AN APPRAISAL ON ETHNO-MEDICINAL CLAIMS OF CALOTROPIS PROCERA AIT AND CALOTROPIS GIGANTEA (LINN) R.BR. - TWO SOURCE DRUGS OF AYURVEDIC MEDICINAL PLANT ‘ARKA’ (original) (raw)

Calotropis procera (Arka): A Tribal Herb of Utmost Significance

2021

Nature has gifted humans a vast variety of medicinal plants, which are the rich source of bioactive compounds. Calotropis procera is an important medicinal plant that belongs to the family asclepiadaceae. It is commonly known as madar and milkweed plant in english and arka in hindi. It is mostly found in the tropics of asia and africa. Calotropis procera is a highly valued plant in the folk medication system. Each part of the plant is richly endowed with diverse nature of phytochemical constituents like alkaloids, proteins, vitamins, carbohydrates, saponins, terpenes, and flavonoids, etc. These phytochemicals are significantly associated with various therapeutic and pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory, anti-ulcer, antifertility, anti-diarrheal, and spasmolytic. In this review article, the therapeutic and pharmacological value of this important plant has been summarized along with its utilization in the folklore and ayurvedic medicinal s...

A Review on Biological Activities of Indian Traditional Medicinal Plant: Calotropis Gigantea

Journal of Biomedical and Allied Research, 2022

India, which is aptly referred to as the world's botanical garden, is the country that produces the most medicinal herbs. The Apocynaceae/Asclepiadaceae family member, Calotropis gigantea sometimes known as the Crown Flower, has special therapeutic characteristics that can be used on its own or in combination with other drugs to treat common illnesses. There is a surprising therapeutic diversity in herbal medications. Entire dried plant is employed as rejuvenating, parasitic worm expellers and mucus explusors in ayurveda. While latex of it cures vertigo, baldness, hair loss, and rheumatoid arthritis, and to treat asthma root in dry form is used, leprosy. Calotropis is employed as a homoeopathic remedy in addition to its conventional purposes. Significant medicinal benefits can be obtained from the plant's extracts from its many components. It is necessary to objectively investigate these treatments in order to determine their active principles and comprehend their pharmacological properties, such as prophylactic protective, NSAID, antibacterial, antimicrobial, anti-oxidant, antiulcer ,helps in treating Covid-19, antimalarial, antipyretic, wound healing activity, cytotoxic properties, anti-asthmatic , procoagulant , CNS and anticonvulsant activity, pregnancy interceptive, anticancer, analgesic, antidiabetic, antidiarrheal, insecticidal, and hepatoprotective. It provides data about the mythical importance, herbal relevance, origin, pharmacogenetic illustration, herbal constituents, biological activities, and ethnopharmacological noteworthiness of Calotropis gigantea is summarized in the current review.

STUDIES ON THE METHOD–ETHNOBOTANY OF CALOTROPIS GIGANTEA AND C. PROCERA

Ancient science of life, 1993

The paper reviews the economic and traditional medicinal uses of the plants, Calotropis gigantean and C. procera from the published literature from various of India. The ethno-medicinal uses of the former species in Orissa are also incorporated. Their distribution in India, Botany, Physical and Chemical properties of the plant parts are provided. Uses of the traditional medicines and their authentication as evidence by the available clinical trials are discussed. Besides, uses and standardization of doses against various ailments are suggested.

PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF LEAVES OF CALOTROPIS GIGANTEA.

International Journal of Advanced Research (IJAR), 2019

Arka (Calotropisgigantea) an important drug of Ayurveda is known in this country from the earliest time. It is commonly known as giant milk weed. It is used for several medication purposes in traditional medicinal system. Most recently Calotropisgiganteais scientifically reported for several medicinal properties viz. the flowers were reported to possess analgesic activity, antimicrobial and cytotoxic activity. Leaves and Arial parts of the plant were reported for anti-diarrhoeal activity, antibacterial activity, antioxidant activity. Roots were reported to contain anti-pyretic activity, cytotoxic activity. The present study is an effort to give detail information regarding macroscopy, microscopy, physical constants, leaf constants, fluorescence analysis and phytochemical screening of leaves extracts of Calotropisgigantea. This study helps in identification of this particular plant species. Also it providesguidelines for identification of plant species.

