COVID-19 with Pregnancy: Obstetricians should be Alert for Postpartum Exacerbation (original) (raw)
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Impact of COVID-19 on pregnancy and delivery — current knowledge
Ginekologia Polska
The World Health Organization announced on 12 March 2020 a global pandemic of the new SARS-CoV-2 coronavirus causing COVID-19 disease associated with pneumonia and acute respiratory failure. SARS-CoV-2 has caused so far over 6.66 million recorded cases, of which 393,000 ended in death (as of June 1, 2020). Despite the demographic statistics of incidence, there is no current recording of cases in the group of pregnant or perinatal women. Changes occurring in the female body system during pregnancy also affect and alter the immune system, and as studies based on other viral respiratory infections have shown, the population of pregnant women is at risk of having a severe course of the disease. The aim of the study is to summarize current reports on the course of COVID-19 disease in a group of pregnant women and the possible impact of SARS-CoV-2 on the foetus and vertical transmission, taking into account changes occurring in the woman's immune system during pregnancy. Available advice and recommendations for antenatal and perinatal care of pregnant women during the pandemic period are also included.
Impact of COVID-19 on Pregnancy and Maternal Health: An Update
Biomedical Research and Therapy, 2021
The current pandemic caused by the novel coronavirus disease 2019 (COVID-19) is spreading at an accelerated rate globally. Global concerns were raised following its discovery in December 2019, as previous similar diseases. Diseases such as the severe acute respiratory syndrome-related coronavirus (SARS-CoV) and the Middle East respiratory syndrome-related coronavirus (MERS-CoV) are known to lead to adverse outcomes in pregnant women and those in early maternal stages, with significantly higher rates of complication and mortality compared to other groups of individuals. The anatomical, physiological, and immunological changes that occur during pregnancy lead to higher risks associated with respiratory infections for pregnant women, as they can directly affect the well-being of pregnant women and infants. Vertical transmission of COVID-19 from mother to child was a concern, as such transmission could endanger a child. Three mechanisms of vertical transmission have been suggested: intrauterine transmission, placental blood transmission, and intrapartum transmission. This review discusses the impact and pathogenicity of COVID-19 on the well-being of pregnant and early maternal women, both the clinical aspect, health aspects, and diagnostic and therapeutic options. It will also discuss the adverse outcomes among pregnant women and newborn infants who contract the disease and the different mechanisms of vertical transmission from infected mother to child. The diagnostic and therapeutic approaches of COVID-19 that have been recently used have also been highlighted, in addition to the challenges faced by pregnant women who have contracted the virus during the pandemic.
Pregnancy Covid 19 infection: Our experience
Indian Journal of Obstetrics and Gynecology Research, 2021
Corona virus disease also known as Covid -19 pandemic has represented major impact to health system and societies world-wide. There is no particular high risk seen among mother and fetus. In addition to these aspects specifically to Covid -19 and gestation that should be known by specialist in order to correctly diagnose disease, classify severity, distinguish obstetric complications with specific signs of Covid -19 and for taking most appropriate management decision. The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has exposed vulnerable populations to global health crisis. Mother and fetuses are particularly susceptible to poor outcome. There are very limited data how SARS‐CoV‐2 behaves in pregnant women & their infants. We pearly reviewed 52 gravida infected with covid-19 pneumonia. Out of which 25 symptomatic patients admitted to our hospital while 27 asymptomatic but Covid positive patients care taken on OPD basis followed by home quaranti...
Rev. peru. ginecol. obstet. (En línea), 2020
Objective: To search for all the information and available evidence on infection with SARS-CoV-2, a virus that appeared during the first 4 months of 2020, and pregnancy. Methods: Systematic review in PubMed and Google Scholar databases until April 25, 2020. We searched for published articles related to pregnant women infected with SARS-CoV-2. There was no language restriction. The search was extended to the references of the articles found. Results: In pregnant women with COVID-19, more than 90% of patients evolve mildly, 2% require intensive care. One maternal death has been reported. Prematurity occurs in approximately 25% of the cases, with predominance of late preterm infants; premature rupture of membranes presents in about 9%. Perinatal mortality is lower or similar to that of the general population, and vertical transmission has not been shown. Conclusions: Obstetrician-gynecologists must prepare to attend more cases with COVID-19 and therefore they need to know this disease. COVID-19 progresses similarly in pregnant and non-pregnant women, although it is associated to prematurity. While vertical transmission has not been demonstrated, horizontal transmission during vaginal birth is very likely.
