Pathogenicity of Aeromonas hydrophila in High-value Native Pangasius Catfish, Pangasius nasutus (Bleeker (original) (raw)

Pangasius catfish, Pangasius nasutus, is a promising candidate for aquaculture due to its high market value. However, the presence of pathogenic bacteria in Aeromonas hydrophila is a major concern in P. nasutus farming in this country. This study determines the pathogenicity of A. hydrophila in P. nasutus. A total of 80 P. nasutus juveniles were intraperitoneally injected with 0, 10 3 , 10 5 , and 10 7 CFU mL-1 of A. hydrophila and monitored until 240 hr. The infected moribund fish's kidneys, livers, and spleens were collected for histopathological analysis. The LD 50-240hr value was found at 0.8 × 10 4 CFU/ml of A. hydrophila. The percentage of mortality in 0, 10 3 , 10 5 , and 10 7 CFU/ml infected groups were found to be at 0, 40, 60, and 90%, respectively. The infected fish showed congestion at the base of the fin, ascites, enlarged gall bladder, and swollen spleen. It is the earliest report on A. hydrophila's pathogenicity in high-value native fish, P. nasutus.