The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis (original) (raw)

Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors

Frans Klis

Biochimica et Biophysica Acta (BBA) - General Subjects, 1995

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Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria

Philip Mason

Proceedings of the National Academy of Sciences, 1993

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Hypomorphic Promoter Mutation In PIGM Causes Inherited Glycosylphosphatidylinositol Deficiency

Antonio Almeida

Nature medicine, 2006

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Clinical variability in inherited glycosylphosphatidylinositol deficiency disorders

Philippe Campeau

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Mutations in PIGY: expanding the phenotype of inherited glycosylphosphatidylinositol (GPI) deficiencies

Taroh Kinoshita

Human molecular genetics, 2015

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Glycosyl phosphatidylinositol (GPI)-anchored molecules and the pathogenesis of paroxysmal nocturnal hemoglobinuria

Asit Pattnaik

Critical Reviews in Oncology/Hematology, 2000

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Ethanolamine phosphate on the second mannose as bridge in GPI anchored proteins: Towards understanding inherited PIGG deficiency

Philippe Campeau

2020

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The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria

Robert Brodsky

The American Journal of Human Genetics

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Congenital disorder of glycosylphosphatidylinositol (GPI)-anchor biosynthesis—The phenotype of two patients with novel mutations in the PIGN and PGAP2 genes

Rafał Płoski

European Journal of Paediatric Neurology, 2016

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Deletion of GPI7, a Yeast Gene Required for Addition of a Side Chain to the Glycosylphosphatidylinositol (GPI) Core Structure, Affects GPI Protein Transport, Remodeling, and Cell Wall Integrity

Abdellah Benachour

Journal of Biological Chemistry, 1999

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Restrictive Glycosylphosphatidylinositol Anchor Synthesis incwh6/gpi3 Yeast Cells Causes Aberrant Biogenesis of Cell Wall Proteins

Wally Muller

1997

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Analysis of the sequence requirements for glycosylphosphatidylinositol anchoring of Saccharomyces cerevisiae Gas1 protein

Anton Horváth

Journal of Biological Chemistry, 1993

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Glycosylphosphatidylinositol (GPI)-deficient Jurkat T cells as a model to study functions of GPI-anchored proteins

M. Deckert

Clinical and Experimental Immunology, 2000

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Identification of ω-sites of Glycosylphosphatidylinositol Anchored Proteins

sciaccess inc

Journal of Immunological Sciences, 2018

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GWT1 Gene Is Required for Inositol Acylation of Glycosylphosphatidylinositol Anchors in Yeast

michiyo okamoto

Journal of Biological Chemistry, 2003

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Different Roles of Glycosylphosphatidylinositol in Various Hematopoietic Cells as Revealed by a Mouse Model of Paroxysmal Nocturnal Hemoglobinuria

Taroh Kinoshita

Blood, 1999

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The cell cycle modulated glycoprotein GP115 is one of the major yeast proteins containing glycosylphosphatidylinositol

Lilia Alberghina, Marina Vai

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990

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Targeted Therapy for Inherited GPI Deficiency

Taroh Kinoshita

New England Journal of Medicine, 2007

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A screen for deficiencies in GPI-anchorage of wall glycoproteins in yeast

Marlyn Gonzalez, Charles Hicks

Yeast, 2010

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PIG-W Is Critical for Inositol Acylation but Not for Flipping of Glycosylphosphatidylinositol-Anchor

Taroh Kinoshita

Molecular Biology of the Cell, 2003

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GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the 1,4-linked mannose of the complete precursor glycophospholipid

Abdellah Benachour

Glycobiology, 1998

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Inherited glycosylphosphatidyl inositol deficiency: a treatable CDG

Antonio Almeida

Biochimica et biophysica acta, 2009

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GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the α1,4-linked mannose of the complete precursor glycophospholipid

Abdellah Benachour

Glycobiology, 1998

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PIG-V Involved in Transferring the Second Mannose in Glycosylphosphatidylinositol

Taroh Kinoshita

Journal of Biological Chemistry, 2004

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Isolation and deduced amino acid sequence of the gene encoding gp115, a yeast glycophospholipid-anchored protein containing a serine-rich region

Marina Vai

Journal of Biological Chemistry

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