Psoriatic disease treatment nowadays: unmet needs among the “jungle of biologic drugs and small molecules” (original) (raw)

Rheumatology has made significant advances in understanding and treating psoriatic disease (PsD), shifting the perception of psoriasis from a cosmetic concern to a systemic disease linked to increased cardiovascular risks and obesity. The integration of biologic drugs targeting key inflammatory cytokines has transformed management strategies. Despite the growing number of treatments, challenges remain in predicting side effects, establishing guidelines for therapy selection, and addressing the complex clinical presentations of PsD; thus, further research into precision medicine and pharmacogenomics is essential for optimizing patient-centered care.