Enhanced Tumor Uptake of Macromolecules Induced by a Novel Vasoactive Interleukin 2 Imrnunoconjugate1 (original) (raw)

Identification of a monoclonal antibody, TV-1, directed against the basement membrane of tumor vessels, and its use to enhance the delivery of macromolecules to tumors after conjugation with interleukin 2

Clive Taylor

Cancer research, 1995

View PDFchevron_right

Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules

Paolo A Netti

Proceedings of the National Academy of Sciences of the United States of America, 1999

View PDFchevron_right

Systemic perfusion: a method of enhancing relative tumor uptake of radiolabeled monoclonal antibodies

Onelio Geatti

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1988

View PDFchevron_right

Effect of increasing vascular hydraulic conductivity on delivery of macromolecular drugs to tumor cells

Timothy Secomb

International Journal of Radiation Oncology*Biology*Physics, 1995

View PDFchevron_right

Influence of vasoactive drugs on local tumor blood flow

Jan Mattsson

European Journal of Cancer and Clinical Oncology, 1982

View PDFchevron_right

Modification of tumor blood flow: Current status and future directions

Gillian Tozer

Seminars in Radiation Oncology, 1998

View PDFchevron_right

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

Napoleone Ferrara

Proceedings of the National Academy of Sciences, 1996

View PDFchevron_right

Quantitative and qualitative effects of experimental radioimmunotherapy on tumor vascular permeability

R. Kashi

International Journal of Cancer, 1995

View PDFchevron_right

Use of Antibody as Carrier of Oligomers of Peptidomimetic α v β 3 Antagonist to Target Tumor-Induced Neovasculature

King Li

Bioconjugate Chemistry, 2007

View PDFchevron_right

Effect of Inhibition of Vascular Endothelial Growth Factor Signaling on Distribution of Extravasated Antibodies in Tumors

D. Hu-Lowe

Cancer Research, 2006

View PDFchevron_right

Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors

T. Shockley

Cancer research, 1992

View PDFchevron_right

Identification of a Monoclonal Antibody, TV1, Directed against the Basement Membrane of Tumor Vessels, and Its Use to Enhance the Delivery of Macromolecules to Tumors after Conjugation with Interleukin 21

Clive Taylor, Jason Hornick

2000

View PDFchevron_right

Bevacizumab-Induced Vessel Normalization Hampers Tumor Uptake of Antibodies--Response

Sjoukje Oosting

Cancer Research, 2013

View PDFchevron_right

Effect of VEGF receptor-2 antibody on vascular function and oxygenation in spontaneous and transplanted tumors

Bruce Fenton

Radiotherapy and Oncology, 2004

View PDFchevron_right

Vascular Permeability and Drug Delivery in Cancers

jagoda hebda

Frontiers in Oncology, 2013

View PDFchevron_right

Blood flow and Vd (water): both biomarkers required for interpreting the effects of vascular targeting agents on tumor and normal tissue

Terry Jones

Molecular Cancer Therapeutics, 2009

View PDFchevron_right

The mechanistic immunosuppressive role of the tumour vasculature and potential nanoparticle-mediated therapeutic strategies

Jale Yuzugulen

Frontiers in Immunology

View PDFchevron_right

Short-period-induced hypertension could improve tumor-to-nontumor ratios of radiolabeled monoclonal antibody

Takatoshi Michigishi

Nuclear Medicine and Biology, 1997

View PDFchevron_right

Selective occlusion of tumor blood vessels by targeted delivery of an antibody-photosensitizer conjugate

Luciano Zardi

International Journal of Cancer, 2006

View PDFchevron_right

Antibody drug-conjugates targeting the tumor vasculature: Current and future developments

Hans-peter Gerber

mAbs

View PDFchevron_right

Antitumor Effects of a Monoclonal Antibody that Binds Anionic Phospholipids on the Surface of Tumor Blood Vessels in Mice

Douglas Scothorn

Clinical Cancer Research, 2005

View PDFchevron_right

Tumor blood vessels, a difficult hurdle for infiltrating leukocytes

Arjan Griffioen

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2007

View PDFchevron_right

High Interstitial Fluid Pressure Is Associated with Low Tumour Penetration of Diagnostic Monoclonal Antibodies Applied for Molecular Imaging Purposes

Markus Heine

PLoS ONE, 2012

View PDFchevron_right

Kinetics of Radioiodinated Monoclonal antibodies in the Rat: Influence of Tumour Growth and Reticuloendothelial System Host Modulation

Lars Jacobsson

Acta Oncologica, 1989

View PDFchevron_right

Thrombospondin 1 and vasoactive agents indirectly alter tumor blood flow

Lisa Ridnour

Neoplasia, 2008

View PDFchevron_right

The use of bispecific antibodies in tumor cell and tumor vasculature directed immunotherapy

Wijnand Helfrich

Journal of Controlled Release, 2000

View PDFchevron_right

Pretreatment with a monoclonal antibody/interleukin-2 fusion protein directed against DNA enhances the delivery of therapeutic molecules to solid tumors

Peisheng Hu

Clinical cancer research : an official journal of the American Association for Cancer Research, 1999

View PDFchevron_right

A general extracorporeal immunoadsorption method to increase tumor-to-tissue ratio

Sven-erik Strand

Cancer, 1994

View PDFchevron_right

Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes

Matteo Bellone

Frontiers in oncology, 2013

View PDFchevron_right

Won’t you come on in? How to favor lymphocyte infiltration in tumors

Matteo Bellone

OncoImmunology, 2012

View PDFchevron_right

Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers

David Needham

JNCI Journal of the National Cancer Institute, 2006

View PDFchevron_right