Pattern and antimicrobial susceptibility of organisms causing blood stream infection in a Neonatal Intensive Care Unit (NICU) from India (original) (raw)

2017

Abstract

Background: Globally infections are the single most common cause of neonatal deaths. A report from India (National Neonatal-Perinatal Database - NNPD: 2002-03) showed incidence of sepsis was 30/1000 live births (LB). Pattern and antimicrobial susceptibility of organisms have kept on changing in the NICU. Objective: To identify common bacterial pathogens associated with neonatal sepsis in a tertiary care NICU and to determine their antibiotic susceptibility pattern. Design/Methods: Prospective descriptive study. Blood culture reports of culture positive neonatal sepsis admitted to Level III NICU in South India during January 2011-June 2012 were analyzed. Demographic data of the babies was collected. Results: Total 1924 blood cultures were done for in total 1924 blood cultures were done for babies with suspected clinical sepsis. The yield rate was 9.3% (n=179/1924). The incidence of culture proven sepsis was 24/1000 live births. Of all, 82% (n=148) were Gram-negative organism, 11% (n=...

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