Frontiers in Global Women's Health, 2021
The new coronavirus (SARS-Cov-2) was first identified in late 2019 as the new RNA virus in the coronaviridae family responsible for causing COVID-19 in the residents of China's Hubei province. In mid-March 2020 WHO declared the pandemic caused by this virus as a result of thousands of people infected all over the world. Epidemiological evidence obtained from other pandemics, such as influenza and ebola, suggest that pregnant women are more susceptible to serious complications and death from viral infection. Physiological changes in the anatomical structure of the respiratory system as well as in the immune system during the pregnancy-puerperal period seem to contribute to this greater risk. Thus, pregnant women are more susceptible to be infected by the SARS-COV-2 or other viruses and to have serious COVID-19 disease. In fact, COVID-19 can alter immune responses at the maternal-fetal interface, affecting the well-being of both mother and her fetus. There is still no sufficient e...
Pregnancy and Covid-19: A Literature Review
Proceedings of the International Conference of Health Development. Covid-19 and the Role of Healthcare Workers in the Industrial Era (ICHD 2020), 2020
Background: Coronavirus is a large family of viruses that can cause disease from mild to severe symptoms. COVID-19 attacks people of all ages including vulnerable groups such as pregnant women. Numbers of previous researches on the coronavirus, (SARS-CoV and MERS-CoV), stated that pregnant women have a higher risk of severe disease, morbidity, and mortality compared to the general population. However, there are only a few studies on COVID-19's relationship with pregnancy and childbirth. Methods: This research used a literature review method. Sources of literature data were obtained from PubMed, Ebsco and Proquest taken from 2019-2020. Results: The results of the research based on 7 articles. The results showed that there was no difference in the signs and symptoms experienced by pregnant women with Covid-19 infection when compared to the general population. Until today, a number of studies have been conducted to determine the vertical transmission of COVID-19 from mother to fetus. Conclusions: A number of samples such as umbilical cord blood, amniotic fluid, neonatal throat swab, breast milk, and vaginal secretions were taken for examination and showed negative results. Maternal-fetal transmission of COVID-19 was undetected in the majority of reported cases. Yet, careful pregnancy monitoring with COVID-19 and steps to prevent neonatal infection is still needed. Mothers who are infected are at a higher risk of having severe respiratory complications.
ABSTRACTObjectiveThe aim of this systematic review was to examine the maternal and fetal outcomes in pregnant women with COVID-19 and also assess the incidence of maternal-fetal transmission of SARS CO-V-2 infection.Data sourcesWe searched PUMBED. Medline, Embase, MedRxiv and bioRxiv databases upto 3rd May 2020 utilizing combinations of word variants for “coronavirus” or “COVID-19” or “severe acute respiratory syndrome” or “SARS-COV-2” and “pregnancy”. We also included data from preprint articles.Study eligibility criteriaOriginal case reports and case series on pregnant women with diagnosis of SARS-CoV-2 infection.Study appraisal and synthesis methodsWe included 50 studies reporting the information on 441 pregnant women and 391 neonates. The primary outcome measures were maternal health characteristics and adverse pregnancy outcomes, neonatal outcomes and SARS-CoV-2 infection in neonates was extracted. Treatments given to pregnant women with COVID-19 were also recorded.ResultsOut o...
Risks of Novel Coronavirus Disease (COVID-19) in Pregnancy; a Narrative Review
Archives of Academic Emergency Medicine, 2020
Introduction: The outbreak of the new Coronavirus in China in December 2019 and subsequently in various countries around the world has raised concerns about the possibility of vertical transmission of the virus from mother to fetus. The present study aimed to review published literature in this regard. Methods: In this narrative review, were searched for all articles published in various databases including PubMed, Scopus, Embase, Science Direct, and Web of Science using MeSH-compliant keywords including COVID-19, Pregnancy, Vertical transmission, Coronavirus 2019, SARS-CoV-2 and 2019-nCoV from December 2019 to March 18, 2020 and reviewed them. All type of articles published about COVID-19 and vertical transmission in pregnancy were included. Results: A review of 13 final articles published in this area revealed that COVID-19 can cause fetal distress, miscarriage, respiratory distress and preterm delivery in pregnant women but does not infect newborns. There has been no report of ve...
Pregnancy and Childbirth During COVID-19 Pandemic: A Case Series and Review of Literature
Original Article, 2021
Introduction: In March 2020, the World Health Organization introduced the Coronavirus disease 2019 (COVID-19) pandemic as a global health concern and predicted that without any changes in the transmission process, the disease would reach its peak in April. Hence, it was not unreasonable to expect the referral of pregnant women in all trimesters. Since respiratory illnesses can increase the risk of infectious diseases and maternal mortality, it is justifiable to consider COVID-19-positive cases as high-risk pregnancies. Case presentation: The present study introduced six pregnant women with COVID-19 and discussed the points to consider in managing these patients. Conclusions: Pregnant women are at increased risk in all epidemics of infectious diseases due to their physiological and immunological changes. Moreover, the safety of the fetus is another important issue to consider.