Optic Disk Pit Maculopathy Treatment Using a Human Amniotic Membrane Patch: One-Year Results (original) (raw)

American Journal of Ophthalmology, 2022

Abstract

PURPOSE To report the 1-year results of human amniotic membrane patch implantation for optic disc pit maculopathy. DESIGN This is a prospective, consecutive, interventional study. METHODS • Setting: Single institution. • Patient: We included 11 eyes of 11 patients affected by optic disc pit maculopathy associated with sub/intra retinal fluid. • Intervention: A 25-gauge pars plana vitrectomy was performed in all cases, with an implant of a human amniotic membrane patch into the optic disc pit and air was injected as endotamponade.• Main outcomes and measures: The primary study outcome was the subretinal and intraretinal fluid reabsorption. Secondary outcomes were the visual acuity improvement and postoperative complications. RESULTS Mean central retinal thickness gradually diminished from 512 ± 137 µm to 243 ± 19 µm, at the 12-months follow-up. The mean visual acuity improved form 20/80 at baseline to 20/32 at the 12-months follow-up. A complete fluid resorption occurred in 9 eyes on 11 (81.8%) and a partial resorption in 2 eyes (18%). We did not observe any subretinal fluid recurrence during the 12 months follow-up. No intraoperative nor postoperative complications were reported during the follow-ups. The amniotic membrane patch remained detectable inside the pit for the entire follow-up time. CONCLUSION An amniotic membrane plug may be effective to improve optic disc pit maculopathy. All cases had an anatomical improvement and an encouraging visual acuity recovery.

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