organs. Common site of GCT develops in long bone, especially in the knee. A lesion that develops in flat bone is considered rare. This case report aims to recognize GCT of bone and its predilection and help improve diagnostics and manage this case to provide better results. Case Report: A seven-year-old female came with complaints of lump and intermittent pain in left-back. The lump is gradually getting more prominent. The pain is localized in the back mid-area, worsen with any touch around the area. On examination, there is deformity and mass on the posterolateral side at the 9th rib level around 3 cm in diameter. There was tenderness on palpation and limited range of motion (ROM). The cytological and radiological finding suggests GCT of bone. The patient had resection surgery of the lesion. The histopathologic results on the operative specimens confirmed the diagnosis of GCT. Discussion: ...