Immunoprophylaxis of an Ocular Solid Malignant Tumor in Cattle234 (original) (raw)

JNCI: Journal of the National Cancer Institute, 1983

Abstract

Individual Hereford cows bearing benign precursor lesions of ocular squamous cell carcinoma were treated by intralesional injection of mycobacterial cell walls in an oil-in-water emulsion in an attempt to interrupt neoplastic progression. Thirty-one months after treatment, statistical analysis of data indicated that intralesional BCG cell wall vaccine can interrupt this process and provides effective immunoprophylactic prevention of malignant disease.

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