A review on phytochemical constituents and pharmacological potential ofCalotropis procera

RSC Advances, 2021

Calotropis procera is locally known as Aak or Madar in Hindi, milk weed in English and belongs to the family Apocynaceae and subfamily Asclepiadoideae. Although a wasteland plant, it is of sacred use as its flowers are offered for worshipping Lord Shiva, a Hindu God. Tribes all over the world use the plant in treatment of various diseases like snake bite, body pain, asthma, epilepsy, cancer, sexual disorders, skin diseases and many more. This plant contains various phytoconstituents such as flavonoids, terpenoids, cardenolides, steroids oxypregnanes etc. Though literature searches reveal many reviews about ethnomedicinal uses, chemical composition and pharmacological activities, no recent papers are available that provide an overview of the therapeutic potential and toxicity of Calotropis procera. Hence, the insight of this review is to provide a systemic summary of phytochemistry, pharmacology, toxicology and therapeutic potential of Calotropis procera and to highlight the gaps in the knowledge so as to offer inspiration for future research.

PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF CALOTROPIS GIGANTEA

Calotropis gigantea belonging to the Asclepiadaceae family, is a glabrous or hairy, lactiferous shrubs or small trees, commonly known as "the swallow-wort or milkweed". Calotropis gigantea is a well known medicinal herb commonly known as crown flower/ giant milkweed. It has been used for years Unani, Ayurveda and Siddha system of medicine. Herbal medicines can be used to treat a variety of chronic inflammatory illnesses, like rheumatoid arthritis, psoriasis and leprosy. Objective: Calotropis gigantea, is a versatile medicinal herb. It also known as a "Madar", it has a huge history of traditional uses in medical systems like Unani, Ayurveda, and Siddha. It mainly well known for effective treatment for various chronic inflammatory conditions such as psoriasis, rheumatoid arthritis and leprosy. Calotropis gigantea stands out for its therapeutic versatility and wide range of applications. From its root to its flowers, different parts of Calotropis gigantea are known for their medicinal properties. Its potential includes wide spectrum of pharmacological activities, medicinal properties, healing properties making it a promising candidate for the development of novel effective drugs. This has been used in folk medicines for the treatment of bronchitis, asthma, leprosy, eczema and elephantiasis. Although the whole plant is used for skin diseases. Calotropis gigantea are used to treat snake bites, toothache, scorpion stings, fevers, and agues, intestinal diseases, powdered root bark have the ability to cure elephantiasis, dysentery, the stem bark is important for gastrointestinal, lung disease, spleen complaints, ringworm and pneumonia. Conclusion: This review emphasizes on the phytochemistry, uses, pharmacological profile of Calotropis gigantea.

ArticlePHARMACOLOGICAL AND BOTANICAL PROFILE OF CALOTROPIS PROCERA-A MULTI-POTENTIAL PLANT TO HUMANKIND

World Journal of Pharmaceutical and life sciences, 2024

Medicinal plants are a rich source of pharmaceuticals; in fact, the majority of drugs on the market are derived from various types of plants or herb species. Many crude products not only provided the basis for many medicines, but they also had significant therapeutic effects. Calotropis procera Linn is an ayurvedic plant that has long been used to make traditional medicines to treat a wide range of diseases. It is regarded a medicinal plant belonging to the Asclepiadaceae family, which is distributed throughout India and other tropical areas. The collected product from roots, barks, leaves, flowers, and other parts has a variety of therapeutic properties that are extremely beneficial. C.procera possess a wide range of pharmacological activities such as anticancer, antidiabetic, analgesic, anti- inflammatory, anthelmintic, antimicrobial, antidiarroheal, anticonvulsant, hepatoprotective, antioestrogenic, antiulcer, antimalarial, anti-fertility etc. The phytochemical constituents of this plant revealed that it includes cardiac glycosides, triterpenoids, flavonoids, cardenolide, tannis, saponins, resins. Latex of C.procera contain a powerful bacteriolytic enzyme called calactin, which is a cardiotoxin and a robust nontoxic proteolytic enzyme called calotropin. Calotropis procera's macroscopic and microscopic features, as well as its general phytochemical constituents and pharmacological action, are the subject of the current review.

Comprehensive Exploration of the Pharmacological Importance of Calotropis (AKK) Species: A Review

Irish Interdisciplinary Journal of Science & Research (IIJSR) , 2024

Plant have been used for medical purpose from the past and today their use become more. The ethno-pharmacology is as old as man himself. Herbal medicines show a significant therapeutic diversity. Calotropis species includes Calotropis acia bunch, Calotropis gigantea and Calotropis procera are used in several traditional medicines to treat different diseases. The bark and leaves of Calotropis plant have shown anti-diarrheal activity, antimicrobial activity, antifungal activity, anti-inflammatory activity, antioxidant activity, anti-tumor activity, anti-malarial activity, analgesic activity, antifertility activity, pregnancy interceptive activity, anthelmintic activity, hepatoprotective activity, antinociceptive activities, anti- hyperglycemic activity, anti-convulsant, sedative activity and antinociceptive activities. In this review we are going to discuss about Calotropis, its species with different activities which are useful for humans to treat different disease.